| UniProt: | P26647 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11377 | ||
| Length: | 245 (236) | ||
| Sequences: | 2270 | ||
| Seq/Len: | 9.62 |
| PLSC
Paralog alert: 0.21 [within 20: 0.01] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 178_C | 201_L | 4.504 | 1.00 | |
| 56_R | 197_I | 3.639 | 1.00 | |
| 60_D | 202_P | 3.617 | 1.00 | |
| 56_R | 199_E | 3.498 | 1.00 | |
| 96_K | 117_D | 3.405 | 1.00 | |
| 178_C | 225_M | 3.285 | 1.00 | |
| 54_E | 197_I | 3.144 | 1.00 | |
| 54_E | 195_L | 2.76 | 1.00 | |
| 222_R | 226_E | 2.752 | 1.00 | |
| 52_K | 195_L | 2.678 | 1.00 | |
| 201_L | 228_K | 2.548 | 1.00 | |
| 220_H | 224_I | 2.44 | 1.00 | |
| 57_K | 60_D | 2.439 | 1.00 | |
| 219_A | 223_S | 2.363 | 1.00 | |
| 99_L | 115_L | 2.274 | 1.00 | |
| 67_A | 175_I | 2.234 | 1.00 | |
| 228_K | 231_E | 2.22 | 1.00 | |
| 69_Y | 175_I | 2.109 | 1.00 | |
| 70_I | 163_A | 1.981 | 1.00 | |
| 199_E | 228_K | 1.971 | 1.00 | |
| 213_Q | 216_E | 1.953 | 1.00 | |
| 209_Y | 220_H | 1.95 | 1.00 | |
| 69_Y | 141_S | 1.899 | 1.00 | |
| 99_L | 109_W | 1.844 | 1.00 | |
| 65_G | 173_P | 1.843 | 1.00 | |
| 95_K | 118_R | 1.809 | 1.00 | |
| 177_V | 200_M | 1.782 | 1.00 | |
| 114_L | 142_I | 1.752 | 1.00 | |
| 97_S | 118_R | 1.742 | 1.00 | |
| 118_R | 149_T | 1.734 | 1.00 | |
| 178_C | 228_K | 1.692 | 1.00 | |
| 94_G | 98_L | 1.574 | 1.00 | |
| 96_K | 100_W | 1.557 | 1.00 | |
| 206_V | 209_Y | 1.552 | 1.00 | |
| 219_A | 222_R | 1.521 | 1.00 | |
| 72_N | 159_F | 1.496 | 1.00 | |
| 216_E | 220_H | 1.485 | 1.00 | |
| 70_I | 221_C | 1.464 | 1.00 | |
| 217_L | 221_C | 1.462 | 1.00 | |
| 156_L | 229_I | 1.441 | 1.00 | |
| 95_K | 149_T | 1.427 | 1.00 | |
| 226_E | 230_A | 1.409 | 0.99 | |
| 156_L | 226_E | 1.4 | 0.99 | |
| 180_S | 197_I | 1.389 | 0.99 | |
| 150_R | 154_R | 1.381 | 0.99 | |
| 178_C | 229_I | 1.381 | 0.99 | |
| 123_K | 126_G | 1.38 | 0.99 | |
| 82_A | 177_V | 1.36 | 0.99 | |
| 202_P | 224_I | 1.35 | 0.99 | |
| 173_P | 206_V | 1.327 | 0.99 | |
| 165_H | 169_A | 1.326 | 0.99 | |
| 159_F | 225_M | 1.317 | 0.99 | |
| 180_S | 199_E | 1.297 | 0.99 | |
| 223_S | 227_Q | 1.296 | 0.99 | |
| 85_I | 198_V | 1.293 | 0.99 | |
| 55_C | 200_M | 1.287 | 0.99 | |
| 74_Q | 150_R | 1.273 | 0.99 | |
