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OPENSEQ.org

YEEA - Inner membrane protein YeeA
UniProt: P33011 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11891
Length: 352 (343)
Sequences: 374
Seq/Len: 1.09

YEEA
Paralog alert: 0.53 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
33_T 52_M 2.578 1.00
175_A 283_V 1.829 0.93
33_T 50_V 1.797 0.92
29_A 158_F 1.79 0.92
36_I 40_F 1.781 0.92
25_R 158_F 1.75 0.91
146_G 153_L 1.747 0.91
25_R 68_R 1.668 0.88
7_L 10_F 1.563 0.83
334_E 337_H 1.559 0.82
85_I 273_H 1.542 0.81
137_E 143_W 1.503 0.79
54_V 159_T 1.471 0.77
63_G 69_A 1.465 0.77
21_V 65_V 1.454 0.76
45_S 103_A 1.423 0.74
125_V 129_I 1.409 0.73
29_A 154_L 1.407 0.72
32_L 269_R 1.394 0.71
176_K 281_S 1.391 0.71
344_N 347_C 1.373 0.70
23_G 196_R 1.362 0.69
56_M 213_M 1.358 0.69
121_L 129_I 1.355 0.68
158_F 161_I 1.35 0.68
45_S 125_V 1.341 0.67
219_P 223_E 1.341 0.67
40_F 85_I 1.34 0.67
154_L 162_W 1.321 0.66
28_L 245_L 1.316 0.65
166_A 219_P 1.313 0.65
118_Y 126_T 1.311 0.65
25_R 147_D 1.308 0.64
302_N 306_E 1.308 0.64
317_D 343_S 1.303 0.64
29_A 162_W 1.302 0.64
17_H 21_V 1.28 0.62
27_A 153_L 1.274 0.61
36_I 187_S 1.273 0.61
29_A 161_I 1.272 0.61
17_H 20_I 1.267 0.61
155_A 166_A 1.265 0.61
330_W 338_Q 1.264 0.60
214_R 219_P 1.261 0.60
68_R 147_D 1.261 0.60
318_L 321_V 1.261 0.60
68_R 148_V 1.26 0.60
63_G 143_W 1.251 0.59
328_Y 332_N 1.241 0.58
120_G 161_I 1.237 0.58
6_S 10_F 1.237 0.58
215_G 223_E 1.234 0.58
89_L 150_L 1.229 0.57
340_E 344_N 1.229 0.57
337_H 344_N 1.228 0.57
83_G 213_M 1.217 0.56
24_T 74_G 1.215 0.56
220_A 223_E 1.212 0.56
329_V 333_M 1.208 0.55
85_I 91_L 1.206 0.55
317_D 347_C 1.203 0.55
310_Q 313_N 1.196 0.54
329_V 332_N 1.194 0.54
102_A 248_Q 1.193 0.54
123_I 129_I 1.191 0.54
213_M 223_E 1.186 0.53
27_A 149_I 1.182 0.53
327_G 330_W 1.182 0.53
54_V 122_L 1.181 0.53
49_L 147_D 1.178 0.52
156_M 175_A 1.176 0.52
333_M 336_A 1.172 0.52
53_V 56_M 1.169 0.52
179_T 276_Q 1.168 0.52
341_L 347_C 1.165 0.51
25_R 90_E 1.161 0.51
154_L 235_Q 1.16 0.51
28_L 74_G 1.157 0.50
82_L 146_G 1.157 0.50
78_L 266_Q 1.153 0.50
329_V 337_H 1.152 0.50
113_L 123_I 1.138 0.49
337_H 343_S 1.138 0.49
98_L 153_L 1.138 0.49
317_D 341_L 1.136 0.48
190_S 194_L 1.134 0.48
57_G 64_N 1.132 0.48
326_Y 342_L 1.13 0.48
115_K 158_F 1.129 0.48
22_H 248_Q 1.126 0.48
87_L 102_A 1.126 0.48
131_V 216_L 1.12 0.47
7_L 13_R 1.114 0.46
336_A 340_E 1.111 0.46
