| UniProt: | P52061 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12982 | ||
| Length: | 197 (196) | ||
| Sequences: | 2231 | ||
| Seq/Len: | 11.38 |
| RDGB
Paralog alert: 0.05 [within 20: 0.00] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 43_G | 48_E | 3.88 | 1.00 | |
| 140_W | 169_A | 3.435 | 1.00 | |
| 149_A | 171_E | 3.339 | 1.00 | |
| 99_L | 159_I | 3.185 | 1.00 | |
| 73_A | 117_R | 2.866 | 1.00 | |
| 80_A | 105_T | 2.684 | 1.00 | |
| 173_T | 176_E | 2.542 | 1.00 | |
| 42_T | 52_L | 2.539 | 1.00 | |
| 167_K | 176_E | 2.531 | 1.00 | |
| 117_R | 139_S | 2.506 | 1.00 | |
| 145_T | 168_T | 2.5 | 1.00 | |
| 117_R | 141_P | 2.444 | 1.00 | |
| 3_K | 27_D | 2.42 | 1.00 | |
| 74_V | 102_L | 2.382 | 1.00 | |
| 75_D | 117_R | 2.377 | 1.00 | |
| 111_D | 146_R | 2.37 | 1.00 | |
| 12_G | 15_R | 2.318 | 1.00 | |
| 75_D | 115_Q | 2.209 | 1.00 | |
| 104_E | 107_K | 2.068 | 1.00 | |
| 47_I | 137_H | 2.015 | 1.00 | |
| 136_C | 193_A | 2.004 | 1.00 | |
| 73_A | 119_H | 1.975 | 1.00 | |
| 101_K | 105_T | 1.969 | 1.00 | |
| 50_A | 123_V | 1.966 | 1.00 | |
| 88_Y | 105_T | 1.956 | 1.00 | |
| 75_D | 113_Q | 1.932 | 1.00 | |
| 94_T | 97_K | 1.854 | 1.00 | |
| 6_L | 17_L | 1.839 | 1.00 | |
| 145_T | 161_F | 1.756 | 1.00 | |
| 100_Q | 148_P | 1.744 | 1.00 | |
| 3_K | 29_V | 1.738 | 1.00 | |
| 51_I | 55_R | 1.701 | 1.00 | |
| 72_L | 144_I | 1.68 | 1.00 | |
| 119_H | 137_H | 1.652 | 1.00 | |
| 8_T | 14_V | 1.621 | 1.00 | |
| 96_Q | 100_Q | 1.613 | 1.00 | |
| 19_S | 178_S | 1.599 | 1.00 | |
| 5_V | 57_A | 1.584 | 1.00 | |
| 176_E | 179_A | 1.543 | 1.00 | |
| 89_S | 97_K | 1.467 | 1.00 | |
| 14_V | 30_A | 1.457 | 1.00 | |
| 185_Q | 188_K | 1.455 | 1.00 | |
| 145_T | 149_A | 1.452 | 1.00 | |
| 184_G | 188_K | 1.452 | 1.00 | |
| 99_L | 148_P | 1.435 | 1.00 | |
| 44_L | 48_E | 1.429 | 1.00 | |
| 80_A | 88_Y | 1.421 | 1.00 | |
| 55_R | 59_K | 1.398 | 0.99 | |
| 93_A | 97_K | 1.394 | 0.99 | |
| 39_A | 56_H | 1.371 | 0.99 | |
| 124_Y | 190_L | 1.347 | 0.99 | |
| 54_A | 123_V | 1.34 | 0.99 | |
| 123_V | 135_V | 1.336 | 0.99 | |
| 66_I | 122_L | 1.325 | 0.99 | |
| 55_R | 133_P | 1.322 | 0.99 | |
| 46_F | 70_S | 1.313 | 0.99 | |
| 96_Q | 148_P | 1.306 | 0.99 | |
| 3_K | 63_L | 1.285 | 0.99 | |
