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OPENSEQ.org
OGRK - Prophage P2 OGR protein
UniProt: P37057 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12425
Length: 72 (72)
Sequences: 96
Seq/Len: 1.33
OGRK
Paralog alert: 0.23 [within 20: 0.01] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
3_H 18_Y 2.868 1.00
40_I 47_R 2.057 0.98
37_A 48_Y 1.996 0.97
25_E 40_I 1.735 0.93
12_H 43_E 1.601 0.88
65_S 68_Q 1.543 0.86
3_H 26_R 1.523 0.85
43_E 52_P 1.52 0.85
8_Q 13_A 1.515 0.84
36_S 48_Y 1.5 0.84
3_H 28_H 1.5 0.84
24_K 43_E 1.369 0.75
12_H 49_I 1.368 0.75
11_A 26_R 1.338 0.73
23_T 45_V 1.329 0.72
24_K 52_P 1.287 0.69
2_F 41_T 1.277 0.68
3_H 17_R 1.258 0.66
64_P 71_W 1.248 0.65
68_Q 72_M 1.234 0.64
69_I 72_M 1.201 0.61
43_E 49_I 1.186 0.59
2_F 42_Y 1.163 0.57
34_N 49_I 1.15 0.56
6_L 23_T 1.139 0.55
12_H 24_K 1.138 0.55
8_Q 17_R 1.137 0.54
6_L 37_A 1.136 0.54
65_S 69_I 1.134 0.54
15_T 46_Q 1.123 0.53
57_V 62_P 1.118 0.53
12_H 52_P 1.106 0.51
12_H 18_Y 1.102 0.51
13_A 69_I 1.091 0.50
11_A 28_H 1.077 0.48
68_Q 71_W 1.07 0.48
28_H 41_T 1.047 0.45
14_R 19_I 1.043 0.45
50_V 53_G 1.007 0.42
2_F 46_Q 1.006 0.41
61_H 67_Q 1.006 0.41
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3ga8A10.87579.90.866Contact Map0.082
4kisA4179.30.867Contact Map0.09
1wjpA10.87579.20.867Contact Map0.201
1pqvS10.5139770.869Contact Map0
3po3S10.569.90.876Contact Map0.286
2hu9A20.902863.40.882Contact Map0.284
1p91A20.819461.40.883Contact Map0.172
1tfiA10.560.30.884Contact Map0.399
3zmsC10.861158.50.885Contact Map
4m9vC20.763957.90.885Contact Map0.136
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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