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OPENSEQ.org

YFHL - Uncharacterized ferredoxin-like protein YfhL
UniProt: P52102 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13215
Length: 86 (82)
Sequences: 892
Seq/Len: 10.88

YFHL
Paralog alert: 0.29 [within 20: 0.01] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
8_K 56_I 2.643 1.00
37_K 80_M 2.363 1.00
25_S 34_N 2.286 1.00
75_D 79_L 2.227 1.00
47_T 52_K 2.204 1.00
66_H 74_W 2.036 1.00
61_V 67_V 1.928 1.00
5_I 24_I 1.9 1.00
68_E 71_E 1.798 1.00
72_Q 75_D 1.758 1.00
13_D 31_Y 1.731 1.00
75_D 78_V 1.726 1.00
18_E 53_V 1.671 1.00
25_S 32_E 1.67 1.00
74_W 78_V 1.585 1.00
23_A 37_K 1.473 1.00
3_L 51_Q 1.451 1.00
2_A 74_W 1.447 1.00
11_N 29_H 1.385 0.99
6_T 61_V 1.371 0.99
30_I 76_K 1.357 0.99
34_N 37_K 1.315 0.99
4_L 64_P 1.255 0.99
2_A 56_I 1.244 0.98
71_E 74_W 1.218 0.98
42_V 70_E 1.197 0.98
69_T 72_Q 1.185 0.98
62_K 67_V 1.171 0.98
63_D 66_H 1.127 0.97
12_C 24_I 1.103 0.96
21_N 39_T 1.096 0.96
5_I 13_D 1.087 0.96
64_P 67_V 1.073 0.95
24_I 81_H 1.07 0.95
30_I 80_M 1.051 0.94
7_K 59_T 1.028 0.94
18_E 39_T 1.01 0.93
23_A 62_K 1.009 0.93
60_I 77_F 1.001 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3eunA10.953599.30.58Contact Map0.533
2fgoA10.953599.30.586Contact Map0.543
2zvsA30.988499.30.591Contact Map0.551
1rgvA10.930299.30.592Contact Map0.516
1bc6A10.872199.20.601Contact Map0.431
7fd1A10.90799.20.601Contact Map0.644
2v2kA20.90799.20.606Contact Map0.532
1h98A10.883799.20.61Contact Map0.636
2fdnA10.639598.90.647Contact Map0.664
1hfeL20.918698.80.659Contact Map0.34

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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