| UniProt: | P13016 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10041 | ||
| Length: | 183 (179) | ||
| Sequences: | 810 | ||
| Seq/Len: | 4.53 |
| AMPD
Paralog alert: 0.05 [within 20: 0.00] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 18_H | 54_G | 3.962 | 1.00 | |
| 31_L | 137_T | 3.451 | 1.00 | |
| 48_I | 77_L | 3.389 | 1.00 | |
| 127_D | 173_R | 3.093 | 1.00 | |
| 134_A | 177_L | 2.928 | 1.00 | |
| 137_T | 174_F | 2.915 | 1.00 | |
| 76_C | 90_F | 2.909 | 1.00 | |
| 117_L | 133_L | 2.686 | 1.00 | |
| 49_D | 87_Y | 2.68 | 1.00 | |
| 89_P | 92_K | 2.61 | 1.00 | |
| 19_Y | 92_K | 2.581 | 1.00 | |
| 76_C | 136_V | 2.549 | 1.00 | |
| 130_Y | 170_D | 2.461 | 1.00 | |
| 7_W | 13_R | 2.448 | 1.00 | |
| 84_I | 132_Q | 2.445 | 1.00 | |
| 20_D | 107_R | 2.443 | 1.00 | |
| 79_R | 85_V | 2.05 | 1.00 | |
| 12_R | 83_E | 2.014 | 1.00 | |
| 58_P | 67_I | 1.999 | 1.00 | |
| 21_C | 92_K | 1.855 | 1.00 | |
| 121_D | 163_T | 1.844 | 1.00 | |
| 20_D | 71_R | 1.84 | 1.00 | |
| 35_N | 121_D | 1.806 | 1.00 | |
| 88_V | 94_A | 1.799 | 1.00 | |
| 125_Y | 168_A | 1.766 | 1.00 | |
| 78_I | 133_L | 1.754 | 1.00 | |
| 79_R | 83_E | 1.733 | 0.99 | |
| 63_F | 66_E | 1.701 | 0.99 | |
| 46_P | 50_A | 1.695 | 0.99 | |
| 47_W | 50_A | 1.679 | 0.99 | |
| 93_R | 110_D | 1.675 | 0.99 | |
| 78_I | 117_L | 1.644 | 0.99 | |
| 19_Y | 89_P | 1.627 | 0.99 | |
| 46_P | 79_R | 1.597 | 0.99 | |
| 63_F | 67_I | 1.557 | 0.99 | |
| 33_V | 174_F | 1.546 | 0.99 | |
| 41_G | 120_T | 1.538 | 0.98 | |
| 31_L | 174_F | 1.531 | 0.98 | |
| 40_P | 63_F | 1.517 | 0.98 | |
| 47_W | 64_F | 1.515 | 0.98 | |
| 90_F | 140_L | 1.453 | 0.98 | |
| 100_S | 157_I | 1.445 | 0.97 | |
| 120_T | 123_L | 1.423 | 0.97 | |
| 58_P | 68_A | 1.37 | 0.96 | |
| 32_V | 157_I | 1.363 | 0.96 | |
| 103_Q | 150_N | 1.348 | 0.96 | |
| 12_R | 85_V | 1.327 | 0.95 | |
| 40_P | 67_I | 1.317 | 0.95 | |
| 50_A | 53_T | 1.315 | 0.95 | |
| 139_A | 143_C | 1.307 | 0.95 | |
| 54_G | 76_C | 1.286 | 0.94 | |
| 57_D | 60_A | 1.277 | 0.94 | |
| 127_D | 131_Q | 1.267 | 0.94 | |
| 65_A | 68_A | 1.265 | 0.93 | |
| 42_E | 61_H | 1.257 | 0.93 | |
| 14_V | 53_T | 1.239 | 0.92 | |
| 29_T | 150_N | 1.237 | 0.92 | |
| 90_F | 144_Y | 1.219 | 0.92 | |
| 32_V | 152_T | 1.213 | 0.91 | |
| 158_A | 161_R | 1.159 | 0.89 | |
| 102_Y | 150_N | 1.148 | 0.88 | |
| 18_H | 76_C | 1.143 | 0.88 | |
| 3_L | 8_L | 1.139 | 0.88 | |
| 101_Q | 104_G | 1.137 | 0.87 | |
| 20_D | 93_R | 1.137 | 0.87 | |
| 35_N | 166_G | 1.123 | 0.87 | |
| 8_L | 136_V | 1.104 | 0.85 | |
| 35_N | 125_Y | 1.063 | 0.82 | |
| 90_F | 136_V | 1.06 | 0.82 | |
| 172_A | 176_V | 1.043 | 0.81 | |
| 173_R | 177_L | 1.032 | 0.80 | |
| 50_A | 70_L | 1.014 | 0.78 | |
| 43_F | 123_L | 1.013 | 0.78 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1j3gA | 1 | 1 | 100 | 0.292 | Contact Map | 0.465 |
| 4bxjA | 2 | 0.8361 | 100 | 0.407 | Contact Map | 0.787 |
| 3d2yA | 1 | 0.8579 | 100 | 0.413 | Contact Map | 0.584 |
| 4bolA | 2 | 0.8634 | 100 | 0.423 | Contact Map | 0.789 |
| 3latA | 2 | 0.8743 | 100 | 0.477 | Contact Map | 0.473 |
| 3hmaA | 2 | 0.8361 | 100 | 0.517 | Contact Map | 0.603 |
| 1yb0A | 3 | 0.8361 | 100 | 0.524 | Contact Map | 0.615 |
| 1ohtA | 1 | 0.8852 | 100 | 0.537 | Contact Map | 0.435 |
| 2rkqA | 1 | 0.847 | 100 | 0.541 | Contact Map | 0.495 |
| 2cb3A | 4 | 0.8743 | 100 | 0.543 | Contact Map | 0.499 |
Sequence Conservation (Image Generated using WebLogo v3)