| 164_F | 218_A | 1.264 | 0.99 | |
| 133_N | 137_K | 1.256 | 0.98 | |
| 134_H | 138_R | 1.244 | 0.98 | |
| 159_F | 222_R | 1.244 | 0.98 | |
| 71_A | 145_F | 1.219 | 0.98 | |
| 220_H | 223_S | 1.216 | 0.98 | |
| 173_P | 205_D | 1.207 | 0.98 | |
| 90_T | 143_W | 1.201 | 0.98 | |
| 201_L | 224_I | 1.196 | 0.98 | |
| 227_Q | 231_E | 1.193 | 0.98 | |
| 106_Q | 110_L | 1.186 | 0.98 | |
| 62_E | 175_I | 1.17 | 0.97 | |
| 120_N | 123_K | 1.15 | 0.97 | |
| 67_A | 173_P | 1.145 | 0.97 | |
| 151_S | 157_L | 1.138 | 0.97 | |
| 132_V | 136_K | 1.125 | 0.96 | |
| 106_Q | 109_W | 1.12 | 0.96 | |
| 201_L | 225_M | 1.111 | 0.96 | |
| 161_T | 165_H | 1.111 | 0.96 | |
| 70_I | 159_F | 1.109 | 0.96 | |
| 4_I | 8_I | 1.104 | 0.96 | |
| 7_L | 11_V | 1.101 | 0.96 | |
| 159_F | 226_E | 1.097 | 0.96 | |
| 61_A | 175_I | 1.089 | 0.95 | |
| 108_Y | 115_L | 1.078 | 0.95 | |
| 42_F | 102_P | 1.067 | 0.95 | |
| 205_D | 209_Y | 1.065 | 0.95 | |
| 13_Y | 17_V | 1.053 | 0.94 | |
| 116_I | 124_A | 1.05 | 0.94 | |
| 179_V | 182_T | 1.043 | 0.94 | |
| 53_V | 84_N | 1.043 | 0.94 | |
| 28_S | 31_N | 1.039 | 0.94 | |
| 150_R | 181_T | 1.027 | 0.93 | |
| 72_N | 156_L | 1.025 | 0.93 | |
| 234_K | 237_A | 1.025 | 0.93 | |
| 156_L | 222_R | 1.023 | 0.93 | |
| 204_I | 221_C | 1.023 | 0.93 | |
| 13_Y | 16_L | 1.015 | 0.93 | |
| 37_T | 41_M | 1.014 | 0.93 | |
| 69_Y | 86_V | 1.011 | 0.92 | |
| 92_T | 113_N | 1.006 | 0.92 | |
| 100_W | 109_W | 1.006 | 0.92 | |
| 97_S | 149_T | 1.004 | 0.92 | |
| 95_K | 150_R | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1iuqA | 1 | 0.9878 | 100 | 0.397 | Contact Map | 0.543 |
| 1r3eA | 1 | 0.4776 | 8.3 | 0.96 | Contact Map | 0.073 |
| 1sgvA | 2 | 0.4857 | 5.1 | 0.964 | Contact Map | 0.055 |
| 2xwsA | 1 | 0.4776 | 4.8 | 0.964 | Contact Map | 0.168 |
| 2fiqA | 4 | 0.551 | 4.7 | 0.964 | Contact Map | 0.136 |
| 3txvA | 1 | 0.5918 | 4.5 | 0.965 | Contact Map | 0.087 |
| 2ke4A | 1 | 0.1796 | 3 | 0.968 | Contact Map | 0.648 |
| 3f42A | 2 | 0.1592 | 2.8 | 0.968 | Contact Map | 0.433 |
| 4jpdA | 1 | 0.1633 | 2.5 | 0.969 | Contact Map | 0.356 |
| 1j3mA | 2 | 0.4327 | 2.3 | 0.97 | Contact Map | 0.396 |
Sequence Conservation (Image Generated using WebLogo v3)