| 64_P | 124_Y | 1.274 | 0.99 | |
| 58_A | 127_H | 1.274 | 0.99 | |
| 11_V | 15_R | 1.27 | 0.99 | |
| 161_F | 166_G | 1.268 | 0.99 | |
| 39_A | 52_L | 1.256 | 0.99 | |
| 110_P | 113_Q | 1.239 | 0.98 | |
| 161_F | 164_S | 1.236 | 0.98 | |
| 143_V | 163_P | 1.223 | 0.98 | |
| 51_I | 133_P | 1.219 | 0.98 | |
| 57_A | 65_A | 1.215 | 0.98 | |
| 46_F | 73_A | 1.215 | 0.98 | |
| 17_L | 122_L | 1.203 | 0.98 | |
| 151_T | 171_E | 1.195 | 0.98 | |
| 103_L | 159_I | 1.191 | 0.98 | |
| 9_G | 32_T | 1.18 | 0.98 | |
| 122_L | 187_L | 1.179 | 0.98 | |
| 61_T | 65_A | 1.176 | 0.98 | |
| 89_S | 98_N | 1.156 | 0.97 | |
| 121_V | 136_C | 1.152 | 0.97 | |
| 72_L | 118_F | 1.146 | 0.97 | |
| 36_V | 61_T | 1.14 | 0.97 | |
| 169_A | 172_L | 1.133 | 0.97 | |
| 102_L | 159_I | 1.132 | 0.97 | |
| 45_T | 83_I | 1.122 | 0.97 | |
| 172_L | 176_E | 1.122 | 0.97 | |
| 165_E | 176_E | 1.12 | 0.96 | |
| 143_V | 161_F | 1.108 | 0.96 | |
| 56_H | 60_V | 1.098 | 0.96 | |
| 98_N | 101_K | 1.092 | 0.96 | |
| 58_A | 125_L | 1.09 | 0.96 | |
| 47_I | 123_V | 1.089 | 0.96 | |
| 70_S | 120_C | 1.067 | 0.95 | |
| 108_D | 146_R | 1.056 | 0.95 | |
| 51_I | 125_L | 1.046 | 0.94 | |
| 52_L | 56_H | 1.035 | 0.94 | |
| 141_P | 163_P | 1.032 | 0.94 | |
| 164_S | 185_Q | 1.03 | 0.94 | |
| 29_V | 34_L | 1.027 | 0.94 | |
| 51_I | 123_V | 1.027 | 0.94 | |
| 99_L | 158_P | 1.025 | 0.93 | |
| 119_H | 139_S | 1.016 | 0.93 | |
| 100_Q | 104_E | 1.01 | 0.93 | |
| 89_S | 101_K | 1.01 | 0.93 | |
| 5_V | 65_A | 1.007 | 0.93 | |
| 152_G | 173_T | 1.006 | 0.93 | |
| 103_L | 114_R | 1.004 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1k7kA | 1 | 1 | 100 | -0.011 | Contact Map | 0.736 |
| 3tquA | 4 | 1 | 100 | 0.032 | Contact Map | 0.774 |
| 1vp2A | 2 | 0.9492 | 100 | 0.033 | Contact Map | 0.81 |
| 1v7rA | 1 | 0.9289 | 100 | 0.055 | Contact Map | 0.726 |
| 1b78A | 2 | 0.9289 | 100 | 0.062 | Contact Map | 0.773 |
| 4bnqA | 2 | 0.9695 | 100 | 0.068 | Contact Map | 0.843 |
| 2carA | 2 | 0.9391 | 100 | 0.068 | Contact Map | 0.749 |
| 2amhA | 1 | 0.7817 | 94.7 | 0.903 | Contact Map | 0.435 |
| 4jhcA | 2 | 0.7716 | 93.8 | 0.907 | Contact Map | 0.605 |
| 1ex2A | 2 | 0.7614 | 93.3 | 0.909 | Contact Map | 0.541 |
Sequence Conservation (Image Generated using WebLogo v3)