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OPENSEQ.org

YEEE - UPF0394 inner membrane protein YeeE
UniProt: P33015 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11895
Length: 352 (343)
Sequences: 525
Seq/Len: 1.53

YEEE
Paralog alert: 0.10 [within 20: 0.02] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
78_V 324_F 2.745 1.00
115_T 286_G 2.678 1.00
55_G 212_L 2.428 1.00
119_M 290_V 2.391 1.00
22_G 203_T 2.296 0.99
48_A 308_L 2.147 0.99
18_V 206_L 2.127 0.99
263_F 267_K 1.859 0.97
51_V 208_G 1.806 0.96
13_A 264_I 1.756 0.95
92_G 101_R 1.731 0.94
118_V 206_L 1.717 0.94
93_G 98_T 1.716 0.94
10_I 14_L 1.654 0.92
49_I 322_L 1.651 0.92
48_A 204_A 1.62 0.91
23_R 271_E 1.617 0.91
89_V 93_G 1.59 0.90
340_P 344_A 1.58 0.90
115_T 289_G 1.552 0.89
30_F 326_I 1.544 0.89
9_L 257_G 1.543 0.89
24_F 98_T 1.509 0.87
20_Q 104_E 1.484 0.86
23_R 32_D 1.482 0.86
111_I 282_T 1.479 0.86
54_V 159_V 1.469 0.85
82_Y 331_T 1.466 0.85
341_Q 344_A 1.456 0.84
264_I 272_F 1.449 0.84
267_K 272_F 1.403 0.81
87_G 288_G 1.403 0.81
207_I 315_T 1.396 0.81
164_T 168_V 1.387 0.80
11_C 210_I 1.385 0.80
294_F 315_T 1.38 0.80
53_S 158_A 1.375 0.79
25_C 32_D 1.367 0.79
218_S 250_W 1.355 0.78
33_M 39_N 1.355 0.78
49_I 59_L 1.353 0.78
20_Q 25_C 1.333 0.76
50_S 164_T 1.325 0.76
252_V 256_L 1.306 0.74
83_I 298_I 1.305 0.74
211_A 289_G 1.304 0.74
110_W 304_I 1.285 0.72
184_P 188_G 1.264 0.71
19_M 289_G 1.261 0.70
18_V 210_I 1.252 0.70
72_F 320_I 1.238 0.68
35_I 333_S 1.237 0.68
115_T 119_M 1.237 0.68
27_T 306_N 1.232 0.68
26_L 29_G 1.223 0.67
81_G 324_F 1.221 0.67
148_T 165_L 1.219 0.67
91_A 112_A 1.218 0.67
54_V 155_P 1.217 0.67
26_L 96_T 1.216 0.66
75_L 81_G 1.215 0.66
47_I 316_W 1.21 0.66
230_T 296_A 1.207 0.66
178_K 181_T 1.205 0.65
274_V 283_L 1.202 0.65
97_G 101_R 1.198 0.65
162_V 166_W 1.191 0.64
55_G 208_G 1.185 0.63
67_Y 153_V 1.18 0.63
18_V 22_G 1.17 0.62
156_L 167_V 1.168 0.62
288_G 295_G 1.165 0.62
11_C 203_T 1.164 0.61
128_A 298_I 1.164 0.61
321_G 325_M 1.162 0.61
285_S 306_N 1.156 0.61
59_L 212_L 1.153 0.60
327_L 331_T 1.148 0.60
49_I 311_T 1.144 0.59
343_K 346_L 1.139 0.59
23_R 320_I 1.138 0.59
180_A 185_R 1.134 0.58
303_S 307_G 1.134 0.58
324_F 327_L 1.133 0.58
214_A 223_R 1.131 0.58
62_A 83_I 1.129 0.58
31_R 97_G 1.125 0.58
278_D 281_T 1.124 0.57
148_T 316_W 1.121 0.57
38_N 314_M 1.119 0.57
317_Q 321_G 1.116 0.57
88_I 302_C 1.113 0.56
97_G 293_G 1.112 0.56
