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OPENSEQ.org

LGT - Prolipoprotein diacylglyceryl transferase
UniProt: P60955 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12128
Length: 291 (268)
Sequences: 1937
Seq/Len: 7.23

LGT
Paralog alert: 0.05 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
91_Y 97_D 3.382 1.00
196_H 201_Y 3.155 1.00
157_D 163_A 2.915 1.00
27_G 31_L 2.797 1.00
91_Y 94_R 2.794 1.00
241_I 245_F 2.697 1.00
84_Q 88_D 2.389 1.00
17_S 22_A 2.325 1.00
144_L 203_L 2.309 1.00
82_F 86_M 2.291 1.00
124_F 128_S 2.274 1.00
88_D 91_Y 2.257 1.00
115_I 119_R 2.211 1.00
16_F 23_L 2.13 1.00
103_H 263_G 2.116 1.00
233_I 274_G 2.072 1.00
94_R 97_D 2.036 1.00
160_F 163_A 1.966 1.00
205_L 238_F 1.937 1.00
67_G 112_V 1.937 1.00
236_G 271_I 1.887 1.00
84_Q 91_Y 1.85 1.00
15_I 23_L 1.845 1.00
229_G 274_G 1.843 1.00
56_E 120_T 1.827 1.00
15_I 28_L 1.811 1.00
276_I 280_W 1.796 1.00
71_G 108_G 1.793 1.00
240_I 264_Q 1.775 1.00
226_A 282_Y 1.749 1.00
53_T 56_E 1.726 1.00
114_I 118_R 1.72 1.00
117_A 127_V 1.72 1.00
45_A 57_V 1.71 1.00
240_I 244_F 1.668 1.00
233_I 271_I 1.656 1.00
46_N 54_K 1.656 1.00
209_V 234_G 1.629 1.00
156_V 193_L 1.615 1.00
67_G 108_G 1.607 1.00
86_M 89_P 1.603 1.00
17_S 20_P 1.598 1.00
116_F 120_T 1.581 1.00
90_L 93_F 1.556 1.00
229_G 277_M 1.533 0.99
146_N 151_E 1.531 0.99
210_L 234_G 1.519 0.99
89_P 93_F 1.518 0.99
29_M 145_G 1.514 0.99
205_L 242_V 1.504 0.99
139_L 231_F 1.495 0.99
226_A 278_M 1.469 0.99
44_R 218_I 1.465 0.99
212_I 216_L 1.457 0.99
34_F 68_V 1.454 0.99
230_L 278_M 1.443 0.99
78_L 82_F 1.424 0.99
233_I 275_V 1.423 0.99
34_F 65_F 1.422 0.99
68_V 109_V 1.394 0.99
95_V 98_G 1.392 0.99
37_A 64_G 1.379 0.99
108_G 112_V 1.372 0.99
77_V 92_L 1.36 0.99
125_F 225_G 1.354 0.98
159_N 163_A 1.346 0.98
170_R 192_V 1.339 0.98
128_S 228_S 1.335 0.98
60_L 127_V 1.314 0.98
41_A 134_L 1.314 0.98
147_F 200_L 1.306 0.98
203_L 208_V 1.303 0.98
113_M 128_S 1.291 0.98
238_F 242_V 1.283 0.98
66_L 70_L 1.28 0.98
13_P 24_H 1.27 0.97
268_I 272_V 1.241 0.97
85_F 92_L 1.236 0.97
74_I 92_L 1.235 0.97
166_F 199_Q 1.234 0.97
146_N 149_N 1.229 0.97
88_D 94_R 1.223 0.97
42_T 58_E 1.213 0.96
44_R 47_R 1.212 0.96
15_I 25_W 1.209 0.96
111_V 115_I 1.207 0.96
102_F 139_L 1.204 0.96
114_I 124_F 1.204 0.96
232_L 274_G 1.198 0.96
85_F 91_Y 1.192 0.96
15_I 24_H 1.19 0.96
210_L 214_L 1.172 0.95
147_F 164_M 1.17 0.95
217_Y 230_L 1.169 0.95
237_A 271_I 1.167 0.95
140_G 203_L 1.165 0.95
44_R 133_P 1.164 0.95
244_F 264_Q 1.162 0.95
39_W 43_R 1.159 0.95
162_F 196_H 1.147 0.95
141_A 203_L 1.14 0.94
163_A 194_P 1.139 0.94
81_N 84_Q 1.136 0.94
101_S 152_L 1.125 0.94
55_N 58_E 1.122 0.94
230_L 234_G 1.121 0.94
153_W 195_R 1.119 0.94
169_S 192_V 1.117 0.93
126_Q 224_M 1.109 0.93
195_R 247_Q 1.108 0.93
26_Y 146_N 1.104 0.93
263_G 266_L 1.101 0.93
43_R 46_N 1.101 0.93
38_M 61_L 1.099 0.93
233_I 278_M 1.098 0.93
260_I 268_I 1.09 0.92
275_V 279_V 1.089 0.92
106_L 135_I 1.086 0.92
40_L 215_N 1.08 0.92
278_M 282_Y 1.076 0.92
155_R 247_Q 1.065 0.91
70_L 74_I 1.051 0.90
156_V 194_P 1.05 0.90
146_N 152_L 1.042 0.90
143_R 239_R 1.04 0.90
200_L 204_L 1.037 0.90
229_G 278_M 1.033 0.89
137_F 140_G 1.026 0.89
76_Y 252_F 1.022 0.89
165_L 194_P 1.021 0.89
43_R 47_R 1.02 0.89
198_S 242_V 1.004 0.88
81_N 85_F 1 0.87
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2kluA10.147820.30.964Contact Map0.62
2ls4A10.08256.70.971Contact Map0.11
2zxeA10.20275.70.972Contact Map0.067
3ixzA10.20275.50.972Contact Map0.002
2rddB10.1130.975Contact Map0.107
2l2tA20.12712.80.976Contact Map0.271
2ks1B10.14092.60.976Contact Map0.476
2l9uA20.13752.50.976Contact Map0.773
3aqpA20.23371.80.978Contact Map0.196
2jwaA20.15121.60.979Contact Map0.677

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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