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RODZ - Cytoskeleton protein RodZ
UniProt: P27434 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10015
Length: 337 (329)
Sequences: 513
Seq/Len: 1.56
RODZ
Paralog alert: 0.00 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
261_A 303_A 2.812 1.00
47_I 72_V 2.724 1.00
39_L 64_Y 2.238 0.99
276_F 286_L 2.095 0.99
14_T 50_D 2.079 0.99
33_V 71_L 2.049 0.99
30_Q 44_V 2.023 0.98
259_F 280_Q 2.017 0.98
43_T 64_Y 1.987 0.98
260_T 305_Q 1.978 0.98
37_L 293_P 1.886 0.97
269_D 290_G 1.838 0.96
121_L 126_G 1.788 0.96
296_L 327_L 1.754 0.95
22_A 72_V 1.748 0.95
262_D 279_M 1.697 0.94
262_D 281_R 1.679 0.93
39_L 43_T 1.673 0.93
22_A 62_R 1.649 0.93
59_T 313_V 1.638 0.92
188_A 228_A 1.559 0.89
42_S 64_Y 1.535 0.89
33_V 68_Y 1.52 0.88
300_A 303_A 1.517 0.88
112_W 296_L 1.511 0.87
266_E 277_S 1.509 0.87
255_L 329_L 1.498 0.87
266_E 297_K 1.494 0.87
63_G 71_L 1.483 0.86
266_E 274_K 1.47 0.85
30_Q 41_V 1.453 0.85
290_G 293_P 1.426 0.83
20_R 24_E 1.42 0.83
40_K 43_T 1.418 0.83
38_C 64_Y 1.396 0.81
267_V 275_L 1.396 0.81
33_V 63_G 1.389 0.81
315_L 324_V 1.371 0.80
290_G 294_Y 1.364 0.79
44_V 71_L 1.362 0.79
47_I 69_A 1.361 0.79
7_H 10_N 1.344 0.78
50_D 61_L 1.342 0.77
269_D 288_L 1.341 0.77
6_T 11_E 1.339 0.77
258_N 285_N 1.333 0.77
126_G 133_W 1.333 0.77
259_F 304_V 1.328 0.76
269_D 293_P 1.327 0.76
27_G 262_D 1.316 0.76
26_L 73_H 1.31 0.75
181_P 194_P 1.309 0.75
38_C 67_S 1.297 0.74
131_W 301_P 1.293 0.74
29_S 32_A 1.283 0.73
37_L 71_L 1.268 0.72
57_A 64_Y 1.268 0.72
37_L 41_V 1.266 0.71
36_R 41_V 1.262 0.71
259_F 266_E 1.258 0.71
33_V 308_Y 1.256 0.71
34_A 64_Y 1.253 0.70
264_W 299_G 1.252 0.70
63_G 259_F 1.238 0.69
15_T 83_L 1.236 0.69
67_S 70_R 1.236 0.69
49_E 74_I 1.234 0.69
65_I 79_L 1.232 0.68
66_R 79_L 1.226 0.68
69_A 72_V 1.222 0.68
31_Q 44_V 1.22 0.67
69_A 79_L 1.219 0.67
207_Q 210_V 1.217 0.67
288_L 292_A 1.216 0.67
304_V 316_S 1.206 0.66
59_T 63_G 1.2 0.65
204_D 226_P 1.2 0.65
39_L 134_Q 1.196 0.65
37_L 324_V 1.189 0.64
297_K 324_V 1.189 0.64
204_D 228_A 1.185 0.64
122_F 255_L 1.183 0.64
71_L 308_Y 1.179 0.63
64_Y 301_P 1.177 0.63
183_S 247_T 1.167 0.62
38_C 43_T 1.167 0.62
40_K 60_F 1.165 0.62
196_V 203_V 1.151 0.61
298_I 302_A 1.146 0.60
294_Y 298_I 1.143 0.60
75_P 78_E 1.137 0.59
40_K 301_P 1.131 0.59
193_T 227_T 1.127 0.58
63_G 69_A 1.118 0.57
258_N 305_Q 1.118 0.57
39_L 325_A 1.117 0.57
301_P 317_R 1.115 0.57
51_K 54_A 1.113 0.57
44_V 266_E 1.111 0.57
169_S 186_T 1.11 0.57
50_D 67_S 1.107 0.56
46_D 55_D 1.103 0.56
60_F 293_P 1.1 0.56
36_R 66_R 1.086 0.54
60_F 64_Y 1.085 0.54
97_M 301_P 1.079 0.53
38_C 61_L 1.077 0.53
44_V 63_G 1.076 0.53
60_F 290_G 1.075 0.53
194_P 239_P 1.075 0.53
74_I 267_V 1.074 0.53
262_D 326_R 1.071 0.53
280_Q 286_L 1.062 0.52
172_T 205_P 1.061 0.51
67_S 324_V 1.061 0.51
4_E 11_E 1.06 0.51
33_V 273_K 1.06 0.51
59_T 327_L 1.059 0.51
38_C 71_L 1.053 0.51
66_R 70_R 1.05 0.50
46_D 56_L 1.05 0.50
15_T 259_F 1.047 0.50
63_G 68_Y 1.046 0.50
128_S 135_D 1.045 0.50
264_W 326_R 1.044 0.50
34_A 39_L 1.044 0.50
45_R 49_E 1.041 0.49
62_R 275_L 1.04 0.49
274_K 297_K 1.039 0.49
266_E 322_N 1.036 0.49
223_T 227_T 1.034 0.49
61_L 79_L 1.031 0.48
65_I 82_G 1.031 0.48
325_A 329_L 1.028 0.48
185_D 206_Q 1.026 0.48
313_V 327_L 1.023 0.48
322_N 330_N 1.022 0.47
185_D 199_P 1.021 0.47
2_N 7_H 1.021 0.47
259_F 267_V 1.02 0.47
117_T 120_V 1.019 0.47
213_P 216_A 1.018 0.47
297_K 304_V 1.016 0.47
278_G 314_D 1.014 0.47
268_T 274_K 1.012 0.46
68_Y 71_L 1.008 0.46
72_V 300_A 1.006 0.46
263_C 300_A 1.006 0.46
101_S 114_M 1.005 0.46
272_G 326_R 1.005 0.46
129_G 307_Q 1.002 0.45
66_R 69_A 1.002 0.45
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3fymA10.373999.70.747Contact Map0.452
4gqmA10.323499.20.817Contact Map0.248
2wusR20.317599.20.82Contact Map0.477
3f6wA50.240498.30.87Contact Map0.46
3kz3A20.234498.20.871Contact Map0.451
3g5gA140.252298.20.872Contact Map0.506
1y7yA20.219698.20.872Contact Map0.509
3eusA20.243398.20.873Contact Map0.45
2k9qA20.228598.10.874Contact Map0.304
2ef8A20.249398.10.874Contact Map0.275
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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