176_K 287_L 1.112 0.56
204_A 238_Q 1.111 0.56
98_T 113_L 1.109 0.56
188_G 192_I 1.107 0.56
311_T 319_W 1.106 0.56
188_G 193_L 1.106 0.56
164_T 167_V 1.106 0.56
229_I 258_I 1.102 0.55
305_G 309_V 1.097 0.55
310_M 318_G 1.096 0.55
50_S 54_V 1.095 0.54
304_I 320_I 1.095 0.54
205_V 209_L 1.095 0.54
8_G 12_G 1.094 0.54
60_I 308_L 1.093 0.54
19_M 45_L 1.092 0.54
48_A 309_V 1.092 0.54
178_K 184_P 1.092 0.54
76_G 317_Q 1.084 0.53
293_G 304_I 1.08 0.53
14_L 308_L 1.079 0.53
12_G 92_G 1.077 0.53
339_R 342_R 1.076 0.52
202_V 206_L 1.076 0.52
31_R 89_V 1.074 0.52
102_A 113_L 1.072 0.52
54_V 166_W 1.071 0.52
208_G 313_M 1.069 0.52
12_G 16_G 1.069 0.52
14_L 213_L 1.069 0.52
209_L 290_V 1.068 0.52
146_A 149_F 1.066 0.51
29_G 45_L 1.065 0.51
113_L 231_S 1.064 0.51
11_C 213_L 1.064 0.51
72_F 75_L 1.061 0.51
10_I 298_I 1.061 0.51
118_V 204_A 1.058 0.51
82_Y 325_M 1.055 0.50
122_V 126_P 1.054 0.50
10_I 13_A 1.054 0.50
25_C 293_G 1.054 0.50
302_C 305_G 1.053 0.50
162_V 205_V 1.05 0.50
20_Q 265_A 1.05 0.50
101_R 106_L 1.049 0.50
177_L 185_R 1.048 0.50
116_Y 252_V 1.046 0.49
25_C 215_W 1.045 0.49
93_G 230_T 1.045 0.49
119_M 125_S 1.041 0.49
162_V 331_T 1.041 0.49
102_A 110_W 1.041 0.49
78_V 320_I 1.039 0.49
151_L 158_A 1.038 0.49
25_C 255_V 1.037 0.48
127_H 134_T 1.037 0.48
185_R 192_I 1.037 0.48
306_N 318_G 1.036 0.48
82_Y 205_V 1.034 0.48
130_G 134_T 1.033 0.48
126_P 321_G 1.033 0.48
118_V 344_A 1.03 0.48
108_G 218_S 1.027 0.47
341_Q 345_R 1.026 0.47
103_G 314_M 1.024 0.47
87_G 295_G 1.023 0.47
61_Q 204_A 1.021 0.47
63_G 90_L 1.021 0.47
20_Q 23_R 1.02 0.47
162_V 260_V 1.019 0.47
12_G 210_I 1.017 0.46
19_M 228_G 1.016 0.46
26_L 303_S 1.016 0.46
93_G 96_T 1.015 0.46
339_R 343_K 1.011 0.46
26_L 41_M 1.011 0.46
180_A 186_R 1.008 0.45
163_I 168_V 1.008 0.45
25_C 101_R 1.008 0.45
17_F 21_R 1.007 0.45
101_R 109_S 1.006 0.45
92_G 265_A 1.003 0.45
92_G 97_G 1 0.45
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
4apsA20.497215.50.965Contact Map0.172
2ks1B10.1258.70.969Contact Map0.019
2gfpA20.81826.10.971Contact Map0.104
2cfqA10.44895.70.971Contact Map0.304
2xutA30.49154.90.972Contact Map0.095
2kluA10.11084.90.972Contact Map0.353
1s7qA10.17334.30.973Contact Map
4ikvA10.49153.70.974Contact Map0.198
2jwaA20.10513.40.974Contact Map0.144
1pw4A10.4292.50.976Contact Map0.182

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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