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OPENSEQ.org
YIHG - Probable acyltransferase YihG
UniProt: P32129 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11833
Length: 310 (298)
Sequences: 603
Seq/Len: 2.02
YIHG
Paralog alert: 0.16 [within 20: 0.03] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
237_C 299_L 3.283 1.00
233_N 262_D 3.174 1.00
156_Y 163_R 2.951 1.00
156_Y 160_H 2.908 1.00
156_Y 162_E 2.49 1.00
189_V 288_L 2.127 0.99
10_M 14_L 1.989 0.99
166_K 169_E 1.977 0.99
86_H 260_H 1.949 0.99
273_D 276_N 1.93 0.99
128_K 131_L 1.828 0.98
127_L 131_L 1.82 0.98
299_L 303_M 1.762 0.97
207_Q 300_T 1.748 0.97
128_K 151_R 1.741 0.97
157_L 160_H 1.7 0.96
196_Q 200_Q 1.688 0.96
154_R 158_L 1.649 0.95
262_D 294_E 1.616 0.95
84_E 260_H 1.607 0.94
202_T 211_P 1.596 0.94
82_Q 256_R 1.586 0.94
208_N 300_T 1.556 0.93
131_L 151_R 1.532 0.92
127_L 148_F 1.497 0.91
153_S 156_Y 1.491 0.91
160_H 163_R 1.481 0.91
127_L 134_V 1.44 0.89
129_Q 150_K 1.427 0.88
151_R 167_D 1.426 0.88
230_K 263_L 1.426 0.88
163_R 166_K 1.398 0.87
248_D 253_K 1.395 0.87
279_S 300_T 1.386 0.86
146_M 186_V 1.385 0.86
135_P 192_S 1.356 0.85
112_L 188_F 1.338 0.83
168_V 215_A 1.327 0.83
116_F 121_P 1.323 0.83
260_H 298_L 1.313 0.82
247_F 251_S 1.304 0.81
113_C 141_C 1.302 0.81
43_V 52_I 1.3 0.81
84_E 258_V 1.298 0.81
278_K 282_R 1.293 0.80
105_S 193_R 1.281 0.80
84_E 302_L 1.281 0.80
10_M 13_I 1.277 0.79
301_S 304_S 1.262 0.78
165_G 171_T 1.262 0.78
113_C 146_M 1.26 0.78
13_I 17_I 1.259 0.78
196_Q 199_H 1.254 0.78
301_S 305_S 1.254 0.78
297_R 301_S 1.253 0.78
128_K 135_P 1.253 0.78
65_Y 118_K 1.242 0.77
208_N 303_M 1.234 0.76
27_I 31_I 1.223 0.75
47_L 286_Q 1.22 0.75
29_V 71_L 1.217 0.75
183_T 228_F 1.209 0.74
151_R 216_G 1.209 0.74
129_Q 132_A 1.205 0.74
141_C 186_V 1.205 0.74
98_L 225_G 1.204 0.73
109_I 125_Y 1.202 0.73
247_F 257_I 1.202 0.73
166_K 170_T 1.197 0.73
13_I 16_A 1.195 0.73
126_F 171_T 1.19 0.72
152_Y 157_L 1.166 0.70
238_Y 295_K 1.157 0.69
121_P 145_D 1.156 0.69
209_L 292_W 1.153 0.69
193_R 198_K 1.151 0.69
82_Q 253_K 1.142 0.68
240_D 244_Q 1.139 0.67
96_W 183_T 1.132 0.67
293_Q 297_R 1.129 0.66
84_E 256_R 1.124 0.66
268_D 297_R 1.122 0.66
111_V 259_V 1.12 0.66
128_K 216_G 1.12 0.66
125_Y 292_W 1.112 0.65
134_V 279_S 1.11 0.64
220_A 237_C 1.109 0.64
19_L 247_F 1.107 0.64
30_T 36_P 1.106 0.64
14_L 18_T 1.102 0.64
151_R 192_S 1.098 0.63
168_V 272_G 1.098 0.63
68_C 146_M 1.091 0.63
233_N 295_K 1.086 0.62
145_D 273_D 1.078 0.61
11_T 158_L 1.078 0.61
50_P 54_R 1.075 0.61
33_C 36_P 1.072 0.60
181_H 185_I 1.067 0.60
171_T 175_C 1.067 0.60
158_L 282_R 1.066 0.60
125_Y 186_V 1.06 0.59
201_Q 216_G 1.058 0.59
123_N 184_T 1.056 0.59
112_L 127_L 1.055 0.59
106_W 193_R 1.055 0.59
146_M 167_D 1.054 0.59
264_Q 294_E 1.044 0.57
149_M 239_P 1.044 0.57
67_W 106_W 1.04 0.57
135_P 151_R 1.04 0.57
206_F 289_N 1.038 0.57
100_I 217_I 1.037 0.57
104_R 217_I 1.036 0.57
31_I 64_M 1.035 0.56
149_M 219_M 1.035 0.56
125_Y 148_F 1.034 0.56
127_L 234_V 1.033 0.56
290_S 294_E 1.032 0.56
42_I 184_T 1.031 0.56
220_A 275_I 1.028 0.56
68_C 113_C 1.027 0.56
120_I 185_I 1.027 0.56
100_I 288_L 1.025 0.55
276_N 282_R 1.023 0.55
112_L 277_D 1.023 0.55
155_A 158_L 1.022 0.55
141_C 148_F 1.021 0.55
153_S 259_V 1.02 0.55
131_L 135_P 1.017 0.54
184_T 245_P 1.017 0.54
100_I 189_V 1.015 0.54
67_W 71_L 1.014 0.54
198_K 252_G 1.009 0.54
156_Y 303_M 1.007 0.53
276_N 280_F 1.006 0.53
167_D 216_G 1.005 0.53
165_G 169_E 1.001 0.53
125_Y 141_C 1.001 0.53
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1iuqA10.893599.80.754Contact Map0.278
3bqhA10.31618.70.97Contact Map0.17
2kq9A10.13555.30.973Contact Map0.076
1ck7A10.40322.80.976Contact Map0.115
1fvgA10.45482.70.977Contact Map0.059
1ff3A30.45482.60.977Contact Map0.054
3k1rB10.09352.50.977Contact Map0.532
3e0mA40.32582.50.977Contact Map0.112
1z0pA10.11942.30.978Contact Map0.241
3pimA30.37120.978Contact Map0.159
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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