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OPENSEQ.org
YPFJ - Uncharacterized protein YpfJ
UniProt: P64429 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG14197
Length: 287 (282)
Sequences: 586
Seq/Len: 2.08
YPFJ
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
179_I 209_F 4.28 1.00
119_T 124_G 3.67 1.00
120_G 135_A 3.357 1.00
158_D 230_E 3.201 1.00
7_R 92_D 2.882 1.00
141_I 146_Y 2.795 1.00
208_C 280_C 2.69 1.00
8_E 81_K 2.624 1.00
262_Q 266_S 2.617 1.00
148_D 152_K 2.401 1.00
7_R 88_A 2.36 1.00
106_Q 137_G 2.307 1.00
276_D 279_Q 2.277 1.00
184_R 187_Q 2.229 1.00
117_T 124_G 2.221 1.00
155_A 234_A 2.21 1.00
234_A 238_I 2.151 1.00
3_W 85_V 2.131 0.99
125_Q 128_M 2.068 0.99
180_E 202_M 2.061 0.99
113_Y 117_T 2.033 0.99
281_N 284_G 1.981 0.99
95_G 107_Q 1.927 0.99
256_F 260_T 1.915 0.99
5_G 85_V 1.901 0.99
183_V 198_L 1.875 0.98
117_T 128_M 1.855 0.98
228_L 272_F 1.836 0.98
113_Y 124_G 1.777 0.97
124_G 128_M 1.714 0.97
6_R 85_V 1.713 0.97
13_E 138_T 1.71 0.97
267_W 283_F 1.695 0.96
90_T 169_V 1.66 0.96
148_D 242_R 1.644 0.95
137_G 175_K 1.605 0.95
88_A 91_E 1.6 0.95
212_V 277_P 1.596 0.94
175_K 180_E 1.559 0.93
91_E 108_P 1.556 0.93
106_Q 176_L 1.542 0.93
229_E 265_Y 1.541 0.93
252_V 255_S 1.539 0.93
176_L 179_I 1.537 0.93
242_R 246_Q 1.517 0.92
238_I 243_L 1.514 0.92
15_R 111_V 1.503 0.92
114_R 147_D 1.476 0.91
53_D 56_G 1.461 0.90
117_T 125_Q 1.456 0.90
4_Q 85_V 1.425 0.89
270_R 279_Q 1.42 0.88
153_L 243_L 1.412 0.88
268_F 272_F 1.409 0.88
244_Q 249_G 1.403 0.88
124_G 146_Y 1.395 0.87
184_R 202_M 1.389 0.87
4_Q 78_E 1.371 0.86
88_A 92_D 1.369 0.86
267_W 282_T 1.343 0.84
237_A 242_R 1.332 0.84
109_K 139_V 1.33 0.84
232_L 236_Q 1.31 0.82
105_Y 139_V 1.309 0.82
3_W 6_R 1.303 0.82
83_T 110_L 1.299 0.82
226_G 229_E 1.299 0.82
214_G 228_L 1.287 0.81
49_Y 52_V 1.283 0.80
174_Q 205_Q 1.267 0.79
269_K 273_D 1.249 0.78
53_D 59_T 1.235 0.77
83_T 165_I 1.233 0.77
260_T 263_Q 1.213 0.75
110_L 169_V 1.209 0.75
5_G 8_E 1.205 0.74
248_Q 252_V 1.197 0.74
175_K 181_P 1.196 0.74
194_E 197_R 1.189 0.73
269_K 272_F 1.181 0.72
143_L 146_Y 1.175 0.72
80_A 84_S 1.174 0.72
265_Y 269_K 1.173 0.72
246_Q 249_G 1.171 0.71
9_S 87_L 1.169 0.71
180_E 184_R 1.161 0.70
205_Q 209_F 1.157 0.70
93_T 97_Q 1.156 0.70
243_L 247_S 1.151 0.69
36_G 39_I 1.149 0.69
149_M 152_K 1.141 0.68
231_A 268_F 1.14 0.68
85_V 89_T 1.136 0.68
161_Q 238_I 1.117 0.66
161_Q 208_C 1.111 0.65
173_V 177_L 1.11 0.65
161_Q 280_C 1.106 0.65
113_Y 128_M 1.102 0.65
274_S 279_Q 1.1 0.64
183_V 202_M 1.099 0.64
225_T 273_D 1.09 0.63
119_T 146_Y 1.083 0.63
47_A 52_V 1.081 0.62
147_D 151_D 1.08 0.62
8_E 85_V 1.068 0.61
9_S 91_E 1.066 0.61
214_G 272_F 1.046 0.59
217_M 222_V 1.044 0.58
266_S 270_R 1.042 0.58
170_G 210_A 1.04 0.58
36_G 40_L 1.034 0.57
201_R 266_S 1.026 0.56
149_M 155_A 1.021 0.56
224_E 229_E 1.021 0.56
245_Q 250_R 1.02 0.56
6_R 89_T 1.019 0.56
116_M 123_A 1.015 0.55
91_E 110_L 1.007 0.54
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3c37A20.714390.40.959Contact Map0.447
3cqbA20.372889.50.96Contact Map0.373
4il3A20.797987.70.961Contact Map0.304
1c7kA10.442561.50.969Contact Map0.209
3ayuA10.533157.30.97Contact Map0.183
4h1qA20.515745.70.972Contact Map0.204
1y93A10.501741.40.973Contact Map0.114
2jsdA10.512240.30.973Contact Map0.126
1i76A10.512236.40.974Contact Map0.169
2ejqA20.386829.80.975Contact Map0.318
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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