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OPENSEQ.org

YICC - UPF0701 protein YicC
UniProt: P23839 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11192
Length: 287 (287)
Sequences: 1027
Seq/Len: 3.58

YICC
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
164_T 229_Y 4.606 1.00
56_R 139_D 3.463 1.00
171_R 222_E 3.447 1.00
257_A 269_A 3.156 1.00
86_K 98_Q 2.774 1.00
183_E 187_A 2.759 1.00
52_R 135_D 2.669 1.00
82_E 94_W 2.636 1.00
3_R 146_E 2.587 1.00
22_W 66_L 2.339 1.00
81_N 117_A 2.291 1.00
173_H 262_N 2.288 1.00
49_V 134_L 2.284 1.00
57_L 62_V 2.279 1.00
1_M 4_S 2.204 1.00
159_R 275_L 2.191 1.00
153_K 157_E 2.173 1.00
179_Q 183_E 2.159 1.00
161_E 229_Y 2.15 1.00
26_S 141_F 2.108 1.00
253_S 276_I 2.107 1.00
163_V 272_L 2.029 1.00
144_A 227_E 2.003 1.00
36_F 49_V 1.997 1.00
170_V 265_V 1.945 1.00
155_L 219_D 1.944 1.00
57_L 141_F 1.87 1.00
146_E 150_Q 1.791 0.99
214_V 256_L 1.775 0.99
246_M 279_M 1.749 0.99
164_T 226_K 1.743 0.99
253_S 272_L 1.737 0.99
13_I 133_A 1.681 0.99
85_A 95_V 1.673 0.99
53_I 138_L 1.673 0.99
151_A 223_A 1.665 0.99
159_R 215_A 1.659 0.99
11_R 133_A 1.651 0.99
160_L 225_V 1.592 0.98
96_K 102_G 1.582 0.98
56_R 142_I 1.501 0.97
156_I 279_M 1.48 0.97
56_R 135_D 1.448 0.96
168_V 222_E 1.439 0.96
166_E 169_K 1.436 0.96
95_V 109_I 1.423 0.95
166_E 268_S 1.42 0.95
182_R 186_V 1.417 0.95
163_V 225_V 1.406 0.95
171_R 218_L 1.398 0.95
11_R 137_T 1.389 0.95
157_E 229_Y 1.387 0.95
177_I 265_V 1.387 0.95
105_N 108_D 1.358 0.94
35_Y 61_K 1.352 0.94
143_V 147_T 1.329 0.93
51_E 55_S 1.327 0.93
168_V 171_R 1.315 0.92
160_L 228_T 1.312 0.92
139_D 143_V 1.311 0.92
165_A 169_K 1.284 0.91
170_V 268_S 1.283 0.91
143_V 146_E 1.273 0.91
29_Q 61_K 1.266 0.90
157_E 161_E 1.266 0.90
155_L 159_R 1.261 0.90
30_R 277_E 1.254 0.90
275_L 278_Q 1.249 0.90
257_A 270_I 1.249 0.90
218_L 222_E 1.248 0.89
187_A 191_D 1.241 0.89
253_S 269_A 1.23 0.89
150_Q 153_K 1.229 0.88
186_V 198_N 1.215 0.88
22_W 133_A 1.206 0.87
20_A 133_A 1.193 0.86
250_N 258_S 1.188 0.86
136_G 139_D 1.186 0.86
147_T 230_N 1.183 0.86
140_D 143_V 1.182 0.86
173_H 264_E 1.179 0.86
189_L 201_L 1.168 0.85
263_A 267_N 1.164 0.85
168_V 172_S 1.162 0.84
228_T 249_F 1.16 0.84
53_I 64_C 1.16 0.84
34_T 53_I 1.16 0.84
164_T 168_V 1.156 0.84
221_L 249_F 1.154 0.84
176_E 179_Q 1.152 0.84
181_Q 212_I 1.142 0.83
86_K 99_S 1.136 0.83
169_K 268_S 1.132 0.82
32_L 62_V 1.127 0.82
131_L 135_D 1.126 0.82
200_R 204_E 1.12 0.81
161_E 165_A 1.118 0.81
42_F 68_Y 1.117 0.81
202_E 205_L 1.114 0.81
53_I 134_L 1.106 0.80
187_A 190_E 1.105 0.80
231_I 245_M 1.103 0.80
33_E 200_R 1.099 0.80
225_V 249_F 1.096 0.79
9_A 137_T 1.096 0.79
162_G 275_L 1.093 0.79
89_V 93_N 1.09 0.79
130_I 141_F 1.087 0.79
243_D 284_Q 1.085 0.78
236_E 240_R 1.083 0.78
19_S 69_E 1.076 0.78
83_K 168_V 1.072 0.77
214_V 265_V 1.067 0.77
161_E 164_T 1.066 0.77
200_R 203_Q 1.063 0.76
243_D 250_N 1.06 0.76
269_A 276_I 1.059 0.76
155_L 223_A 1.049 0.75
147_T 227_E 1.042 0.74
11_R 136_G 1.04 0.74
221_L 276_I 1.025 0.73
155_L 278_Q 1.024 0.72
43_R 61_K 1.02 0.72
90_T 93_N 1.019 0.72
163_V 249_F 1.018 0.72
109_I 115_V 1.016 0.72
24_M 53_I 1.015 0.72
29_Q 33_E 1.015 0.72
210_Q 274_V 1.014 0.71
186_V 190_E 1.014 0.71
48_V 127_A 1.012 0.71
210_Q 278_Q 1.008 0.71
219_D 278_Q 1.007 0.71
176_E 262_N 1.003 0.70
112_W 241_R 1.001 0.70
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2a01A30.522622.10.968Contact Map0.33
2qywA10.327521.30.968Contact Map0.492
2gqpA20.296218.20.969Contact Map0.059
2o8pA10.508715.80.97Contact Map0.199
3onjA10.327513.50.971Contact Map0.386
2werA20.275311.80.972Contact Map0.145
3zxqA20.146311.50.972Contact Map0
2ykoA30.432110.10.972Contact Map0.231
2lemA10.54018.70.973Contact Map0.111
2xcsB20.83628.60.973Contact Map0.177

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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