| UniProt: | P39172 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12678 | ||
| Length: | 310 (286) | ||
| Sequences: | 2595 | ||
| Seq/Len: | 9.07 |
| ZNUA
Paralog alert: 0.55 [within 20: 0.02] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 166_M | 173_L | 4.702 | 1.00 | |
| 152_R | 185_A | 4.674 | 1.00 | |
| 43_A | 47_T | 4.483 | 1.00 | |
| 46_V | 169_S | 4.356 | 1.00 | |
| 147_S | 216_Q | 4.263 | 1.00 | |
| 188_E | 217_F | 3.911 | 1.00 | |
| 190_Q | 297_S | 3.883 | 1.00 | |
| 159_H | 177_L | 3.591 | 1.00 | |
| 46_V | 172_K | 3.566 | 1.00 | |
| 169_S | 173_L | 3.432 | 1.00 | |
| 170_R | 174_D | 3.161 | 1.00 | |
| 166_M | 169_S | 2.963 | 1.00 | |
| 39_A | 79_V | 2.719 | 1.00 | |
| 159_H | 163_V | 2.682 | 1.00 | |
| 156_V | 181_E | 2.668 | 1.00 | |
| 163_V | 174_D | 2.498 | 1.00 | |
| 155_A | 177_L | 2.469 | 1.00 | |
| 27_A | 48_E | 2.456 | 1.00 | |
| 261_P | 265_E | 2.357 | 1.00 | |
| 41_A | 183_Q | 2.26 | 1.00 | |
| 152_R | 181_E | 2.247 | 1.00 | |
| 163_V | 170_R | 2.221 | 1.00 | |
| 39_A | 162_L | 2.215 | 1.00 | |
| 50_E | 71_R | 2.172 | 1.00 | |
| 36_G | 51_V | 2.147 | 1.00 | |
| 29_V | 75_A | 2.116 | 1.00 | |
| 38_I | 151_A | 2.051 | 1.00 | |
| 245_L | 271_T | 2.035 | 1.00 | |
| 42_I | 177_L | 2.029 | 1.00 | |
| 169_S | 172_K | 1.976 | 1.00 | |
| 188_E | 192_G | 1.958 | 1.00 | |
| 39_A | 158_I | 1.95 | 1.00 | |
| 194_E | 304_A | 1.916 | 1.00 | |
| 155_A | 180_F | 1.856 | 1.00 | |
| 191_V | 300_A | 1.787 | 1.00 | |
| 177_L | 181_E | 1.777 | 1.00 | |
| 244_Q | 248_Q | 1.711 | 1.00 | |
| 150_I | 153_A | 1.703 | 1.00 | |
| 179_D | 183_Q | 1.702 | 1.00 | |
| 149_E | 216_Q | 1.645 | 1.00 | |
| 36_G | 40_S | 1.636 | 1.00 | |
| 194_E | 301_N | 1.628 | 1.00 | |
| 175_A | 179_D | 1.628 | 1.00 | |
| 161_K | 165_L | 1.596 | 1.00 | |
| 159_H | 174_D | 1.595 | 1.00 | |
| 243_T | 247_E | 1.581 | 1.00 | |
| 43_A | 162_L | 1.581 | 1.00 | |
| 183_Q | 297_S | 1.576 | 1.00 | |
| 46_V | 166_M | 1.572 | 1.00 | |
| 77_L | 161_K | 1.541 | 1.00 | |
| 77_L | 165_L | 1.51 | 1.00 | |
| 38_I | 180_F | 1.498 | 1.00 | |
| 241_I | 267_V | 1.494 | 1.00 | |
| 68_D | 71_R | 1.465 | 1.00 | |
| 237_R | 240_E | 1.464 | 1.00 | |
| 178_K | 182_A | 1.451 | 1.00 | |
| 213_F | 300_A | 1.441 | 0.99 | |
| 153_A | 157_A | 1.426 | 0.99 | |
| 202_G | 220_T | 1.423 | 0.99 | |
| 190_Q | 194_E | 1.399 | 0.99 | |
| 174_D | 178_K | 1.398 | 0.99 | |
| 38_I | 155_A | 1.393 | 0.99 | |
| 28_V | 162_L | 1.385 | 0.99 | |
| 41_A | 180_F | 1.371 | 0.99 | |
| 291_S | 294_E | 1.361 | 0.99 | |
| 297_S | 301_N | 1.359 | 0.99 | |
| 279_D | 282_G | 1.357 | 0.99 | |
| 42_I | 155_A | 1.354 | 0.99 | |
| 204_F | 245_L | 1.351 | 0.99 | |
| 156_V | 159_H | 1.343 | 0.99 | |
| 144_L | 154_T | 1.342 | 0.99 | |
| 161_K | 164_E | 1.336 | 0.99 | |
| 183_Q | 293_S | 1.323 | 0.99 | |
