| UniProt: | P28638 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11498 | ||
| Length: | 294 (252) | ||
| Sequences: | 2153 | ||
| Seq/Len: | 8.54 |
| YHDJ
Paralog alert: 0.45 [within 20: 0.02] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 201_E | 231_V | 3.587 | 1.00 | |
| 223_A | 241_G | 3.282 | 1.00 | |
| 109_V | 127_Y | 3.02 | 1.00 | |
| 37_I | 72_C | 2.834 | 1.00 | |
| 35_D | 79_Q | 2.662 | 1.00 | |
| 84_I | 98_C | 2.656 | 1.00 | |
| 35_D | 77_K | 2.55 | 1.00 | |
| 205_K | 234_A | 2.485 | 1.00 | |
| 71_E | 74_R | 2.394 | 1.00 | |
| 226_F | 252_G | 2.356 | 1.00 | |
| 127_Y | 178_N | 2.347 | 1.00 | |
| 76_L | 80_G | 2.309 | 1.00 | |
| 223_A | 229_G | 2.293 | 1.00 | |
| 108_I | 180_W | 2.216 | 1.00 | |
| 37_I | 76_L | 2.212 | 1.00 | |
| 25_E | 242_I | 2.202 | 1.00 | |
| 213_N | 216_D | 2.198 | 1.00 | |
| 83_Y | 211_S | 2.162 | 1.00 | |
| 214_P | 236_G | 2.086 | 1.00 | |
| 18_I | 25_E | 2.026 | 1.00 | |
| 27_K | 71_E | 2.024 | 1.00 | |
| 32_E | 78_K | 2.002 | 1.00 | |
| 86_N | 94_I | 1.989 | 1.00 | |
| 229_G | 241_G | 1.952 | 1.00 | |
| 31_A | 74_R | 1.876 | 1.00 | |
| 254_R | 258_V | 1.869 | 1.00 | |
| 233_I | 239_F | 1.869 | 1.00 | |
| 99_R | 133_M | 1.837 | 1.00 | |
| 15_K | 238_K | 1.822 | 1.00 | |
| 20_G | 25_E | 1.821 | 1.00 | |
| 217_I | 238_K | 1.813 | 1.00 | |
| 212_S | 216_D | 1.809 | 1.00 | |
| 35_D | 216_D | 1.748 | 1.00 | |
| 43_Y | 128_E | 1.736 | 1.00 | |
| 201_E | 234_A | 1.731 | 1.00 | |
| 141_T | 213_N | 1.729 | 1.00 | |
| 34_V | 217_I | 1.71 | 1.00 | |
| 107_R | 129_P | 1.704 | 1.00 | |
| 19_H | 249_I | 1.702 | 1.00 | |
| 229_G | 239_F | 1.67 | 1.00 | |
| 110_W | 200_P | 1.663 | 1.00 | |
| 15_K | 239_F | 1.663 | 1.00 | |
| 201_E | 230_A | 1.636 | 1.00 | |
| 250_K | 253_L | 1.629 | 1.00 | |
| 43_Y | 85_M | 1.602 | 1.00 | |
| 40_D | 199_K | 1.579 | 1.00 | |
| 200_P | 203_L | 1.568 | 1.00 | |
| 104_I | 107_R | 1.536 | 1.00 | |
| 34_V | 240_I | 1.535 | 1.00 | |
| 38_F | 85_M | 1.517 | 1.00 | |
| 71_E | 75_V | 1.511 | 1.00 | |
| 30_P | 74_R | 1.504 | 1.00 | |
| 31_A | 71_E | 1.503 | 1.00 | |
| 111_S | 181_D | 1.501 | 1.00 | |
| 32_E | 77_K | 1.486 | 1.00 | |
| 65_L | 68_V | 1.45 | 0.99 | |
| 81_S | 132_M | 1.445 | 0.99 | |
| 112_Y | 128_E | 1.426 | 0.99 | |
| 26_L | 75_V | 1.412 | 0.99 | |
| 254_R | 257_D | 1.405 | 0.99 | |
| 223_A | 252_G | 1.394 | 0.99 | |
| 105_K | 134_V | 1.39 | 0.99 | |
| 59_D | 63_D | 1.384 | 0.99 | |
| 82_M | 98_C | 1.382 | 0.99 | |
| 108_I | 132_M | 1.374 | 0.99 | |
| 123_Y | 210_A | 1.368 | 0.99 | |
| 127_Y | 179_V | 1.364 | 0.99 | |
