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OPENSEQ.org
YJGR - Uncharacterized protein YjgR
UniProt: P39342 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12537
Length: 500 (495)
Sequences: 514
Seq/Len: 1.04
YJGR
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
152_K 418_Y 3.118 1.00
339_Q 350_E 2.854 1.00
64_T 97_V 2.802 1.00
386_R 394_E 2.774 1.00
149_L 414_R 2.727 1.00
152_K 413_D 2.539 0.99
391_T 394_E 2.478 0.99
253_A 256_L 2.454 0.99
43_L 319_V 2.431 0.99
93_N 220_I 2.331 0.99
415_E 423_K 2.215 0.98
103_E 227_K 2.204 0.98
313_G 330_D 2.198 0.98
326_F 330_D 2.182 0.98
75_K 78_A 2.126 0.97
351_K 355_E 2.118 0.97
69_A 92_A 2.107 0.97
74_E 78_A 2.05 0.96
367_D 371_S 2.041 0.96
472_Q 476_K 2.018 0.96
19_P 50_I 2.007 0.96
68_Q 390_V 1.998 0.96
486_I 494_L 1.966 0.95
113_S 147_L 1.925 0.95
137_I 161_I 1.901 0.94
114_D 203_M 1.858 0.93
473_T 476_K 1.854 0.93
97_V 398_L 1.827 0.92
205_D 407_K 1.818 0.92
66_V 220_I 1.799 0.91
413_D 418_Y 1.789 0.91
48_S 94_P 1.782 0.91
134_L 154_L 1.761 0.90
467_K 472_Q 1.749 0.90
480_R 484_N 1.748 0.90
164_N 167_S 1.727 0.89
468_D 472_Q 1.716 0.89
74_E 77_L 1.71 0.88
213_D 217_K 1.702 0.88
330_D 340_T 1.68 0.87
68_Q 394_E 1.675 0.87
348_D 351_K 1.67 0.87
106_H 406_G 1.647 0.86
357_G 369_K 1.631 0.85
487_V 490_M 1.631 0.85
396_N 400_N 1.626 0.85
209_W 242_M 1.586 0.83
406_G 409_E 1.585 0.83
273_N 281_D 1.585 0.83
113_S 142_D 1.58 0.83
55_F 223_L 1.568 0.82
243_L 297_V 1.565 0.82
247_Y 286_V 1.564 0.82
175_I 195_A 1.54 0.80
104_K 392_E 1.54 0.80
337_A 344_N 1.526 0.79
139_R 192_Q 1.525 0.79
285_Q 375_V 1.522 0.79
131_S 175_I 1.514 0.79
319_V 365_F 1.5 0.78
326_F 340_T 1.5 0.78
301_S 307_I 1.494 0.77
488_R 492_G 1.488 0.77
49_E 93_N 1.484 0.77
250_L 295_V 1.482 0.77
137_I 158_T 1.471 0.76
139_R 143_D 1.461 0.75
386_R 390_V 1.454 0.75
162_G 180_V 1.441 0.74
179_S 182_A 1.431 0.73
162_G 170_N 1.43 0.73
67_A 390_V 1.427 0.73
83_I 378_A 1.415 0.72
49_E 91_H 1.41 0.71
142_D 488_R 1.41 0.71
45_E 93_N 1.398 0.70
56_M 59_V 1.391 0.70
66_V 95_V 1.39 0.70
263_F 271_L 1.389 0.70
397_G 401_H 1.388 0.70
305_S 329_K 1.388 0.70
7_I 380_V 1.379 0.69
8_A 378_A 1.373 0.68
390_V 394_E 1.371 0.68
49_E 217_K 1.366 0.68
468_D 476_K 1.362 0.68
480_R 483_T 1.36 0.67
393_D 396_N 1.356 0.67
41_Q 388_G 1.348 0.66
142_D 145_G 1.338 0.66
42_K 381_I 1.334 0.65
470_V 476_K 1.33 0.65
8_A 381_I 1.33 0.65
133_V 175_I 1.33 0.65
39_T 380_V 1.323 0.64
474_M 478_A 1.322 0.64
337_A 353_I 1.316 0.64
132_G 188_L 1.31 0.63
106_H 409_E 1.301 0.62
78_A 82_N 1.298 0.62
147_L 420_M 1.292 0.62
312_L 357_G 1.291 0.61
28_I 68_Q 1.285 0.61
255_D 358_T 1.285 0.61
190_L 195_A 1.273 0.60
256_L 260_K 1.268 0.59
481_Q 485_Q 1.262 0.59
468_D 471_V 1.261 0.59
114_D 245_E 1.258 0.59
93_N 384_C 1.258 0.59
45_E 220_I 1.25 0.58
367_D 373_S 1.238 0.57
133_V 179_S 1.237 0.57
244_S 278_V 1.235 0.56
386_R 391_T 1.228 0.56
83_I 381_I 1.224 0.55
246_L 250_L 1.221 0.55
