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OPENSEQ.org
YGID - Uncharacterized protein YgiD
UniProt: P24197 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11166
Length: 262 (260)
Sequences: 889
Seq/Len: 3.42
YGID
Paralog alert: 0.06 [within 20: 0.01] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
91_R 156_E 6.426 1.00
73_Q 77_D 4.273 1.00
40_Q 157_G 2.558 1.00
38_R 126_D 2.387 1.00
7_P 154_R 2.359 1.00
43_V 92_L 2.351 1.00
5_R 155_D 2.348 1.00
145_E 148_R 2.317 1.00
203_E 206_P 2.295 1.00
85_S 130_V 2.292 1.00
41_A 158_I 2.225 1.00
42_I 127_I 2.189 1.00
65_I 109_G 2.164 1.00
43_V 132_L 2.072 1.00
22_D 27_R 2.014 1.00
54_T 135_D 2.013 1.00
187_S 215_G 1.976 1.00
226_Y 230_L 1.953 1.00
86_P 89_A 1.948 1.00
147_G 234_G 1.94 1.00
141_A 145_E 1.814 0.99
139_P 142_W 1.781 0.99
211_L 217_T 1.773 0.99
209_N 212_D 1.718 0.99
12_G 165_N 1.711 0.99
43_V 158_I 1.704 0.99
160_L 235_A 1.656 0.98
47_A 224_E 1.633 0.98
189_N 257_L 1.606 0.98
68_F 115_W 1.586 0.98
134_I 224_E 1.569 0.98
84_G 89_A 1.554 0.97
44_V 114_S 1.526 0.97
78_T 119_I 1.486 0.96
166_V 192_V 1.477 0.96
53_G 135_D 1.445 0.96
190_E 194_A 1.443 0.96
12_G 220_N 1.438 0.95
192_V 226_Y 1.438 0.95
162_A 232_V 1.422 0.95
45_V 231_Y 1.42 0.95
135_D 143_H 1.414 0.95
206_P 209_N 1.398 0.94
93_V 103_L 1.398 0.94
23_N 26_T 1.381 0.94
31_K 34_M 1.368 0.94
114_S 131_Q 1.345 0.93
64_T 82_A 1.332 0.92
75_L 115_W 1.324 0.92
144_F 204_Q 1.321 0.92
44_V 161_V 1.315 0.92
17_M 75_L 1.313 0.92
50_F 222_T 1.311 0.92
91_R 94_E 1.311 0.92
91_R 95_L 1.301 0.91
110_F 129_M 1.298 0.91
191_Y 213_H 1.292 0.91
118_L 129_M 1.285 0.90
83_P 86_P 1.273 0.90
10_F 14_G 1.269 0.90
172_T 218_L 1.258 0.89
147_G 235_A 1.245 0.89
74_A 77_D 1.221 0.87
95_L 153_L 1.218 0.87
165_N 256_M 1.217 0.87
96_L 149_K 1.21 0.87
68_F 75_L 1.207 0.86
63_P 108_W 1.205 0.86
144_F 148_R 1.182 0.85
50_F 224_E 1.182 0.85
54_T 132_L 1.181 0.85
58_A 103_L 1.18 0.85
64_T 68_F 1.177 0.84
57_T 131_Q 1.173 0.84
15_S 18_N 1.165 0.84
191_Y 214_E 1.157 0.83
66_H 79_H 1.152 0.83
110_F 114_S 1.151 0.83
191_Y 195_N 1.147 0.82
88_L 130_V 1.142 0.82
95_L 152_A 1.141 0.82
12_G 18_N 1.125 0.81
255_S 258_S 1.124 0.81
138_K 142_W 1.116 0.80
50_F 134_I 1.114 0.80
189_N 193_K 1.114 0.80
249_I 255_S 1.111 0.79
40_Q 156_E 1.097 0.78
194_A 198_W 1.096 0.78
38_R 127_I 1.094 0.78
8_A 232_V 1.09 0.78
88_L 92_L 1.085 0.77
49_W 131_Q 1.083 0.77
232_V 261_I 1.08 0.77
134_I 227_L 1.075 0.76
245_P 258_S 1.075 0.76
6_M 122_Y 1.059 0.75
70_G 76_Y 1.051 0.74
195_N 203_E 1.05 0.74
68_F 167_V 1.049 0.74
39_P 122_Y 1.048 0.74
21_E 74_A 1.043 0.73
167_V 219_S 1.041 0.73
43_V 160_L 1.035 0.72
117_V 167_V 1.026 0.71
45_V 132_L 1.023 0.71
172_T 184_W 1.021 0.71
244_I 259_V 1.019 0.71
44_V 118_L 1.017 0.70
115_W 167_V 1.016 0.70
140_A 223_P 1.014 0.70
17_M 20_L 1.01 0.70
249_I 257_L 1.01 0.70
25_Y 248_G 1.006 0.69
66_H 115_W 1.001 0.69
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2pw6A111000.231Contact Map0.717
1b4uB20.91981000.544Contact Map0.496
3vsjA20.96181000.562Contact Map0.502
3vsjB20.95421000.59Contact Map0.509
3bczA40.89311000.666Contact Map0.496
1fj2A20.671829.60.967Contact Map0.179
4f21A80.717625.70.967Contact Map0.179
3hxkA40.690824.60.968Contact Map0.234
3cn9A20.721421.10.969Contact Map0.141
2q7sA20.576319.50.969Contact Map0.441
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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