| UniProt: | P67080 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12979 | ||
| Length: | 234 (231) | ||
| Sequences: | 2117 | ||
| Seq/Len: | 9.16 |
| YGGS
Paralog alert: 0.03 [within 20: 0.00] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 53_Q | 78_E | 3.285 | 1.00 | |
| 14_K | 209_E | 3.262 | 1.00 | |
| 124_N | 159_R | 2.889 | 1.00 | |
| 19_A | 29_I | 2.723 | 1.00 | |
| 177_F | 214_A | 2.714 | 1.00 | |
| 113_N | 157_R | 2.444 | 1.00 | |
| 184_A | 188_A | 2.435 | 1.00 | |
| 84_P | 138_S | 2.399 | 1.00 | |
| 38_K | 42_A | 2.399 | 1.00 | |
| 140_I | 148_L | 2.395 | 1.00 | |
| 87_S | 107_R | 2.327 | 1.00 | |
| 62_G | 97_F | 2.163 | 1.00 | |
| 163_L | 200_L | 2.109 | 1.00 | |
| 44_A | 48_D | 2.094 | 1.00 | |
| 199_T | 217_T | 2.086 | 1.00 | |
| 47_I | 52_R | 1.992 | 1.00 | |
| 181_R | 214_A | 1.863 | 1.00 | |
| 35_S | 54_F | 1.841 | 1.00 | |
| 34_V | 82_I | 1.824 | 1.00 | |
| 15_I | 212_I | 1.806 | 1.00 | |
| 106_L | 110_T | 1.794 | 1.00 | |
| 15_I | 31_L | 1.793 | 1.00 | |
| 21_R | 213_A | 1.785 | 1.00 | |
| 32_L | 218_M | 1.777 | 1.00 | |
| 106_L | 151_A | 1.755 | 1.00 | |
| 124_N | 161_R | 1.753 | 1.00 | |
| 14_K | 208_M | 1.751 | 1.00 | |
| 103_I | 112_L | 1.736 | 1.00 | |
| 110_T | 151_A | 1.733 | 1.00 | |
| 30_T | 199_T | 1.716 | 1.00 | |
| 221_I | 224_A | 1.707 | 1.00 | |
| 177_F | 213_A | 1.687 | 1.00 | |
| 52_R | 76_G | 1.684 | 1.00 | |
| 111_R | 114_D | 1.663 | 1.00 | |
| 142_L | 186_A | 1.627 | 1.00 | |
| 117_P | 157_R | 1.621 | 1.00 | |
| 99_W | 126_L | 1.59 | 1.00 | |
| 47_I | 77_L | 1.578 | 1.00 | |
| 113_N | 156_P | 1.564 | 1.00 | |
| 111_R | 115_Q | 1.553 | 1.00 | |
| 205_S | 224_A | 1.55 | 1.00 | |
| 44_A | 71_E | 1.544 | 1.00 | |
| 39_P | 42_A | 1.543 | 1.00 | |
| 103_I | 125_V | 1.517 | 1.00 | |
| 187_F | 191_K | 1.508 | 1.00 | |
| 161_R | 198_D | 1.503 | 1.00 | |
| 127_I | 148_L | 1.479 | 1.00 | |
| 101_H | 218_M | 1.46 | 1.00 | |
| 19_A | 27_E | 1.433 | 0.99 | |
| 59_V | 85_L | 1.419 | 0.99 | |
| 94_A | 123_L | 1.409 | 0.99 | |
| 113_N | 155_L | 1.396 | 0.99 | |
| 144_E | 147_E | 1.392 | 0.99 | |
| 47_I | 54_F | 1.383 | 0.99 | |
| 19_A | 26_P | 1.343 | 0.99 | |
| 12_R | 26_P | 1.343 | 0.99 | |
| 59_V | 81_F | 1.328 | 0.99 | |
| 147_E | 150_A | 1.318 | 0.99 | |
| 25_S | 28_E | 1.314 | 0.99 | |
| 13_D | 17_A | 1.313 | 0.99 | |
| 33_A | 51_Q | 1.312 | 0.99 | |
| 172_E | 175_R | 1.291 | 0.99 | |
| 149_A | 160_L | 1.287 | 0.99 | |
| 37_T | 57_N | 1.282 | 0.99 | |
| 115_Q | 118_A | 1.281 | 0.99 | |
| 85_L | 93_V | 1.266 | 0.98 | |
| 129_I | 145_L | 1.265 | 0.98 | |