| 36_L | 212_S | 1.357 | 0.99 | |
| 205_K | 209_L | 1.356 | 0.99 | |
| 246_S | 250_K | 1.348 | 0.99 | |
| 72_C | 221_P | 1.343 | 0.99 | |
| 19_H | 246_S | 1.327 | 0.99 | |
| 226_F | 241_G | 1.322 | 0.99 | |
| 110_W | 130_I | 1.319 | 0.99 | |
| 241_G | 252_G | 1.297 | 0.98 | |
| 25_E | 28_K | 1.294 | 0.98 | |
| 78_K | 136_D | 1.283 | 0.98 | |
| 111_S | 126_M | 1.281 | 0.98 | |
| 17_I | 252_G | 1.28 | 0.98 | |
| 95_D | 99_R | 1.268 | 0.98 | |
| 243_E | 249_I | 1.264 | 0.98 | |
| 180_W | 207_I | 1.25 | 0.98 | |
| 212_S | 237_R | 1.245 | 0.98 | |
| 180_W | 206_R | 1.241 | 0.98 | |
| 230_A | 234_A | 1.229 | 0.98 | |
| 253_L | 257_D | 1.227 | 0.98 | |
| 73_H | 102_F | 1.209 | 0.97 | |
| 108_I | 207_I | 1.203 | 0.97 | |
| 217_I | 240_I | 1.191 | 0.97 | |
| 106_S | 123_Y | 1.164 | 0.96 | |
| 83_Y | 207_I | 1.163 | 0.96 | |
| 108_I | 206_R | 1.159 | 0.96 | |
| 195_H | 248_Y | 1.151 | 0.96 | |
| 93_F | 96_L | 1.146 | 0.96 | |
| 36_L | 208_I | 1.143 | 0.96 | |
| 130_I | 207_I | 1.134 | 0.96 | |
| 204_L | 207_I | 1.129 | 0.96 | |
| 40_D | 85_M | 1.127 | 0.95 | |
| 162_Y | 165_N | 1.122 | 0.95 | |
| 220_D | 228_T | 1.117 | 0.95 | |
| 20_G | 242_I | 1.115 | 0.95 | |
| 63_D | 67_E | 1.115 | 0.95 | |
| 95_D | 104_I | 1.114 | 0.95 | |
| 18_I | 242_I | 1.097 | 0.95 | |
| 202_A | 205_K | 1.096 | 0.94 | |
| 37_I | 80_G | 1.091 | 0.94 | |
| 66_F | 100_K | 1.078 | 0.94 | |
| 130_I | 203_L | 1.073 | 0.94 | |
| 30_P | 71_E | 1.06 | 0.93 | |
| 34_V | 75_V | 1.041 | 0.92 | |
| 85_M | 199_K | 1.037 | 0.92 | |
| 29_I | 75_V | 1.035 | 0.92 | |
| 78_K | 135_K | 1.03 | 0.92 | |
| 110_W | 203_L | 1.029 | 0.92 | |
| 223_A | 243_E | 1.018 | 0.91 | |
| 66_F | 70_A | 1.017 | 0.91 | |
| 84_I | 94_I | 1.009 | 0.91 | |
| 219_L | 242_I | 1.007 | 0.91 | |
| 182_F | 202_A | 1.001 | 0.90 | |
| 132_M | 211_S | 1 | 0.90 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1eg2A | 1 | 0.9252 | 100 | 0.395 | Contact Map | 0.728 |
| 1booA | 1 | 0.949 | 100 | 0.407 | Contact Map | 0.72 |
| 1g60A | 2 | 0.8367 | 100 | 0.439 | Contact Map | 0.799 |
| 2zigA | 2 | 0.8707 | 100 | 0.472 | Contact Map | 0.837 |
| 3v97A | 2 | 0.4184 | 97.7 | 0.9 | Contact Map | 0.567 |
| 2b78A | 1 | 0.4252 | 97.7 | 0.9 | Contact Map | 0.59 |
| 2b3tA | 1 | 0.4014 | 97.5 | 0.904 | Contact Map | 0.466 |
| 3vseA | 4 | 0.4626 | 97.5 | 0.904 | Contact Map | 0.568 |
| 2yxlA | 1 | 0.4558 | 97.4 | 0.906 | Contact Map | 0.591 |
| 3evzA | 1 | 0.4388 | 97.3 | 0.907 | Contact Map | 0.453 |
Sequence Conservation (Image Generated using WebLogo v3)