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OPENSEQ.org
YGAP - Inner membrane protein YgaP
UniProt: P55734 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13288
Length: 174 (173)
Sequences: 245
Seq/Len: 1.42
YGAP
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
131_L 139_F 2.401 1.00
26_D 44_S 2.298 0.99
30_Y 34_H 2.057 0.98
61_I 89_L 1.978 0.98
114_M 118_Q 1.855 0.96
33_E 97_K 1.832 0.96
7_S 10_D 1.83 0.96
156_S 166_D 1.799 0.95
11_A 61_I 1.789 0.95
132_G 140_F 1.7 0.93
36_P 75_D 1.676 0.92
129_V 140_F 1.648 0.91
124_L 142_L 1.603 0.90
70_T 88_L 1.6 0.90
119_I 154_G 1.567 0.88
98_K 156_S 1.539 0.87
110_P 114_M 1.536 0.87
35_I 61_I 1.527 0.86
146_V 164_L 1.515 0.86
132_G 141_L 1.51 0.86
121_A 146_V 1.51 0.86
21_L 63_H 1.49 0.85
151_L 155_I 1.48 0.84
128_G 143_S 1.454 0.83
41_A 138_G 1.433 0.81
24_I 73_N 1.388 0.78
91_D 95_G 1.378 0.78
2_A 6_I 1.366 0.77
65_Q 112_P 1.354 0.76
12_Q 16_A 1.351 0.76
11_A 19_A 1.31 0.72
152_F 156_S 1.297 0.71
76_K 86_I 1.273 0.69
8_P 102_P 1.266 0.69
152_F 155_I 1.263 0.68
98_K 103_V 1.255 0.68
20_K 41_A 1.254 0.68
38_A 93_I 1.253 0.68
128_G 142_L 1.247 0.67
124_L 146_V 1.241 0.66
63_H 118_Q 1.233 0.66
8_P 101_L 1.232 0.66
163_R 167_K 1.218 0.64
72_N 113_L 1.216 0.64
131_L 136_N 1.208 0.63
35_I 63_H 1.205 0.63
70_T 101_L 1.195 0.62
35_I 89_L 1.182 0.61
14_L 87_F 1.176 0.60
111_L 119_I 1.167 0.59
129_V 133_Y 1.165 0.59
35_I 93_I 1.136 0.56
24_I 70_T 1.136 0.56
20_K 58_E 1.133 0.56
97_K 103_V 1.132 0.56
38_A 61_I 1.12 0.55
129_V 144_G 1.119 0.55
135_V 139_F 1.114 0.54
124_L 128_G 1.113 0.54
133_Y 140_F 1.111 0.54
30_Y 40_L 1.107 0.53
113_L 163_R 1.106 0.53
38_A 96_W 1.098 0.53
114_M 146_V 1.096 0.52
8_P 13_E 1.092 0.52
48_Q 127_I 1.088 0.52
118_Q 157_G 1.084 0.51
41_A 46_L 1.073 0.50
65_Q 94_D 1.072 0.50
8_P 130_V 1.07 0.50
80_I 130_V 1.068 0.49
113_L 162_A 1.064 0.49
143_S 167_K 1.055 0.48
11_A 16_A 1.047 0.47
130_V 134_T 1.039 0.47
35_I 101_L 1.038 0.46
14_L 59_Q 1.032 0.46
27_A 105_V 1.029 0.45
160_G 170_W 1.025 0.45
161_M 164_L 1.02 0.45
8_P 39_D 1.02 0.45
10_D 13_E 1.02 0.45
8_P 99_A 1.019 0.44
156_S 160_G 1.011 0.44
26_D 118_Q 1.011 0.44
115_R 122_G 1.009 0.43
6_I 51_L 1.006 0.43
95_G 99_A 1.001 0.43
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1yt8A10.712699.90.634Contact Map0.494
3nhvA50.729999.90.635Contact Map0.455
1tq1A10.59299.90.648Contact Map0.199
1qxnA20.643799.90.648Contact Map0.417
3emeA10.580599.90.649Contact Map0.434
3fojA10.563299.90.651Contact Map0.462
3tp9A20.59299.90.654Contact Map0.502
1gmxA10.609299.90.654Contact Map0.435
3gk5A10.620799.90.655Contact Map0.518
3ntdA20.551799.90.656Contact Map0.402
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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