| UniProt: | P22186 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11084 | ||
| Length: | 152 (148) | ||
| Sequences: | 1132 | ||
| Seq/Len: | 7.65 |
| MRAZ
Paralog alert: 0.00 [within 20: 0.00] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 103_G | 124_T | 3.412 | 1.00 | |
| 107_E | 122_E | 3.304 | 1.00 | |
| 109_M | 122_E | 2.878 | 1.00 | |
| 52_E | 55_I | 2.721 | 1.00 | |
| 122_E | 126_H | 2.612 | 1.00 | |
| 36_C | 45_L | 2.573 | 1.00 | |
| 47_L | 117_F | 2.125 | 1.00 | |
| 14_G | 99_R | 2.001 | 1.00 | |
| 47_L | 119_L | 2 | 1.00 | |
| 7_L | 109_M | 1.953 | 1.00 | |
| 16_L | 110_L | 1.905 | 1.00 | |
| 105_T | 121_D | 1.803 | 1.00 | |
| 36_C | 94_I | 1.773 | 1.00 | |
| 124_T | 127_Q | 1.771 | 1.00 | |
| 9_N | 107_E | 1.76 | 1.00 | |
| 64_S | 70_E | 1.74 | 1.00 | |
| 3_R | 57_E | 1.712 | 1.00 | |
| 75_R | 118_E | 1.671 | 1.00 | |
| 82_S | 95_A | 1.67 | 1.00 | |
| 43_P | 124_T | 1.624 | 1.00 | |
| 137_Q | 140_T | 1.496 | 0.99 | |
| 2_F | 22_Y | 1.461 | 0.99 | |
| 127_Q | 130_K | 1.459 | 0.99 | |
| 10_L | 108_V | 1.439 | 0.99 | |
| 96_P | 99_R | 1.433 | 0.99 | |
| 52_E | 115_N | 1.423 | 0.99 | |
| 46_L | 116_K | 1.419 | 0.99 | |
| 35_V | 50_L | 1.412 | 0.99 | |
| 48_Y | 53_W | 1.412 | 0.99 | |
| 78_L | 114_F | 1.408 | 0.99 | |
| 22_Y | 110_L | 1.368 | 0.99 | |
| 79_G | 125_W | 1.338 | 0.98 | |
| 148_Q | 151_S | 1.327 | 0.98 | |
| 96_P | 100_Q | 1.265 | 0.98 | |
| 54_E | 58_Q | 1.254 | 0.97 | |
| 33_Q | 85_Q | 1.25 | 0.97 | |
| 60_L | 74_Q | 1.241 | 0.97 | |
| 36_C | 47_L | 1.236 | 0.97 | |
| 49_P | 52_E | 1.229 | 0.97 | |
| 22_Y | 117_F | 1.219 | 0.97 | |
| 104_L | 121_D | 1.204 | 0.97 | |
| 21_R | 83_E | 1.203 | 0.96 | |
| 123_T | 126_H | 1.192 | 0.96 | |
| 143_L | 149_D | 1.189 | 0.96 | |
| 48_Y | 56_I | 1.16 | 0.95 | |
| 42_H | 71_R | 1.153 | 0.95 | |
| 35_V | 44_C | 1.12 | 0.94 | |
| 78_L | 101_H | 1.111 | 0.94 | |
| 9_N | 106_K | 1.109 | 0.94 | |
| 16_L | 108_V | 1.108 | 0.94 | |
| 149_D | 152_L | 1.108 | 0.94 | |
| 53_W | 63_L | 1.106 | 0.94 | |
| 147_L | 151_S | 1.097 | 0.93 | |
| 68_P | 72_R | 1.095 | 0.93 | |
| 146_R | 149_D | 1.086 | 0.93 | |
| 2_F | 117_F | 1.085 | 0.93 | |
| 8_V | 110_L | 1.08 | 0.93 | |
| 121_D | 124_T | 1.077 | 0.92 | |
| 11_D | 15_R | 1.073 | 0.92 | |
| 145_E | 149_D | 1.071 | 0.92 | |
| 82_S | 97_V | 1.067 | 0.92 | |
| 53_W | 81_A | 1.064 | 0.92 | |
| 100_Q | 126_H | 1.053 | 0.91 | |
| 123_T | 127_Q | 1.048 | 0.91 | |
| 18_V | 110_L | 1.044 | 0.91 | |
| 74_Q | 116_K | 1.038 | 0.91 | |
| 127_Q | 131_E | 1.003 | 0.88 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1n0eA | 8 | 0.9276 | 100 | 0.039 | Contact Map | 0.913 |
| 2glwA | 1 | 0.5987 | 99.7 | 0.602 | Contact Map | 0.351 |
| 1yfbA | 2 | 0.3355 | 92.8 | 0.875 | Contact Map | 0.657 |
| 2l66A | 2 | 0.3355 | 89 | 0.886 | Contact Map | 0.388 |
| 2w1tA | 1 | 0.4868 | 86.7 | 0.89 | Contact Map | 0.576 |
| 1mvfD | 2 | 0.5197 | 62.3 | 0.911 | Contact Map | 0.666 |
| 3o27A | 2 | 0.3947 | 26.5 | 0.929 | Contact Map | 0.201 |
| 3d55A | 4 | 0.5329 | 15.4 | 0.936 | Contact Map | 0.811 |
| 3brcA | 2 | 0.3355 | 6 | 0.947 | Contact Map | 0.745 |
| 3hs2A | 8 | 0.3816 | 5.9 | 0.947 | Contact Map | 0.785 |
Sequence Conservation (Image Generated using WebLogo v3)