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OPENSEQ.org
YJIM - Uncharacterized protein YjiM
UniProt: P39384 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12574
Length: 383 (379)
Sequences: 602
Seq/Len: 1.59
YJIM
Paralog alert: 0.23 [within 20: 0.15] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
182_N 227_R 4.974 1.00
175_R 220_D 3.668 1.00
179_A 220_D 3.614 1.00
143_K 291_D 3.011 1.00
243_L 324_V 2.607 1.00
168_D 171_A 2.454 1.00
52_G 165_A 2.436 1.00
51_A 161_I 2.405 1.00
228_Q 232_E 2.404 1.00
150_Q 161_I 2.36 1.00
27_D 31_R 2.319 1.00
320_E 353_H 2.23 0.99
317_Q 321_E 2.225 0.99
143_K 147_L 2.173 0.99
165_A 168_D 2.164 0.99
139_R 295_D 2.123 0.99
313_K 317_Q 2.098 0.99
68_E 71_K 2.092 0.99
269_G 324_V 2.086 0.99
172_L 213_E 2.015 0.98
371_Q 374_T 1.975 0.98
319_V 355_I 1.973 0.98
78_C 335_C 1.958 0.98
28_L 33_I 1.916 0.98
40_C 273_C 1.912 0.97
168_D 213_E 1.911 0.97
103_V 149_L 1.842 0.97
188_Q 321_E 1.807 0.96
49_M 169_A 1.807 0.96
220_D 224_A 1.797 0.96
47_I 153_V 1.732 0.95
170_I 174_N 1.73 0.95
78_C 108_C 1.726 0.95
265_G 380_I 1.725 0.95
37_G 297_Y 1.715 0.94
8_P 11_F 1.694 0.94
348_H 352_Q 1.624 0.92
175_R 178_R 1.622 0.92
190_N 323_Q 1.565 0.90
152_T 155_E 1.562 0.90
316_S 348_H 1.543 0.89
120_E 347_R 1.525 0.88
358_I 376_V 1.509 0.88
228_Q 231_E 1.504 0.87
7_L 11_F 1.482 0.86
348_H 353_H 1.474 0.86
316_S 353_H 1.474 0.86
196_G 261_E 1.473 0.86
123_P 156_R 1.468 0.86
70_E 82_K 1.441 0.84
108_C 335_C 1.44 0.84
150_Q 290_Y 1.434 0.84
179_A 216_I 1.431 0.84
187_G 270_Y 1.406 0.82
45_Q 212_K 1.399 0.82
314_M 317_Q 1.373 0.80
370_G 373_S 1.364 0.80
171_A 323_Q 1.354 0.79
179_A 223_T 1.353 0.79
36_V 101_L 1.344 0.78
188_Q 322_Y 1.341 0.78
40_C 302_C 1.333 0.77
155_E 168_D 1.331 0.77
48_P 53_A 1.325 0.77
375_R 378_A 1.324 0.77
260_I 328_V 1.322 0.76
378_A 381_E 1.318 0.76
142_W 146_M 1.317 0.76
154_E 160_E 1.313 0.76
125_H 152_T 1.307 0.75
27_D 30_E 1.306 0.75
182_N 223_T 1.302 0.75
182_N 220_D 1.298 0.75
36_V 153_V 1.29 0.74
127_M 142_W 1.288 0.74
81_I 110_G 1.287 0.74
143_K 290_Y 1.287 0.74
172_L 216_I 1.276 0.73
151_K 155_E 1.267 0.72
29_K 100_D 1.265 0.72
171_A 285_E 1.265 0.72
315_L 319_V 1.256 0.71
28_L 31_R 1.255 0.71
273_C 302_C 1.249 0.71
375_R 381_E 1.246 0.70
182_N 185_H 1.237 0.69
113_K 116_E 1.236 0.69
72_D 89_K 1.234 0.69
258_R 262_E 1.228 0.69
