| UniProt: | P33644 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12097 | ||
| Length: | 243 (243) | ||
| Sequences: | 1540 | ||
| Seq/Len: | 6.34 |
| YFIH
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 161_A | 216_C | 3.491 | 1.00 | |
| 161_A | 219_T | 3.122 | 1.00 | |
| 111_L | 122_A | 3.034 | 1.00 | |
| 139_V | 149_I | 3.027 | 1.00 | |
| 90_A | 138_T | 2.97 | 1.00 | |
| 104_T | 238_S | 2.836 | 1.00 | |
| 49_E | 53_R | 2.719 | 1.00 | |
| 112_F | 123_A | 2.716 | 1.00 | |
| 123_A | 138_T | 2.627 | 1.00 | |
| 49_E | 52_K | 2.55 | 1.00 | |
| 162_F | 192_A | 2.459 | 1.00 | |
| 73_K | 137_E | 2.275 | 1.00 | |
| 108_L | 156_A | 2.241 | 1.00 | |
| 160_R | 219_T | 2.238 | 1.00 | |
| 166_G | 170_E | 2.212 | 1.00 | |
| 119_E | 142_F | 2.184 | 1.00 | |
| 112_F | 151_A | 2.158 | 1.00 | |
| 90_A | 123_A | 2.134 | 1.00 | |
| 29_P | 32_D | 2.103 | 1.00 | |
| 220_E | 223_T | 2.072 | 1.00 | |
| 112_F | 138_T | 2.063 | 1.00 | |
| 20_S | 54_L | 2.047 | 1.00 | |
| 110_V | 135_L | 2.034 | 1.00 | |
| 136_E | 201_R | 2.022 | 1.00 | |
| 130_L | 198_A | 2.018 | 1.00 | |
| 116_A | 148_N | 2.004 | 1.00 | |
| 34_L | 54_L | 1.959 | 1.00 | |
| 112_F | 149_I | 1.935 | 1.00 | |
| 158_G | 216_C | 1.935 | 1.00 | |
| 68_E | 87_R | 1.929 | 1.00 | |
| 158_G | 161_A | 1.905 | 1.00 | |
| 28_L | 46_H | 1.851 | 1.00 | |
| 33_S | 225_F | 1.848 | 1.00 | |
| 144_D | 149_I | 1.755 | 1.00 | |
| 109_P | 154_G | 1.704 | 1.00 | |
| 165_G | 168_V | 1.69 | 1.00 | |
| 114_N | 142_F | 1.679 | 1.00 | |
| 43_N | 46_H | 1.658 | 1.00 | |
| 196_Q | 199_R | 1.654 | 1.00 | |
| 151_A | 202_L | 1.617 | 1.00 | |
| 114_N | 242_L | 1.593 | 1.00 | |
| 15_V | 242_L | 1.568 | 0.99 | |
| 111_L | 238_S | 1.546 | 0.99 | |
| 215_R | 223_T | 1.539 | 0.99 | |
| 108_L | 198_A | 1.528 | 0.99 | |
| 156_A | 195_Y | 1.518 | 0.99 | |
| 157_I | 218_Y | 1.5 | 0.99 | |
| 139_V | 205_V | 1.499 | 0.99 | |
| 91_S | 100_C | 1.498 | 0.99 | |
| 92_Y | 142_F | 1.486 | 0.99 | |
| 215_R | 220_E | 1.473 | 0.99 | |
| 38_A | 48_E | 1.461 | 0.99 | |
| 99_V | 241_W | 1.461 | 0.99 | |
| 73_K | 132_A | 1.449 | 0.99 | |
| 195_Y | 212_G | 1.445 | 0.99 | |
| 125_A | 198_A | 1.442 | 0.99 | |
| 26_V | 46_H | 1.415 | 0.99 | |
| 44_P | 48_E | 1.413 | 0.99 | |
| 123_A | 135_L | 1.406 | 0.98 | |
| 114_N | 118_T | 1.403 | 0.98 | |
| 92_Y | 119_E | 1.398 | 0.98 | |
| 133_G | 136_E | 1.382 | 0.98 | |
| 199_R | 203_A | 1.361 | 0.98 | |
| 122_A | 240_I | 1.353 | 0.98 | |
| 26_V | 49_E | 1.336 | 0.98 | |
| 75_V | 137_E | 1.331 | 0.98 | |