| 152_R | 156_V | 1.319 | 0.99 | |
| 141_N | 211_G | 1.294 | 0.99 | |
| 290_T | 294_E | 1.292 | 0.99 | |
| 201_K | 218_G | 1.286 | 0.99 | |
| 67_S | 70_K | 1.285 | 0.99 | |
| 27_A | 76_D | 1.279 | 0.98 | |
| 239_H | 243_T | 1.274 | 0.98 | |
| 191_V | 296_L | 1.27 | 0.98 | |
| 172_K | 176_N | 1.264 | 0.98 | |
| 44_D | 172_K | 1.26 | 0.98 | |
| 242_R | 267_V | 1.251 | 0.98 | |
| 214_E | 219_L | 1.247 | 0.98 | |
| 171_A | 174_D | 1.247 | 0.98 | |
| 192_G | 196_A | 1.245 | 0.98 | |
| 80_W | 89_M | 1.242 | 0.98 | |
| 60_H | 143_H | 1.241 | 0.98 | |
| 191_V | 213_F | 1.238 | 0.98 | |
| 265_E | 269_R | 1.236 | 0.98 | |
| 189_T | 193_N | 1.234 | 0.98 | |
| 245_L | 273_V | 1.228 | 0.98 | |
| 203_Y | 206_F | 1.213 | 0.98 | |
| 202_G | 248_Q | 1.205 | 0.98 | |
| 78_V | 89_M | 1.201 | 0.97 | |
| 171_A | 175_A | 1.2 | 0.97 | |
| 25_D | 48_E | 1.197 | 0.97 | |
| 109_D | 157_A | 1.195 | 0.97 | |
| 147_S | 150_I | 1.194 | 0.97 | |
| 149_E | 188_E | 1.194 | 0.97 | |
| 182_A | 185_A | 1.191 | 0.97 | |
| 28_V | 47_T | 1.187 | 0.97 | |
| 190_Q | 301_N | 1.185 | 0.97 | |
| 160_G | 163_V | 1.183 | 0.97 | |
| 186_S | 190_Q | 1.172 | 0.97 | |
| 221_P | 224_H | 1.169 | 0.97 | |
| 37_F | 180_F | 1.157 | 0.97 | |
| 81_V | 154_T | 1.147 | 0.96 | |
| 181_E | 185_A | 1.132 | 0.96 | |
| 183_Q | 186_S | 1.128 | 0.96 | |
| 281_L | 284_N | 1.127 | 0.96 | |
| 37_F | 41_A | 1.126 | 0.96 | |
| 26_A | 165_L | 1.109 | 0.95 | |
| 62_Y | 68_D | 1.106 | 0.95 | |
| 255_A | 275_M | 1.103 | 0.95 | |
| 38_I | 154_T | 1.1 | 0.95 | |
| 41_A | 293_S | 1.096 | 0.95 | |
| 27_A | 50_E | 1.078 | 0.94 | |
| 175_A | 178_K | 1.077 | 0.94 | |
| 64_L | 88_F | 1.076 | 0.94 | |
| 156_V | 160_G | 1.075 | 0.94 | |
| 278_L | 281_L | 1.043 | 0.93 | |
| 157_A | 161_K | 1.04 | 0.93 | |
| 223_G | 226_T | 1.032 | 0.93 | |
| 210_Y | 278_L | 1.031 | 0.93 | |
| 29_V | 71_R | 1.027 | 0.92 | |
| 79_V | 161_K | 1.019 | 0.92 | |
| 30_A | 39_A | 1.019 | 0.92 | |
| 180_F | 184_L | 1.011 | 0.92 | |
| 301_N | 305_S | 1.008 | 0.91 | |
| 208_D | 223_G | 1.006 | 0.91 | |
| 26_A | 43_A | 1 | 0.91 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2prsA | 2 | 0.9097 | 100 | 0.116 | Contact Map | 0.741 |
| 2o1eA | 2 | 0.9484 | 100 | 0.136 | Contact Map | 0.829 |
| 4k3vA | 2 | 0.9355 | 100 | 0.147 | Contact Map | 0.825 |
| 1pq4A | 2 | 0.8871 | 100 | 0.153 | Contact Map | 0.763 |
| 3gi1A | 2 | 0.9065 | 100 | 0.158 | Contact Map | 0.737 |
| 3cx3A | 2 | 0.9065 | 100 | 0.158 | Contact Map | 0.786 |
| 4h0fA | 2 | 0.8484 | 100 | 0.175 | Contact Map | 0.728 |
| 3ujpA | 3 | 0.8806 | 100 | 0.179 | Contact Map | 0.84 |
| 1toaA | 2 | 0.9355 | 100 | 0.183 | Contact Map | 0.793 |
| 3zk9A | 2 | 0.8645 | 100 | 0.185 | Contact Map | 0.805 |
Sequence Conservation (Image Generated using WebLogo v3)