| UniProt: | P33554 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12081 | ||
| Length: | 156 (154) | ||
| Sequences: | 768 | ||
| Seq/Len: | 4.99 |
| PPDA
Paralog alert: 0.18 [within 20: 0.07] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 56_D | 60_H | 2.784 | 1.00 | |
| 56_D | 59_W | 2.598 | 1.00 | |
| 40_W | 44_S | 2.557 | 1.00 | |
| 137_V | 145_R | 1.988 | 1.00 | |
| 53_L | 64_H | 1.948 | 1.00 | |
| 124_H | 135_W | 1.883 | 1.00 | |
| 81_A | 85_N | 1.844 | 1.00 | |
| 19_L | 23_S | 1.785 | 1.00 | |
| 6_G | 9_L | 1.704 | 1.00 | |
| 120_A | 138_V | 1.68 | 0.99 | |
| 68_V | 75_W | 1.669 | 0.99 | |
| 53_L | 66_I | 1.646 | 0.99 | |
| 76_C | 87_C | 1.639 | 0.99 | |
| 13_L | 19_L | 1.6 | 0.99 | |
| 67_S | 128_K | 1.6 | 0.99 | |
| 128_K | 133_E | 1.568 | 0.99 | |
| 97_P | 136_L | 1.564 | 0.99 | |
| 69_I | 72_G | 1.551 | 0.99 | |
| 136_L | 144_L | 1.529 | 0.99 | |
| 15_A | 18_I | 1.52 | 0.99 | |
| 40_W | 134_W | 1.465 | 0.98 | |
| 74_L | 78_V | 1.433 | 0.98 | |
| 39_L | 127_F | 1.415 | 0.98 | |
| 10_I | 14_V | 1.4 | 0.97 | |
| 65_S | 112_A | 1.389 | 0.97 | |
| 17_L | 20_V | 1.365 | 0.97 | |
| 45_Q | 49_Y | 1.357 | 0.97 | |
| 17_L | 62_R | 1.352 | 0.97 | |
| 15_A | 20_V | 1.339 | 0.96 | |
| 6_G | 11_E | 1.308 | 0.96 | |
| 24_A | 82_A | 1.268 | 0.95 | |
| 43_A | 134_W | 1.254 | 0.94 | |
| 49_Y | 53_L | 1.238 | 0.94 | |
| 128_K | 147_C | 1.237 | 0.94 | |
| 39_L | 43_A | 1.233 | 0.93 | |
| 65_S | 138_V | 1.212 | 0.93 | |
| 123_G | 135_W | 1.207 | 0.92 | |
| 121_W | 138_V | 1.194 | 0.92 | |
| 9_L | 18_I | 1.192 | 0.92 | |
| 115_G | 121_W | 1.191 | 0.92 | |
| 34_Q | 38_R | 1.182 | 0.91 | |
| 138_V | 142_G | 1.173 | 0.91 | |
| 8_T | 24_A | 1.167 | 0.91 | |
| 58_N | 117_R | 1.164 | 0.91 | |
| 21_M | 35_Q | 1.132 | 0.89 | |
| 34_Q | 37_Q | 1.124 | 0.88 | |
| 83_G | 91_S | 1.12 | 0.88 | |
| 62_R | 131_T | 1.113 | 0.88 | |
| 85_N | 88_H | 1.108 | 0.87 | |
| 50_L | 144_L | 1.105 | 0.87 | |
| 50_L | 111_L | 1.098 | 0.87 | |
| 80_S | 83_G | 1.097 | 0.87 | |
| 124_H | 143_R | 1.09 | 0.86 | |
| 37_Q | 44_S | 1.089 | 0.86 | |
| 69_I | 140_P | 1.088 | 0.86 | |
| 54_R | 120_A | 1.083 | 0.86 | |
| 32_Y | 36_S | 1.073 | 0.85 | |
| 123_G | 139_S | 1.072 | 0.85 | |
| 113_F | 144_L | 1.071 | 0.85 | |
| 77_L | 125_I | 1.068 | 0.85 | |
| 122_A | 128_K | 1.056 | 0.84 | |
| 25_S | 141_W | 1.051 | 0.83 | |
| 27_L | 105_S | 1.048 | 0.83 | |
| 68_V | 78_V | 1.039 | 0.82 | |
| 17_L | 22_L | 1.036 | 0.82 | |
| 138_V | 144_L | 1.024 | 0.81 | |
| 7_Y | 11_E | 1.02 | 0.81 | |
| 28_Y | 41_Q | 1.018 | 0.81 | |
| 50_L | 141_W | 1.011 | 0.80 | |
| 136_L | 143_R | 1.006 | 0.80 | |
| 10_I | 90_S | 1.005 | 0.80 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1oqwA | 2 | 0.8397 | 98.9 | 0.682 | Contact Map | 0.338 |
| 3sokA | 2 | 0.8397 | 98.5 | 0.728 | Contact Map | 0.319 |
| 2m7gA | 1 | 0.391 | 98.5 | 0.731 | Contact Map | 0.274 |
| 2hi2A | 1 | 0.7244 | 98.2 | 0.751 | Contact Map | 0.357 |
| 2knqA | 1 | 0.8013 | 96 | 0.824 | Contact Map | 0.337 |
| 4dq9A | 2 | 0.7821 | 96 | 0.825 | Contact Map | 0.571 |
| 3j27B | 3 | 0.1987 | 19.8 | 0.92 | Contact Map | 0.623 |
| 4azxD | 3 | 0.1987 | 19.7 | 0.92 | Contact Map | 0 |
| 4cbfB | 3 | 0.1923 | 16.5 | 0.923 | Contact Map | 0.037 |
| 2k1eA | 4 | 0.2564 | 3.9 | 0.942 | Contact Map | 0.384 |
Sequence Conservation (Image Generated using WebLogo v3)