| UniProt: | P46846 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12934 | ||
| Length: | 227 (225) | ||
| Sequences: | 1766 | ||
| Seq/Len: | 7.85 |
| GNTX
Paralog alert: 0.00 [within 20: 0.00] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 119_V | 206_I | 3.866 | 1.00 | |
| 203_V | 220_V | 3.653 | 1.00 | |
| 163_Q | 174_N | 3.476 | 1.00 | |
| 197_V | 222_C | 3.089 | 1.00 | |
| 154_V | 206_I | 3.077 | 1.00 | |
| 167_S | 170_L | 2.892 | 1.00 | |
| 51_C | 54_C | 2.708 | 1.00 | |
| 37_C | 40_C | 2.683 | 1.00 | |
| 62_Q | 211_L | 2.64 | 1.00 | |
| 181_L | 209_L | 2.614 | 1.00 | |
| 142_S | 149_W | 2.532 | 1.00 | |
| 121_L | 133_Q | 2.523 | 1.00 | |
| 23_C | 26_C | 2.443 | 1.00 | |
| 189_H | 217_A | 2.412 | 1.00 | |
| 68_A | 74_L | 2.407 | 1.00 | |
| 40_C | 51_C | 2.347 | 1.00 | |
| 116_I | 191_V | 2.315 | 1.00 | |
| 94_S | 98_L | 2.307 | 1.00 | |
| 168_A | 172_K | 2.267 | 1.00 | |
| 40_C | 54_C | 2.215 | 1.00 | |
| 8_C | 11_C | 2.186 | 1.00 | |
| 66_T | 222_C | 2.162 | 1.00 | |
| 192_I | 206_I | 2.158 | 1.00 | |
| 205_E | 208_Q | 2.071 | 1.00 | |
| 83_F | 164_H | 1.987 | 1.00 | |
| 60_P | 204_A | 1.927 | 1.00 | |
| 205_E | 209_L | 1.891 | 1.00 | |
| 166_L | 174_N | 1.889 | 1.00 | |
| 11_C | 23_C | 1.864 | 1.00 | |
| 11_C | 26_C | 1.848 | 1.00 | |
| 142_S | 147_C | 1.818 | 1.00 | |
| 72_P | 75_S | 1.777 | 1.00 | |
| 121_L | 132_N | 1.745 | 1.00 | |
| 211_L | 218_V | 1.738 | 1.00 | |
| 197_V | 203_V | 1.712 | 1.00 | |
| 191_V | 221_W | 1.706 | 1.00 | |
| 115_R | 190_M | 1.697 | 1.00 | |
| 150_D | 153_A | 1.682 | 1.00 | |
| 37_C | 51_C | 1.659 | 1.00 | |
| 215_A | 218_V | 1.64 | 1.00 | |
| 121_L | 125_R | 1.62 | 1.00 | |
| 201_S | 205_E | 1.607 | 1.00 | |
| 125_R | 156_R | 1.602 | 1.00 | |
| 116_I | 141_L | 1.586 | 1.00 | |
| 116_I | 142_S | 1.56 | 1.00 | |
| 134_S | 138_C | 1.553 | 1.00 | |
| 70_Y | 79_H | 1.509 | 1.00 | |
| 81_L | 90_A | 1.474 | 0.99 | |
| 123_Q | 127_W | 1.469 | 0.99 | |
| 8_C | 26_C | 1.434 | 0.99 | |
| 210_L | 215_A | 1.428 | 0.99 | |
| 115_R | 150_D | 1.418 | 0.99 | |
| 125_R | 128_R | 1.407 | 0.99 | |
| 138_C | 149_W | 1.407 | 0.99 | |
| 206_I | 209_L | 1.393 | 0.99 | |
| 155_T | 180_R | 1.378 | 0.99 | |
| 160_T | 178_A | 1.361 | 0.99 | |
| 93_L | 223_L | 1.36 | 0.99 | |
| 189_H | 219_Q | 1.352 | 0.99 | |
| 119_V | 202_T | 1.351 | 0.99 | |
| 117_V | 153_A | 1.348 | 0.99 | |