| 4_I | 46_A | 1.26 | 0.98 | |
| 131_I | 183_M | 1.257 | 0.98 | |
| 60_Q | 88_N | 1.249 | 0.98 | |
| 81_F | 93_V | 1.234 | 0.98 | |
| 184_A | 214_A | 1.228 | 0.98 | |
| 87_S | 105_R | 1.226 | 0.98 | |
| 126_L | 199_T | 1.217 | 0.98 | |
| 66_I | 97_F | 1.209 | 0.98 | |
| 8_L | 46_A | 1.205 | 0.98 | |
| 42_A | 45_E | 1.199 | 0.98 | |
| 90_S | 112_L | 1.185 | 0.97 | |
| 5_A | 9_A | 1.181 | 0.97 | |
| 90_S | 108_I | 1.18 | 0.97 | |
| 19_A | 28_E | 1.174 | 0.97 | |
| 62_G | 66_I | 1.172 | 0.97 | |
| 109_A | 155_L | 1.159 | 0.97 | |
| 105_R | 108_I | 1.159 | 0.97 | |
| 87_S | 108_I | 1.15 | 0.97 | |
| 30_T | 53_Q | 1.147 | 0.97 | |
| 18_A | 22_C | 1.144 | 0.96 | |
| 128_Q | 166_I | 1.139 | 0.96 | |
| 63_V | 96_H | 1.139 | 0.96 | |
| 46_A | 49_A | 1.133 | 0.96 | |
| 47_I | 76_G | 1.132 | 0.96 | |
| 182_Q | 185_V | 1.109 | 0.96 | |
| 165_A | 183_M | 1.109 | 0.96 | |
| 32_L | 101_H | 1.094 | 0.95 | |
| 93_V | 97_F | 1.085 | 0.95 | |
| 11_V | 221_I | 1.076 | 0.94 | |
| 184_A | 187_F | 1.075 | 0.94 | |
| 150_A | 193_R | 1.073 | 0.94 | |
| 16_S | 20_T | 1.067 | 0.94 | |
| 104_D | 108_I | 1.066 | 0.94 | |
| 163_L | 186_A | 1.064 | 0.94 | |
| 180_A | 202_L | 1.064 | 0.94 | |
| 126_L | 218_M | 1.064 | 0.94 | |
| 85_L | 108_I | 1.063 | 0.94 | |
| 64_D | 68_H | 1.061 | 0.94 | |
| 116_R | 123_L | 1.057 | 0.94 | |
| 8_L | 51_Q | 1.046 | 0.93 | |
| 113_N | 117_P | 1.046 | 0.93 | |
| 109_A | 158_L | 1.043 | 0.93 | |
| 133_D | 143_A | 1.037 | 0.93 | |
| 146_D | 189_G | 1.026 | 0.92 | |
| 168_A | 179_V | 1.023 | 0.92 | |
| 140_I | 145_L | 1.022 | 0.92 | |
| 151_A | 154_E | 1.017 | 0.92 | |
| 90_S | 111_R | 1.017 | 0.92 | |
| 223_T | 227_G | 1.017 | 0.92 | |
| 58_Y | 102_T | 1.017 | 0.92 | |
| 109_A | 152_V | 1.012 | 0.92 | |
| 127_I | 140_I | 1.008 | 0.92 | |
| 32_L | 53_Q | 1.005 | 0.91 | |
| 4_I | 49_A | 1.003 | 0.91 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3sy1A | 1 | 1 | 100 | 0.506 | Contact Map | 0.725 |
| 1ct5A | 1 | 0.9744 | 100 | 0.508 | Contact Map | 0.786 |
| 3cpgA | 1 | 1 | 100 | 0.509 | Contact Map | 0.831 |
| 3r79A | 2 | 0.9615 | 100 | 0.526 | Contact Map | 0.801 |
| 4dzaA | 1 | 0.953 | 100 | 0.617 | Contact Map | 0.535 |
| 3e5pA | 3 | 0.9402 | 100 | 0.622 | Contact Map | 0.582 |
| 4dyjA | 2 | 0.953 | 100 | 0.623 | Contact Map | 0.55 |
| 4a3qA | 2 | 0.9316 | 100 | 0.627 | Contact Map | 0.604 |
| 3kw3A | 2 | 0.9402 | 100 | 0.628 | Contact Map | 0.576 |
| 1bd0A | 2 | 0.9359 | 100 | 0.63 | Contact Map | 0.626 |
Sequence Conservation (Image Generated using WebLogo v3)