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OPENSEQ.org
FLIR - Flagellar biosynthetic protein FliR
UniProt: P33135 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11977
Length: 261 (256)
Sequences: 1004
Seq/Len: 3.92
FLIR
Paralog alert: 0.33 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
198_N 221_T 3.752 1.00
21_L 74_A 3.088 1.00
25_A 78_I 2.851 1.00
152_D 155_H 2.789 1.00
137_F 142_G 2.429 1.00
115_D 118_S 2.274 1.00
27_I 50_I 2.234 1.00
92_F 137_F 1.993 1.00
40_K 43_K 1.931 1.00
103_G 221_T 1.891 1.00
95_V 133_A 1.857 1.00
106_M 225_G 1.824 1.00
125_L 229_M 1.808 0.99
97_T 183_G 1.808 0.99
141_N 144_L 1.795 0.99
39_P 42_V 1.76 0.99
77_Q 154_F 1.723 0.99
211_L 216_I 1.697 0.99
129_M 229_M 1.695 0.99
26_L 84_L 1.679 0.99
111_A 214_F 1.652 0.99
23_V 50_I 1.576 0.98
205_N 213_I 1.54 0.98
75_V 79_L 1.523 0.98
106_M 222_L 1.493 0.97
103_G 198_N 1.468 0.97
193_L 197_L 1.459 0.97
24_L 28_S 1.453 0.97
31_P 189_P 1.432 0.96
128_I 204_L 1.429 0.96
104_L 127_R 1.417 0.96
173_T 176_G 1.408 0.96
246_E 249_N 1.402 0.96
114_V 119_H 1.395 0.96
108_L 222_L 1.394 0.96
111_A 150_L 1.391 0.96
18_W 77_Q 1.376 0.95
25_A 28_S 1.359 0.95
54_I 151_V 1.355 0.95
208_A 215_V 1.352 0.95
18_W 73_L 1.336 0.94
92_F 133_A 1.328 0.94
197_L 224_V 1.295 0.93
49_M 52_F 1.288 0.92
16_Y 147_I 1.279 0.92
27_I 43_K 1.278 0.92
106_M 135_L 1.253 0.91
88_M 149_L 1.243 0.91
148_S 152_D 1.236 0.90
84_L 251_L 1.228 0.90
20_L 47_A 1.226 0.90
219_P 222_L 1.224 0.90
13_L 16_Y 1.22 0.90
179_I 183_G 1.219 0.90
103_G 108_L 1.209 0.89
106_M 194_L 1.205 0.89
193_L 207_M 1.187 0.88
21_L 78_I 1.18 0.87
212_S 218_F 1.179 0.87
53_A 57_S 1.173 0.87
205_N 212_S 1.167 0.87
20_L 48_M 1.165 0.86
186_L 220_L 1.155 0.86
159_I 198_N 1.147 0.85
121_N 235_L 1.147 0.85
27_I 56_P 1.141 0.85
58_L 184_L 1.139 0.85
154_F 218_F 1.137 0.85
73_L 76_Q 1.135 0.84
88_M 186_L 1.132 0.84
64_P 67_S 1.13 0.84
53_A 156_T 1.124 0.84
183_G 236_I 1.122 0.84
117_A 200_A 1.119 0.83
42_V 46_L 1.114 0.83
77_Q 80_I 1.112 0.83
49_M 87_T 1.11 0.83
141_N 148_S 1.109 0.83
29_T 82_I 1.104 0.82
23_V 198_N 1.103 0.82
100_E 137_F 1.092 0.81
212_S 215_V 1.089 0.81
109_S 123_P 1.085 0.81
126_A 183_G 1.078 0.80
205_N 218_F 1.072 0.80
19_P 77_Q 1.068 0.79
194_L 208_A 1.061 0.79
114_V 123_P 1.056 0.78
63_V 160_G 1.055 0.78
115_D 123_P 1.05 0.78
89_Q 198_N 1.049 0.77
195_L 206_R 1.045 0.77
135_L 225_G 1.042 0.77
131_M 135_L 1.04 0.77
67_S 70_A 1.039 0.77
133_A 194_L 1.039 0.77
110_F 212_S 1.034 0.76
48_M 55_A 1.033 0.76
220_L 231_A 1.033 0.76
25_A 85_G 1.027 0.75
151_V 155_H 1.027 0.75
89_Q 115_D 1.026 0.75
27_I 48_M 1.024 0.75
96_R 124_V 1.019 0.75
14_N 51_T 1.017 0.74
24_L 113_F 1.015 0.74
201_L 206_R 1.013 0.74
46_L 187_A 1.012 0.74
94_A 224_V 1.012 0.74
108_L 198_N 1.011 0.74
26_L 91_A 1.01 0.74
105_Q 188_L 1.009 0.73
183_G 187_A 1.007 0.73
71_L 75_V 1.007 0.73
208_A 211_L 1.005 0.73
20_L 45_G 1.004 0.73
66_F 156_T 1.004 0.73
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2zy9A20.54021.20.973Contact Map0.282
2m0sA10.10730.90.975Contact Map0.61
4httA20.54020.70.977Contact Map0.218
1wwiA10.19160.60.978Contact Map0.368
2ketA10.07660.50.979Contact Map1
3ghfA10.19160.50.979Contact Map0.327
1suyC20.0460.50.98Contact Map
2rbgA20.16090.40.981Contact Map0.538
1jb0J10.05360.40.981Contact Map
2nvjA10.09580.40.982Contact Map0.011
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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