316_S 320_E 1.227 0.69
23_L 27_D 1.224 0.68
185_H 188_Q 1.223 0.68
16_E 20_T 1.222 0.68
136_D 140_A 1.22 0.68
150_Q 163_E 1.217 0.68
182_N 224_A 1.216 0.68
160_E 165_A 1.215 0.67
37_G 58_L 1.21 0.67
371_Q 381_E 1.209 0.67
150_Q 154_E 1.208 0.67
162_S 165_A 1.198 0.66
168_D 172_L 1.194 0.66
140_A 291_D 1.188 0.65
319_V 327_V 1.187 0.65
243_L 327_V 1.185 0.65
175_R 179_A 1.183 0.64
178_R 282_C 1.176 0.64
49_M 173_K 1.168 0.63
74_P 80_L 1.165 0.63
326_G 379_F 1.165 0.63
374_T 378_A 1.164 0.63
255_K 368_D 1.161 0.62
195_S 198_D 1.151 0.61
130_P 335_C 1.149 0.61
136_D 352_Q 1.147 0.61
241_R 268_V 1.145 0.61
66_I 69_A 1.142 0.60
140_A 144_A 1.142 0.60
40_C 111_K 1.135 0.60
272_N 277_K 1.133 0.60
34_P 159_H 1.13 0.59
175_R 216_I 1.129 0.59
181_A 282_C 1.127 0.59
76_N 334_A 1.127 0.59
224_A 228_Q 1.122 0.58
144_A 171_A 1.122 0.58
186_L 223_T 1.12 0.58
370_G 374_T 1.118 0.58
374_T 381_E 1.117 0.58
349_V 355_I 1.113 0.57
7_L 22_F 1.113 0.57
144_A 147_L 1.105 0.57
125_H 149_L 1.101 0.56
79_P 381_E 1.095 0.56
150_Q 166_L 1.095 0.56
155_E 231_E 1.095 0.56
68_E 90_T 1.093 0.55
9_A 12_D 1.085 0.55
147_L 151_K 1.084 0.54
170_I 293_L 1.082 0.54
178_R 323_Q 1.08 0.54
128_Q 141_L 1.077 0.54
26_M 30_E 1.077 0.54
99_S 211_D 1.075 0.54
184_Y 279_T 1.071 0.53
269_G 322_Y 1.069 0.53
42_F 302_C 1.064 0.52
113_K 248_P 1.057 0.52
47_I 321_E 1.053 0.51
158_G 347_R 1.051 0.51
342_S 359_A 1.051 0.51
73_L 79_P 1.049 0.51
147_L 225_R 1.044 0.50
319_V 324_V 1.04 0.50
21_G 95_Y 1.04 0.50
10_I 15_S 1.039 0.50
315_L 345_I 1.038 0.50
74_P 107_T 1.036 0.49
176_E 216_I 1.036 0.49
52_G 221_A 1.032 0.49
33_I 52_G 1.03 0.49
154_E 161_I 1.028 0.49
336_H 339_A 1.027 0.48
83_S 87_F 1.023 0.48
221_A 324_V 1.022 0.48
239_R 262_E 1.019 0.48
260_I 265_G 1.01 0.47
242_I 326_G 1.009 0.47
192_P 266_W 1.009 0.47
139_R 294_A 1.006 0.46
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3o3mA20.97131000.244Contact Map0.565
3o3mB20.95561000.27Contact Map0.611
2vpqA20.331670.80.958Contact Map0.606
2pn1A10.32968.80.958Contact Map0.676
1w96A30.467464.60.96Contact Map0.585
3n6rA60.331662.60.96Contact Map0.534
1ulzA10.331654.50.962Contact Map0.695
3ouzA20.34253.10.962Contact Map0.666
2w70A20.334251.60.963Contact Map0.743
4h4dA20.441349.90.963Contact Map0.246
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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