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OPENSEQ.org

RECX - Regulatory protein RecX
UniProt: P33596 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12080
Length: 166 (145)
Sequences: 1212
Seq/Len: 8.36

RECX
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
29_E 64_H 3.841 1.00
33_R 57_E 2.752 1.00
30_Q 34_R 2.665 1.00
145_R 149_Y 2.512 1.00
67_G 70_D 2.416 1.00
25_R 31_E 2.405 1.00
29_E 60_I 2.359 1.00
29_E 33_R 2.129 1.00
26_D 73_R 2.045 1.00
17_R 44_N 2.022 1.00
87_Y 91_R 2.014 1.00
97_N 103_R 1.931 1.00
125_A 143_I 1.9 1.00
89_P 117_W 1.863 1.00
15_L 62_W 1.844 1.00
27_H 35_K 1.803 1.00
82_R 95_E 1.764 1.00
14_L 59_V 1.715 1.00
25_R 74_F 1.69 1.00
91_R 95_E 1.686 1.00
90_A 93_R 1.594 1.00
141_V 145_R 1.585 1.00
144_Q 157_I 1.574 1.00
118_C 159_E 1.572 1.00
77_R 80_A 1.538 1.00
153_L 156_D 1.511 1.00
146_F 150_R 1.506 1.00
74_F 78_F 1.498 1.00
137_F 140_K 1.475 0.99
148_L 157_I 1.471 0.99
72_S 108_K 1.433 0.99
76_A 112_E 1.4 0.99
62_W 66_H 1.38 0.99
17_R 35_K 1.363 0.99
28_S 74_F 1.359 0.99
61_A 65_E 1.35 0.99
102_S 105_A 1.349 0.99
105_A 109_A 1.328 0.99
121_A 160_I 1.306 0.98
11_Y 58_R 1.289 0.98
29_E 61_A 1.276 0.98
118_C 156_D 1.267 0.98
75_V 101_I 1.262 0.98
21_I 32_L 1.258 0.98
60_I 64_H 1.236 0.98
29_E 69_L 1.229 0.98
18_A 63_C 1.188 0.97
34_R 43_K 1.187 0.97
78_F 99_K 1.181 0.97
24_V 27_H 1.172 0.96
72_S 76_A 1.147 0.96
94_Q 98_Q 1.143 0.96
64_H 69_L 1.137 0.96
16_D 20_R 1.131 0.95
35_K 43_K 1.119 0.95
27_H 31_E 1.102 0.94
121_A 156_D 1.099 0.94
73_R 76_A 1.091 0.94
14_L 46_P 1.09 0.94
26_D 77_R 1.088 0.94
78_F 82_R 1.083 0.94
128_K 131_E 1.082 0.94
75_V 109_A 1.078 0.94
28_S 101_I 1.067 0.93
21_I 27_H 1.065 0.93
144_Q 154_M 1.06 0.93
70_D 73_R 1.05 0.92
125_A 130_G 1.033 0.92
93_R 97_N 1.03 0.91
74_F 95_E 1.002 0.90
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3dfgA10.85541000.15Contact Map0.711
3c1dA20.86751000.154Contact Map0.713
3e3vA10.90361000.177Contact Map0.745
3d5lA20.92171000.192Contact Map0.685
4esfA10.602461.50.905Contact Map0.432
3tgnA20.722959.40.906Contact Map0.422
3tqnA30.548257.60.907Contact Map0.406
3ri2A20.626553.50.909Contact Map0.414
4fzvB10.578351.90.91Contact Map0.279
1xmaA20.614550.80.911Contact Map0.339

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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