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OPENSEQ.org
OBG - GTPase ObgE/CgtA
UniProt: P42641 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12795
Length: 390 (336)
Sequences: 1725
Seq/Len: 5.13
OBG
Paralog alert: 0.02 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
48_E 114_R 4.717 1.00
46_W 116_L 4.433 1.00
22_S 35_D 3.64 1.00
263_I 278_R 3.588 1.00
106_G 115_L 3.571 1.00
49_A 108_M 3.464 1.00
179_V 211_V 3.442 1.00
177_R 186_V 3.377 1.00
15_D 69_R 3.285 1.00
49_A 92_V 3.227 1.00
98_D 150_R 3.221 1.00
59_Y 88_I 3.121 1.00
51_E 111_H 2.859 1.00
48_E 87_T 2.761 1.00
125_L 142_T 2.732 1.00
97_I 153_L 2.707 1.00
74_A 78_C 2.657 1.00
50_D 89_K 2.613 1.00
48_E 89_K 2.525 1.00
97_I 104_T 2.524 1.00
122_W 145_T 2.481 1.00
12_V 149_K 2.44 1.00
264_S 267_E 2.382 1.00
178_A 318_G 2.38 1.00
242_L 328_V 2.36 1.00
311_Y 327_D 2.331 1.00
69_R 72_N 2.287 1.00
38_D 129_R 2.268 1.00
264_S 268_K 2.255 1.00
109_T 113_Q 2.248 1.00
68_E 84_K 2.236 1.00
47_M 96_V 2.139 1.00
68_E 83_G 2.13 1.00
175_F 179_V 2.12 1.00
11_V 152_L 2.118 1.00
10_L 151_E 2.113 1.00
245_I 259_A 2.108 1.00
309_K 327_D 2.094 1.00
298_K 302_E 2.086 1.00
71_Q 74_A 2.066 1.00
243_H 262_I 2.032 1.00
46_W 114_R 2.009 1.00
21_V 141_K 1.963 1.00
12_V 15_D 1.961 1.00
95_R 104_T 1.948 1.00
175_F 244_L 1.931 1.00
15_D 18_N 1.93 1.00
100_G 151_E 1.906 1.00
41_D 82_R 1.905 1.00
77_D 128_T 1.904 1.00
157_M 236_E 1.893 1.00
283_N 315_A 1.886 1.00
135_N 140_Q 1.883 1.00
217_L 229_I 1.863 1.00
175_F 211_V 1.86 1.00
285_I 312_L 1.857 1.00
201_V 209_F 1.841 1.00
87_T 114_R 1.818 1.00
175_F 324_L 1.806 1.00
41_D 44_D 1.783 1.00
110_K 113_Q 1.746 1.00
222_A 268_K 1.744 1.00
24_R 29_I 1.684 1.00
313_I 324_L 1.65 0.99
244_L 283_N 1.63 0.99
207_K 333_I 1.527 0.99
11_V 45_V 1.522 0.99
296_K 299_A 1.506 0.99
165_L 241_L 1.501 0.99
44_D 116_L 1.482 0.98
271_Q 274_A 1.476 0.98
44_D 119_K 1.469 0.98
289_D 292_E 1.442 0.98
162_V 240_V 1.418 0.98
15_D 146_P 1.416 0.98
20_C 75_S 1.398 0.97
322_K 326_W 1.394 0.97
68_E 81_K 1.375 0.97
327_D 330_T 1.375 0.97
252_G 258_N 1.367 0.97
270_S 274_A 1.358 0.97
13_A 45_V 1.356 0.97
330_T 334_E 1.35 0.97
44_D 85_D 1.347 0.97
59_Y 65_F 1.346 0.97
98_D 101_T 1.345 0.97
240_V 328_V 1.341 0.97
240_V 331_F 1.325 0.96
176_I 180_S 1.323 0.96
259_A 263_I 1.304 0.96
179_V 325_C 1.295 0.96
257_E 261_I 1.294 0.96
246_D 283_N 1.292 0.95
10_L 149_K 1.29 0.95
299_A 303_A 1.289 0.95
242_L 281_V 1.287 0.95
20_C 74_A 1.286 0.95
47_M 117_V 1.282 0.95
167_M 261_I 1.274 0.95
8_S 151_E 1.27 0.95
13_A 118_A 1.263 0.95
12_V 66_R 1.259 0.95
99_Q 153_L 1.256 0.94
47_M 88_I 1.248 0.94
170_A 190_P 1.245 0.94
253_T 258_N 1.244 0.94
254_D 257_E 1.243 0.94
18_N 72_N 1.201 0.93
26_E 29_I 1.188 0.92
281_V 324_L 1.186 0.92
169_N 188_D 1.18 0.92
203_M 326_W 1.171 0.91
280_L 310_Y 1.157 0.91
46_W 87_T 1.156 0.91
256_V 260_R 1.156 0.91
204_D 326_W 1.154 0.91
311_Y 320_G 1.152 0.90
41_D 123_H 1.143 0.90
98_D 103_E 1.143 0.90
320_G 323_D 1.139 0.90
164_M 211_V 1.129 0.89
10_L 64_S 1.109 0.88
49_A 112_G 1.105 0.88
230_R 233_K 1.105 0.88
8_S 99_Q 1.099 0.87
239_R 332_I 1.094 0.87
180_S 211_V 1.089 0.87
167_M 253_T 1.085 0.87
6_E 233_K 1.075 0.86
119_K 148_D 1.071 0.86
142_T 145_T 1.067 0.85
162_V 332_I 1.066 0.85
79_T 82_R 1.063 0.85
259_A 308_D 1.056 0.84
163_G 241_L 1.052 0.84
165_L 235_L 1.052 0.84
79_T 129_R 1.052 0.84
47_M 152_L 1.051 0.84
282_F 312_L 1.047 0.84
247_I 285_I 1.04 0.83
24_R 30_P 1.039 0.83
117_V 152_L 1.034 0.83
299_A 302_E 1.033 0.83
43_G 67_A 1.027 0.82
279_W 328_V 1.023 0.82
122_W 142_T 1.016 0.81
45_V 67_A 1.012 0.81
229_I 233_K 1.01 0.81
125_L 129_R 1.007 0.80
6_E 230_R 1.005 0.80
98_D 105_M 1.003 0.80
281_V 313_I 1.001 0.80
287_L 316_A 1 0.80
95_R 157_M 1 0.80
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1lnzA20.87691000.346Contact Map0.833
1udxA10.95641000.377Contact Map0.748
3gehA10.86921000.777Contact Map0.411
3geeA10.88461000.785Contact Map0.483
1wxqA10.55641000.787Contact Map0.663
2dbyA10.56921000.82Contact Map0.469
3lvqE10.76671000.827Contact Map0.588
1ni3A10.60511000.827Contact Map0.499
4a9aA20.697499.90.832Contact Map0.75
2ohfA10.623199.90.833Contact Map0.504
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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