| UniProt: | P16681 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10712 | ||
| Length: | 147 (135) | ||
| Sequences: | 1640 | ||
| Seq/Len: | 12.15 |
| PHNB
Paralog alert: 0.44 [within 20: 0.05] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 17_I | 62_A | 2.98 | 1.00 | |
| 12_N | 15_D | 2.815 | 1.00 | |
| 14_S | 18_A | 2.759 | 1.00 | |
| 14_S | 33_S | 2.631 | 1.00 | |
| 101_R | 105_N | 2.58 | 1.00 | |
| 27_E | 65_R | 2.301 | 1.00 | |
| 18_A | 21_Q | 2.292 | 1.00 | |
| 111_K | 129_T | 2.197 | 1.00 | |
| 100_K | 104_D | 2.169 | 1.00 | |
| 95_Q | 98_E | 2.153 | 1.00 | |
| 116_W | 126_G | 1.957 | 1.00 | |
| 100_K | 124_G | 1.952 | 1.00 | |
| 6_Y | 74_S | 1.945 | 1.00 | |
| 29_L | 65_R | 1.904 | 1.00 | |
| 103_F | 126_G | 1.867 | 1.00 | |
| 21_Q | 28_L | 1.753 | 1.00 | |
| 116_W | 124_G | 1.66 | 1.00 | |
| 93_S | 99_G | 1.651 | 1.00 | |
| 99_G | 138_I | 1.648 | 1.00 | |
| 31_K | 59_I | 1.62 | 1.00 | |
| 64_V | 73_M | 1.609 | 1.00 | |
| 36_E | 56_D | 1.59 | 1.00 | |
| 6_Y | 90_V | 1.573 | 1.00 | |
| 63_N | 70_D | 1.511 | 1.00 | |
| 98_E | 101_R | 1.509 | 1.00 | |
| 109_N | 131_K | 1.497 | 1.00 | |
| 96_V | 100_K | 1.458 | 1.00 | |
| 126_G | 138_I | 1.452 | 1.00 | |
| 104_D | 107_A | 1.447 | 1.00 | |
| 8_S | 76_A | 1.443 | 1.00 | |
| 121_W | 125_F | 1.439 | 1.00 | |
| 17_I | 73_M | 1.419 | 1.00 | |
| 103_F | 112_I | 1.408 | 1.00 | |
| 16_A | 20_Y | 1.393 | 0.99 | |
| 102_W | 138_I | 1.377 | 0.99 | |
| 3_L | 71_I | 1.363 | 0.99 | |
| 17_I | 64_V | 1.349 | 0.99 | |
| 18_A | 22_R | 1.329 | 0.99 | |
| 96_V | 124_G | 1.327 | 0.99 | |
| 15_D | 18_A | 1.278 | 0.99 | |
| 10_A | 78_P | 1.259 | 0.99 | |
| 65_R | 70_D | 1.234 | 0.98 | |
| 121_W | 139_N | 1.225 | 0.98 | |
| 99_G | 116_W | 1.207 | 0.98 | |
| 8_S | 88_T | 1.205 | 0.98 | |
| 61_H | 72_M | 1.197 | 0.98 | |
| 113_E | 135_P | 1.163 | 0.97 | |
| 118_E | 122_A | 1.153 | 0.97 | |
| 14_S | 31_K | 1.141 | 0.97 | |
| 23_T | 105_N | 1.139 | 0.97 | |
| 20_Y | 132_F | 1.123 | 0.97 | |
| 64_V | 71_I | 1.109 | 0.96 | |
| 119_T | 122_A | 1.1 | 0.96 | |
| 67_A | 91_L | 1.097 | 0.96 | |
| 129_T | 135_P | 1.094 | 0.96 | |
| 24_L | 91_L | 1.079 | 0.95 | |
| 127_K | 137_M | 1.075 | 0.95 | |
| 24_L | 128_V | 1.045 | 0.94 | |
| 21_Q | 27_E | 1.023 | 0.93 | |
| 93_S | 102_W | 1.022 | 0.93 | |
| 96_V | 140_V | 1.022 | 0.93 | |
| 125_F | 137_M | 1.013 | 0.93 | |
| 60_A | 121_W | 1.003 | 0.93 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1u69A | 4 | 0.8299 | 100 | 0.354 | Contact Map | 0.773 |
| 1tsjA | 1 | 0.8844 | 99.9 | 0.473 | Contact Map | 0.735 |
| 1u6lA | 2 | 0.9456 | 99.8 | 0.495 | Contact Map | 0.767 |
| 1u7iA | 2 | 0.8707 | 99.8 | 0.53 | Contact Map | 0.778 |
| 3omsA | 1 | 0.8707 | 99.8 | 0.535 | Contact Map | 0.798 |
| 3l20A | 2 | 0.9524 | 99.8 | 0.538 | Contact Map | 0.635 |
| 1xy7A | 2 | 0.8844 | 99.5 | 0.614 | Contact Map | 0.699 |
| 2zw5A | 2 | 0.7823 | 99.5 | 0.615 | Contact Map | 0.665 |
| 3itwA | 2 | 0.8299 | 99.5 | 0.632 | Contact Map | 0.717 |
| 2rbbA | 2 | 0.8367 | 99.1 | 0.695 | Contact Map | 0.76 |
Sequence Conservation (Image Generated using WebLogo v3)