| 114_N | 119_E | 1.328 | 0.98 | |
| 158_G | 219_T | 1.317 | 0.97 | |
| 76_L | 88_A | 1.315 | 0.97 | |
| 195_Y | 213_G | 1.306 | 0.97 | |
| 19_S | 238_S | 1.303 | 0.97 | |
| 139_V | 207_V | 1.292 | 0.97 | |
| 121_A | 138_T | 1.279 | 0.97 | |
| 137_E | 140_S | 1.272 | 0.97 | |
| 100_C | 120_V | 1.269 | 0.97 | |
| 163_E | 189_K | 1.266 | 0.97 | |
| 115_R | 148_N | 1.259 | 0.96 | |
| 169_R | 190_Y | 1.23 | 0.96 | |
| 67_L | 88_A | 1.228 | 0.96 | |
| 77_K | 94_N | 1.201 | 0.95 | |
| 115_R | 150_L | 1.201 | 0.95 | |
| 40_C | 233_T | 1.182 | 0.94 | |
| 93_S | 98_T | 1.171 | 0.94 | |
| 215_R | 224_F | 1.169 | 0.94 | |
| 101_A | 237_A | 1.157 | 0.93 | |
| 135_L | 198_A | 1.142 | 0.93 | |
| 134_V | 137_E | 1.138 | 0.93 | |
| 35_N | 42_D | 1.137 | 0.93 | |
| 119_E | 144_D | 1.137 | 0.93 | |
| 104_T | 122_A | 1.129 | 0.92 | |
| 120_V | 240_I | 1.119 | 0.92 | |
| 60_L | 99_V | 1.11 | 0.91 | |
| 216_C | 219_T | 1.105 | 0.91 | |
| 25_G | 42_D | 1.105 | 0.91 | |
| 112_F | 135_L | 1.104 | 0.91 | |
| 20_S | 239_F | 1.101 | 0.91 | |
| 227_Y | 230_D | 1.096 | 0.91 | |
| 169_R | 173_M | 1.095 | 0.91 | |
| 111_L | 240_I | 1.093 | 0.91 | |
| 19_S | 152_W | 1.087 | 0.90 | |
| 220_E | 224_F | 1.08 | 0.90 | |
| 78_L | 91_S | 1.072 | 0.89 | |
| 155_P | 217_T | 1.072 | 0.89 | |
| 108_L | 194_I | 1.067 | 0.89 | |
| 67_L | 91_S | 1.065 | 0.89 | |
| 125_A | 130_L | 1.062 | 0.89 | |
| 161_A | 218_Y | 1.06 | 0.89 | |
| 230_D | 233_T | 1.053 | 0.88 | |
| 27_S | 50_N | 1.05 | 0.88 | |
| 170_E | 174_A | 1.042 | 0.88 | |
| 199_R | 212_G | 1.04 | 0.88 | |
| 74_D | 87_R | 1.037 | 0.87 | |
| 196_Q | 200_Q | 1.036 | 0.87 | |
| 54_L | 239_F | 1.033 | 0.87 | |
| 157_I | 164_V | 1.031 | 0.87 | |
| 108_L | 153_L | 1.019 | 0.86 | |
| 131_C | 168_V | 1.014 | 0.86 | |
| 193_D | 196_Q | 1.012 | 0.86 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1z9tA | 1 | 0.9959 | 100 | -0.004 | Contact Map | 0.783 |
| 1rv9A | 1 | 0.9918 | 100 | 0.013 | Contact Map | 0.748 |
| 1xfjA | 1 | 1 | 100 | 0.021 | Contact Map | 0.781 |
| 1t8hA | 1 | 1 | 100 | 0.023 | Contact Map | 0.81 |
| 2f9zC | 2 | 0.5556 | 15.9 | 0.964 | Contact Map | 0.496 |
| 2hq2A | 1 | 0.4733 | 4.2 | 0.973 | Contact Map | 0.236 |
| 2j0pA | 1 | 0.4774 | 4.1 | 0.973 | Contact Map | 0.144 |
| 2ftcH | 1 | 0.5103 | 2.7 | 0.975 | Contact Map | 0.003 |
| 1np7A | 2 | 0.6337 | 2.3 | 0.976 | Contact Map | 0.208 |
| 4h31A | 3 | 0.7366 | 1.9 | 0.977 | Contact Map | 0.165 |
Sequence Conservation (Image Generated using WebLogo v3)