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OPENSEQ.org
RSMJ - Ribosomal RNA small subunit methyltransferase J
UniProt: P68567 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12233
Length: 250 (249)
Sequences: 431
Seq/Len: 1.73
RSMJ
Paralog alert: 0.00 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
116_L 152_A 3.2 1.00
57_V 129_G 2.391 1.00
166_Q 212_T 2.37 1.00
97_A 115_M 2.283 1.00
35_L 44_L 2.143 0.99
16_L 20_A 2.063 0.99
41_H 56_F 2.036 0.99
152_A 157_A 1.936 0.98
100_G 126_L 1.854 0.97
118_R 195_G 1.826 0.97
128_D 132_R 1.769 0.96
115_M 147_L 1.769 0.96
82_V 106_L 1.766 0.96
93_V 165_P 1.687 0.95
79_A 109_V 1.667 0.94
206_P 210_L 1.604 0.93
174_F 240_H 1.603 0.93
97_A 149_L 1.597 0.92
175_P 219_R 1.574 0.92
66_H 70_F 1.559 0.91
217_V 226_L 1.554 0.91
76_E 143_L 1.511 0.89
118_R 153_S 1.454 0.87
204_L 217_V 1.449 0.86
73_G 105_V 1.442 0.86
182_L 188_R 1.435 0.86
116_L 157_A 1.425 0.85
114_R 165_P 1.421 0.85
91_D 112_R 1.415 0.85
17_S 21_A 1.403 0.84
174_F 224_P 1.398 0.84
38_T 43_E 1.398 0.84
22_R 127_D 1.383 0.83
232_P 246_A 1.382 0.83
61_G 65_A 1.362 0.81
9_T 12_G 1.355 0.81
12_G 15_A 1.333 0.79
131_A 141_G 1.323 0.79
82_V 167_V 1.31 0.78
103_A 115_M 1.296 0.77
205_E 229_V 1.289 0.76
225_P 234_A 1.287 0.76
16_L 23_W 1.285 0.76
176_H 188_R 1.283 0.76
5_L 8_E 1.281 0.76
33_M 247_G 1.275 0.75
68_R 105_V 1.273 0.75
204_L 208_R 1.262 0.74
237_T 240_H 1.244 0.73
73_G 180_S 1.229 0.71
76_E 109_V 1.215 0.70
155_L 202_G 1.212 0.70
2_K 26_E 1.212 0.70
14_G 29_E 1.208 0.69
76_E 240_H 1.195 0.68
101_R 186_E 1.194 0.68
195_G 199_D 1.193 0.68
116_L 133_G 1.177 0.66
81_A 216_V 1.171 0.66
131_A 135_A 1.167 0.65
180_S 238_K 1.15 0.64
64_M 76_E 1.15 0.64
68_R 72_G 1.148 0.64
112_R 205_E 1.147 0.64
75_G 187_M 1.145 0.63
118_R 199_D 1.144 0.63
74_R 85_K 1.143 0.63
38_T 45_R 1.137 0.63
59_F 147_L 1.133 0.62
220_P 241_R 1.131 0.62
62_G 65_A 1.131 0.62
9_T 40_E 1.131 0.62
42_L 124_A 1.13 0.62
233_N 244_I 1.121 0.61
177_K 183_V 1.12 0.61
154_S 203_L 1.12 0.61
2_K 7_D 1.117 0.60
82_V 111_C 1.117 0.60
121_V 191_Q 1.116 0.60
66_H 105_V 1.112 0.60
217_V 245_Y 1.109 0.60
170_L 203_L 1.107 0.59
187_M 217_V 1.107 0.59
143_L 147_L 1.105 0.59
119_N 174_F 1.102 0.59
174_F 235_V 1.096 0.58
6_I 26_E 1.096 0.58
170_L 219_R 1.095 0.58
23_W 151_H 1.093 0.58
15_A 40_E 1.092 0.58
88_Y 249_P 1.087 0.57
109_V 177_K 1.082 0.57
78_V 106_L 1.08 0.57
97_A 126_L 1.078 0.56
8_E 38_T 1.076 0.56
157_A 161_I 1.075 0.56
37_L 131_A 1.075 0.56
170_L 226_L 1.072 0.56
73_G 76_E 1.07 0.56
62_G 133_G 1.07 0.56
19_L 37_L 1.063 0.55
66_H 75_G 1.059 0.54
152_A 177_K 1.056 0.54
235_V 246_A 1.054 0.54
208_R 247_G 1.052 0.54
219_R 245_Y 1.05 0.53
68_R 217_V 1.047 0.53
235_V 239_G 1.044 0.53
211_A 215_V 1.044 0.53
77_A 240_H 1.042 0.53
46_K 49_E 1.035 0.52
74_R 78_V 1.035 0.52
21_A 40_E 1.034 0.52
187_M 190_F 1.03 0.51
175_P 220_P 1.027 0.51
114_R 148_Q 1.025 0.51
174_F 193_L 1.025 0.51
153_S 158_L 1.023 0.51
168_V 206_P 1.023 0.51
221_D 237_T 1.022 0.50
7_D 13_D 1.021 0.50
57_V 244_I 1.012 0.49
7_D 56_F 1.007 0.49
177_K 191_Q 1.007 0.49
109_V 167_V 1.007 0.49
82_V 169_Y 1.004 0.48
4_C 15_A 1.001 0.48
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2oyrA111000.465Contact Map0.452
2r6zA20.961000.501Contact Map0.544
2dulA10.79298.40.876Contact Map0.58
3axsA10.76498.30.879Contact Map0.504
3ll7A10.8898.10.885Contact Map0.354
3c0kA20.896980.89Contact Map0.459
2as0A20.91297.90.89Contact Map0.417
2ozvA20.74497.70.895Contact Map0.537
1dusA10.74897.70.896Contact Map0.555
2b78A10.89297.60.897Contact Map0.525
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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