67_P 159_T 1.106 0.46
338_Q 345_L 1.105 0.46
26_V 115_K 1.104 0.45
324_P 341_L 1.102 0.45
312_L 315_H 1.101 0.45
6_S 324_P 1.101 0.45
296_A 309_R 1.097 0.45
62_W 166_A 1.095 0.45
292_Q 314_N 1.095 0.45
154_L 203_L 1.094 0.45
33_T 240_N 1.093 0.44
127_L 170_W 1.091 0.44
302_N 316_H 1.09 0.44
321_V 333_M 1.087 0.44
55_I 97_M 1.087 0.44
330_W 334_E 1.086 0.44
7_L 344_N 1.085 0.44
328_Y 334_E 1.085 0.44
120_G 138_I 1.083 0.43
307_E 310_Q 1.079 0.43
46_T 165_R 1.078 0.43
149_I 153_L 1.076 0.43
330_W 333_M 1.075 0.43
54_V 234_I 1.075 0.43
56_M 87_L 1.074 0.43
120_G 221_S 1.073 0.43
340_E 347_C 1.073 0.43
317_D 320_V 1.072 0.42
129_I 276_Q 1.07 0.42
326_Y 337_H 1.066 0.42
101_C 187_S 1.065 0.42
332_N 335_T 1.065 0.42
65_V 165_R 1.063 0.42
295_F 298_T 1.063 0.42
85_I 159_T 1.063 0.42
326_Y 341_L 1.062 0.42
31_L 248_Q 1.062 0.42
255_T 258_S 1.06 0.41
28_L 35_L 1.06 0.41
80_S 143_W 1.057 0.41
320_V 341_L 1.055 0.41
6_S 9_P 1.055 0.41
304_A 332_N 1.055 0.41
298_T 302_N 1.053 0.41
73_I 149_I 1.045 0.40
30_F 49_L 1.044 0.40
156_M 283_V 1.044 0.40
25_R 62_W 1.042 0.40
50_V 151_G 1.042 0.40
321_V 335_T 1.042 0.40
326_Y 338_Q 1.042 0.40
326_Y 333_M 1.04 0.40
36_I 78_L 1.038 0.39
78_L 150_L 1.034 0.39
151_G 171_R 1.032 0.39
17_H 148_V 1.031 0.39
112_A 285_A 1.029 0.39
343_S 347_C 1.026 0.38
173_Q 238_N 1.024 0.38
54_V 137_E 1.024 0.38
179_T 277_Q 1.023 0.38
55_I 224_T 1.02 0.38
126_T 129_I 1.019 0.38
321_V 344_N 1.019 0.38
25_R 152_S 1.019 0.38
330_W 345_L 1.018 0.38
323_T 329_V 1.018 0.38
340_E 343_S 1.016 0.37
336_A 342_L 1.015 0.37
41_T 56_M 1.012 0.37
299_E 305_V 1.012 0.37
329_V 334_E 1.012 0.37
344_N 348_R 1.012 0.37
73_I 219_P 1.01 0.37
326_Y 330_W 1.009 0.37
343_S 346_I 1.007 0.37
15_Y 33_T 1.004 0.36
118_Y 155_A 1.004 0.36
36_I 281_S 1.003 0.36
191_P 241_L 1.002 0.36
150_L 190_S 1.001 0.36
102_A 244_M 1.001 0.36
99_V 263_L 1 0.36
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
4eneA20.477344.20.953Contact Map0.095
2oltA30.531213.60.964Contact Map0.339
4jkvA20.39778.70.967Contact Map0.272
4k0jA60.53985.20.97Contact Map0.231
3ne5A10.474450.97Contact Map0.127
2c5kT10.25574.80.97Contact Map0.338
4huqS10.44034.60.971Contact Map0.027
2dnxA10.27274.10.971Contact Map0.312
1tqgA10.28693.80.972Contact Map0.221
3nd0A20.50573.70.972Contact Map0.138

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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