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OPENSEQ.org

SGCQ - Putative sgc region protein SgcQ
UniProt: P39364 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12555
Length: 268 (267)
Sequences: 300
Seq/Len: 1.12

SGCQ
Paralog alert: 0.04 [within 20: 0.01] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
52_G 256_V 2.815 1.00
171_C 204_R 2.098 0.97
8_I 13_A 2.091 0.97
206_K 233_D 1.897 0.95
83_I 96_V 1.891 0.95
81_R 85_Q 1.839 0.93
244_D 249_N 1.818 0.93
155_F 183_P 1.809 0.93
100_W 127_S 1.747 0.91
206_K 214_V 1.743 0.91
216_A 220_V 1.734 0.91
107_D 142_H 1.632 0.87
14_V 235_C 1.596 0.85
99_L 119_E 1.593 0.85
260_M 263_V 1.555 0.83
43_W 90_I 1.55 0.83
21_R 42_A 1.543 0.82
20_L 42_A 1.539 0.82
60_S 218_T 1.513 0.80
45_D 251_V 1.508 0.80
54_V 241_F 1.506 0.80
160_E 218_T 1.417 0.74
14_V 54_V 1.403 0.73
22_A 214_V 1.397 0.73
135_N 138_E 1.396 0.72
121_F 139_T 1.386 0.72
85_Q 237_T 1.382 0.71
226_E 262_K 1.379 0.71
60_S 160_E 1.366 0.70
67_Y 119_E 1.363 0.70
100_W 119_E 1.362 0.70
5_K 11_E 1.36 0.70
185_A 215_L 1.355 0.69
241_F 260_M 1.339 0.68
174_A 209_V 1.339 0.68
158_V 162_A 1.331 0.67
40_D 152_K 1.326 0.67
54_V 256_V 1.318 0.66
26_D 64_S 1.308 0.65
100_W 180_N 1.299 0.64
60_S 193_A 1.294 0.64
77_A 106_F 1.293 0.64
154_L 185_A 1.292 0.64
174_A 205_V 1.291 0.64
110_M 147_G 1.288 0.63
187_C 217_N 1.285 0.63
119_E 159_P 1.277 0.62
40_D 44_D 1.264 0.61
7_V 87_M 1.255 0.61
87_M 225_V 1.251 0.60
226_E 257_S 1.25 0.60
101_D 120_I 1.25 0.60
17_M 58_M 1.237 0.59
49_L 189_S 1.236 0.59
101_D 104_A 1.229 0.58
85_Q 240_T 1.229 0.58
64_S 161_A 1.224 0.58
45_D 63_F 1.222 0.57
123_G 129_F 1.214 0.57
99_L 128_D 1.204 0.56
38_V 78_A 1.194 0.55
211_D 264_H 1.19 0.54
123_G 128_D 1.186 0.54
146_I 151_V 1.178 0.53
85_Q 88_S 1.178 0.53
35_M 78_A 1.176 0.53
129_F 180_N 1.17 0.53
57_V 112_T 1.17 0.53
120_I 129_F 1.161 0.52
62_E 159_P 1.153 0.51
100_W 129_F 1.148 0.50
122_T 177_T 1.147 0.50
5_K 14_V 1.145 0.50
98_V 108_L 1.141 0.50
28_S 182_H 1.14 0.50
119_E 129_F 1.134 0.49
47_M 89_D 1.132 0.49
48_A 52_G 1.126 0.48
17_M 189_S 1.125 0.48
197_T 202_L 1.124 0.48
159_P 193_A 1.123 0.48
56_A 73_P 1.119 0.48
156_N 218_T 1.113 0.47
238_A 266_I 1.111 0.47
83_I 94_F 1.11 0.47
60_S 161_A 1.108 0.47
97_N 119_E 1.106 0.46
35_M 53_G 1.105 0.46
185_A 234_G 1.101 0.46
197_T 220_V 1.097 0.46
60_S 159_P 1.097 0.46
144_H 149_G 1.088 0.45
91_R 185_A 1.086 0.45
156_N 217_N 1.086 0.45
100_W 159_P 1.085 0.44
84_G 238_A 1.082 0.44
99_L 236_V 1.079 0.44
200_A 254_A 1.078 0.44
157_I 174_A 1.076 0.44
10_T 13_A 1.067 0.43
57_V 90_I 1.061 0.42
198_D 244_D 1.061 0.42
99_L 129_F 1.061 0.42
205_V 214_V 1.06 0.42
153_T 237_T 1.057 0.42
196_R 224_N 1.056 0.42
120_I 123_G 1.054 0.42
57_V 196_R 1.05 0.41
77_A 111_A 1.043 0.40
21_R 41_K 1.043 0.40
161_A 218_T 1.042 0.40
17_M 49_L 1.04 0.40
141_R 154_L 1.039 0.40
21_R 38_V 1.039 0.40
64_S 193_A 1.035 0.40
125_Y 162_A 1.031 0.39
170_I 174_A 1.03 0.39
62_E 180_N 1.03 0.39
60_S 187_C 1.026 0.39
60_S 156_N 1.024 0.39
222_L 240_T 1.024 0.39
14_V 145_R 1.017 0.38
249_N 255_R 1.015 0.38
94_F 113_G 1.015 0.38
4_L 177_T 1.01 0.37
45_D 245_G 1.008 0.37
61_N 242_K 1.003 0.37
93_P 194_G 1.003 0.37
52_G 255_R 1.003 0.37
54_V 59_F 1.003 0.37
251_V 256_V 1.002 0.37
17_M 232_A 1.001 0.37
60_S 194_G 1.001 0.37
62_E 160_E 1.001 0.37
194_G 218_T 1 0.37
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1ujpA10.824699.80.801Contact Map0.274
3vndA80.858299.80.801Contact Map0.292
2ekcA20.850799.80.801Contact Map0.333
3thaA20.835899.80.805Contact Map0.291
3navA20.861999.80.807Contact Map0.259
1qopA10.861999.80.808Contact Map0.274
1rd5A20.854599.70.814Contact Map0.319
1geqA20.820999.70.818Contact Map0.31
2yw3A60.753799.70.82Contact Map0.362
3igsA20.779999.60.833Contact Map0.316

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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