68_Q 386_R 1.22 0.55
390_V 404_V 1.219 0.55
355_E 377_R 1.218 0.55
469_G 472_Q 1.218 0.55
334_V 353_I 1.213 0.54
22_A 47_L 1.206 0.54
124_L 195_A 1.205 0.54
126_L 183_I 1.201 0.53
140_I 175_I 1.199 0.53
140_I 206_I 1.197 0.53
149_L 415_E 1.192 0.52
210_M 295_V 1.192 0.52
230_Q 247_Y 1.189 0.52
108_V 263_F 1.187 0.52
73_S 76_L 1.186 0.52
467_K 476_K 1.185 0.52
193_Q 233_K 1.184 0.52
95_V 209_W 1.18 0.51
363_I 380_V 1.179 0.51
27_L 45_E 1.178 0.51
319_V 348_D 1.176 0.51
303_N 337_A 1.176 0.51
41_Q 65_G 1.17 0.50
365_F 373_S 1.168 0.50
415_E 420_M 1.164 0.50
430_E 434_N 1.161 0.49
10_T 233_K 1.155 0.49
106_H 404_V 1.147 0.48
107_P 126_L 1.144 0.48
110_A 203_M 1.144 0.48
142_D 413_D 1.143 0.48
239_L 318_R 1.137 0.47
21_M 367_D 1.137 0.47
329_K 333_A 1.136 0.47
55_F 288_R 1.135 0.47
341_M 375_V 1.133 0.47
40_L 63_L 1.132 0.47
172_Y 182_A 1.132 0.47
91_H 384_C 1.131 0.47
288_R 389_P 1.128 0.46
288_R 313_G 1.127 0.46
144_Q 164_N 1.121 0.46
309_D 329_K 1.12 0.46
160_Y 166_K 1.117 0.45
5_L 108_V 1.117 0.45
326_F 341_M 1.116 0.45
28_I 385_S 1.116 0.45
368_A 392_E 1.104 0.44
139_R 282_K 1.101 0.44
67_A 423_K 1.098 0.44
95_V 220_I 1.095 0.43
263_F 328_P 1.093 0.43
441_E 444_V 1.09 0.43
398_L 405_Y 1.084 0.42
329_K 340_T 1.083 0.42
40_L 44_A 1.081 0.42
73_S 77_L 1.08 0.42
481_Q 484_N 1.078 0.42
193_Q 301_S 1.075 0.42
112_V 424_G 1.074 0.41
473_T 477_S 1.074 0.41
488_R 491_L 1.074 0.41
282_K 285_Q 1.072 0.41
29_T 206_I 1.07 0.41
305_S 310_N 1.065 0.41
333_A 340_T 1.064 0.41
8_A 189_S 1.064 0.41
77_L 81_K 1.06 0.40
8_A 379_M 1.059 0.40
113_S 489_G 1.057 0.40
114_D 193_Q 1.057 0.40
329_K 339_Q 1.055 0.40
76_L 80_L 1.055 0.40
46_S 49_E 1.055 0.40
142_D 245_E 1.052 0.39
487_V 494_L 1.05 0.39
56_M 385_S 1.05 0.39
4_P 19_P 1.05 0.39
18_L 368_A 1.047 0.39
48_S 398_L 1.046 0.39
55_F 102_G 1.045 0.39
347_F 374_V 1.041 0.38
27_L 247_Y 1.04 0.38
112_V 354_Q 1.04 0.38
230_Q 282_K 1.039 0.38
69_A 128_D 1.038 0.38
147_L 341_M 1.031 0.38
129_V 347_F 1.031 0.38
97_V 395_R 1.03 0.37
463_R 468_D 1.028 0.37
474_M 477_S 1.027 0.37
111_T 201_E 1.025 0.37
102_G 389_P 1.025 0.37
347_F 358_T 1.025 0.37
134_L 220_I 1.023 0.37
80_L 382_A 1.021 0.37
38_V 387_M 1.01 0.36
365_F 376_E 1.009 0.36
178_A 300_V 1.006 0.35
253_A 260_K 1.005 0.35
97_V 375_V 1.003 0.35
380_V 435_P 1.003 0.35
287_I 363_I 1.001 0.35
356_L 363_I 1 0.35
348_D 430_E 1 0.35
50_I 301_S 1 0.35
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4ag6A40.7021000.885Contact Map0.228
1e9rA60.70499.90.9Contact Map0.23
2iusA60.67299.60.932Contact Map0.347
2iutA20.70299.10.947Contact Map0.352
2r2aA20.34298.70.955Contact Map0.366
1d2nA10.426980.963Contact Map0.116
1jbkA10.33697.80.964Contact Map0.154
2qbyA10.63697.80.965Contact Map0.216
4b4tL10.45897.80.965Contact Map0.189
2c9oA30.70497.80.965Contact Map0.081
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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