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DJLA - DnaJ-like protein DjlA
UniProt: P31680 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11570
Length: 271 (268)
Sequences: 408
Seq/Len: 1.52

DJLA
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
217_D 220_T 4.275 1.00
6_K 31_H 2.456 1.00
218_A 268_K 2.362 1.00
216_D 221_I 2.355 1.00
216_D 220_T 2.151 0.99
143_D 150_E 2.125 0.99
30_G 34_D 2.045 0.98
132_F 136_Q 1.957 0.98
69_K 76_D 1.919 0.97
61_V 136_Q 1.841 0.96
212_V 221_I 1.84 0.96
10_V 13_A 1.757 0.95
26_G 30_G 1.754 0.95
9_G 30_G 1.734 0.94
229_M 254_A 1.694 0.93
218_A 221_I 1.654 0.92
71_R 74_E 1.644 0.92
221_I 270_F 1.63 0.92
63_G 104_G 1.59 0.90
35_K 253_K 1.566 0.89
5_G 31_H 1.563 0.89
10_V 28_L 1.544 0.88
237_L 246_M 1.544 0.88
61_V 132_F 1.542 0.88
112_R 160_E 1.539 0.88
212_V 216_D 1.531 0.88
8_I 12_V 1.508 0.87
22_G 26_G 1.501 0.86
26_G 34_D 1.487 0.86
247_M 251_K 1.473 0.85
112_R 156_V 1.471 0.85
9_G 13_A 1.466 0.85
115_M 161_L 1.432 0.83
58_T 136_Q 1.427 0.82
22_G 30_G 1.427 0.82
13_A 22_G 1.426 0.82
102_R 105_K 1.41 0.81
204_E 214_P 1.407 0.81
92_A 95_T 1.39 0.80
81_S 94_R 1.387 0.80
220_T 244_P 1.385 0.80
81_S 91_G 1.377 0.79
239_A 247_M 1.36 0.78
7_I 215_T 1.347 0.77
25_L 171_F 1.34 0.77
191_G 201_P 1.322 0.75
125_R 232_H 1.321 0.75
14_L 17_G 1.31 0.74
6_K 34_D 1.31 0.74
9_G 242_L 1.294 0.73
78_H 195_Q 1.288 0.73
232_H 247_M 1.277 0.72
218_A 270_F 1.276 0.72
13_A 26_G 1.247 0.69
91_G 94_R 1.243 0.69
169_D 252_Q 1.228 0.67
257_I 267_Q 1.227 0.67
119_R 223_R 1.223 0.67
85_D 91_G 1.215 0.66
236_K 241_G 1.214 0.66
262_E 267_Q 1.2 0.65
65_L 153_V 1.196 0.64
64_H 153_V 1.196 0.64
207_C 268_K 1.184 0.63
59_F 63_G 1.183 0.63
13_A 30_G 1.177 0.63
133_L 223_R 1.17 0.62
30_G 268_K 1.164 0.61
83_L 231_E 1.158 0.61
236_K 251_K 1.152 0.60
93_S 96_A 1.151 0.60
163_I 270_F 1.149 0.60
7_I 11_A 1.146 0.59
251_K 255_Q 1.143 0.59
33_F 36_A 1.139 0.59
55_F 89_L 1.129 0.58
5_G 34_D 1.124 0.57
237_L 242_L 1.105 0.55
244_P 248_E 1.1 0.55
79_I 169_D 1.098 0.55
68_S 250_A 1.096 0.54
75_A 266_Q 1.094 0.54
161_L 222_K 1.092 0.54
105_K 242_L 1.089 0.54
122_C 230_S 1.087 0.53
97_A 241_G 1.083 0.53
187_Q 191_G 1.082 0.53
59_F 89_L 1.082 0.53
238_V 242_L 1.081 0.53
68_S 264_I 1.08 0.53
29_I 209_V 1.076 0.52
129_I 163_I 1.067 0.51
243_P 246_M 1.066 0.51
205_D 263_L 1.066 0.51
204_E 208_N 1.062 0.51
97_A 104_G 1.057 0.50
203_L 264_I 1.055 0.50
222_K 226_R 1.052 0.50
95_T 227_K 1.052 0.50
167_Q 228_L 1.048 0.49
205_D 211_G 1.046 0.49
61_V 211_G 1.042 0.49
14_L 23_V 1.042 0.49
59_F 109_Y 1.038 0.48
88_N 209_V 1.038 0.48
95_T 152_A 1.033 0.48
118_F 171_F 1.033 0.48
204_E 215_T 1.031 0.48
9_G 26_G 1.024 0.47
76_D 207_C 1.023 0.47
31_H 34_D 1.021 0.47
111_L 161_L 1.019 0.46
224_A 252_Q 1.019 0.46
19_G 100_A 1.018 0.46
17_G 87_M 1.015 0.46
134_E 239_A 1.013 0.46
142_A 147_H 1.011 0.46
106_S 266_Q 1.01 0.45
91_G 126_F 1.01 0.45
241_G 246_M 1.006 0.45
241_G 247_M 1.005 0.45
90_H 93_S 1 0.44
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2jxuA10.542499.80.77Contact Map0.067
2h5nA40.490899.80.777Contact Map0.436
2ou3A20.575699.80.786Contact Map0.343
3ag7A10.391199.80.789Contact Map0.228
3apqA20.228899.60.82Contact Map0.609
4j80A40.236299.60.823Contact Map0.612
2ys8A10.317399.60.824Contact Map0.568
2dmxA10.258399.50.826Contact Map0.479
2lgwA10.232599.50.826Contact Map0.408
1wjzA10.302699.50.826Contact Map0.519

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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