| 64_L | 222_C | 1.342 | 0.99 | |
| 8_C | 23_C | 1.338 | 0.99 | |
| 125_R | 133_Q | 1.329 | 0.98 | |
| 37_C | 54_C | 1.328 | 0.98 | |
| 113_P | 191_V | 1.326 | 0.98 | |
| 121_L | 156_R | 1.306 | 0.98 | |
| 62_Q | 217_A | 1.304 | 0.98 | |
| 97_L | 223_L | 1.302 | 0.98 | |
| 187_G | 215_A | 1.293 | 0.98 | |
| 163_Q | 179_F | 1.281 | 0.98 | |
| 95_R | 144_W | 1.273 | 0.98 | |
| 124_R | 159_A | 1.27 | 0.98 | |
| 207_A | 220_V | 1.254 | 0.98 | |
| 70_Y | 224_C | 1.229 | 0.97 | |
| 203_V | 222_C | 1.217 | 0.97 | |
| 81_L | 137_L | 1.215 | 0.97 | |
| 90_A | 136_L | 1.212 | 0.97 | |
| 80_Q | 86_R | 1.201 | 0.97 | |
| 122_W | 125_R | 1.187 | 0.96 | |
| 94_S | 141_L | 1.172 | 0.96 | |
| 97_L | 137_L | 1.169 | 0.96 | |
| 81_L | 93_L | 1.164 | 0.96 | |
| 135_D | 139_Q | 1.164 | 0.96 | |
| 157_T | 180_R | 1.163 | 0.96 | |
| 164_H | 196_V | 1.157 | 0.96 | |
| 52_G | 55_L | 1.12 | 0.94 | |
| 176_K | 205_E | 1.117 | 0.94 | |
| 83_F | 125_R | 1.113 | 0.94 | |
| 114_D | 189_H | 1.111 | 0.94 | |
| 121_L | 134_S | 1.102 | 0.94 | |
| 185_V | 215_A | 1.1 | 0.94 | |
| 122_W | 159_A | 1.1 | 0.94 | |
| 116_I | 193_V | 1.091 | 0.93 | |
| 135_D | 151_S | 1.089 | 0.93 | |
| 154_V | 192_I | 1.088 | 0.93 | |
| 22_I | 77_L | 1.076 | 0.93 | |
| 75_S | 79_H | 1.073 | 0.93 | |
| 79_H | 83_F | 1.055 | 0.92 | |
| 214_G | 218_V | 1.055 | 0.92 | |
| 116_I | 149_W | 1.054 | 0.92 | |
| 83_F | 133_Q | 1.049 | 0.92 | |
| 190_M | 215_A | 1.041 | 0.91 | |
| 174_N | 178_A | 1.04 | 0.91 | |
| 97_L | 221_W | 1.039 | 0.91 | |
| 175_L | 178_A | 1.027 | 0.90 | |
| 121_L | 126_H | 1.011 | 0.89 | |
| 63_R | 219_Q | 1.007 | 0.89 | |
| 61_W | 220_V | 1.007 | 0.89 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1zn8A | 2 | 0.696 | 99.9 | 0.639 | Contact Map | 0.497 |
| 1ecfA | 2 | 0.8899 | 99.9 | 0.643 | Contact Map | 0.577 |
| 1wd5A | 1 | 0.5507 | 99.8 | 0.654 | Contact Map | 0.578 |
| 1vchA | 5 | 0.6652 | 99.8 | 0.658 | Contact Map | 0.617 |
| 2dy0A | 2 | 0.7181 | 99.8 | 0.658 | Contact Map | 0.552 |
| 3dahA | 3 | 0.8767 | 99.8 | 0.663 | Contact Map | 0.456 |
| 1yfzA | 2 | 0.674 | 99.8 | 0.664 | Contact Map | 0.642 |
| 1u9yA | 4 | 0.8678 | 99.8 | 0.665 | Contact Map | 0.327 |
| 1y0bA | 4 | 0.6784 | 99.8 | 0.666 | Contact Map | 0.552 |
| 3lrtA | 2 | 0.8767 | 99.8 | 0.667 | Contact Map | 0.262 |
Sequence Conservation (Image Generated using WebLogo v3)