| UniProt: | P12295 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11058 | ||
| Length: | 229 (221) | ||
| Sequences: | 1517 | ||
| Seq/Len: | 6.86 |
| UNG
Paralog alert: 0.04 [within 20: 0.00] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 172_G | 184_K | 3.605 | 1.00 | |
| 152_I | 159_V | 3.293 | 1.00 | |
| 169_Q | 184_K | 3.211 | 1.00 | |
| 162_L | 206_A | 3.027 | 1.00 | |
| 99_T | 204_V | 2.984 | 1.00 | |
| 129_R | 132_Q | 2.935 | 1.00 | |
| 26_T | 139_L | 2.836 | 1.00 | |
| 38_Y | 69_P | 2.695 | 1.00 | |
| 211_E | 217_P | 2.653 | 1.00 | |
| 48_F | 148_V | 2.643 | 1.00 | |
| 124_T | 167_H | 2.568 | 1.00 | |
| 181_H | 209_W | 2.497 | 1.00 | |
| 40_P | 43_D | 2.364 | 1.00 | |
| 14_E | 19_Y | 2.345 | 1.00 | |
| 185_A | 200_C | 2.237 | 1.00 | |
| 166_S | 169_Q | 2.235 | 1.00 | |
| 35_V | 129_R | 2.222 | 1.00 | |
| 112_E | 116_R | 2.066 | 1.00 | |
| 166_S | 170_K | 2.039 | 1.00 | |
| 161_F | 180_H | 2.012 | 1.00 | |
| 50_F | 116_R | 1.941 | 1.00 | |
| 52_E | 55_D | 1.939 | 1.00 | |
| 99_T | 201_N | 1.936 | 1.00 | |
| 201_N | 204_V | 1.894 | 1.00 | |
| 81_P | 110_Y | 1.888 | 1.00 | |
| 73_H | 80_R | 1.878 | 1.00 | |
| 30_E | 129_R | 1.868 | 1.00 | |
| 95_E | 199_G | 1.824 | 1.00 | |
| 176_D | 179_R | 1.824 | 1.00 | |
| 158_G | 213_R | 1.791 | 1.00 | |
| 43_D | 80_R | 1.79 | 1.00 | |
| 209_W | 213_R | 1.788 | 1.00 | |
| 100_I | 103_F | 1.781 | 1.00 | |
| 160_V | 209_W | 1.774 | 1.00 | |
| 146_D | 171_K | 1.774 | 1.00 | |
| 14_E | 17_Q | 1.771 | 1.00 | |
| 147_K | 150_S | 1.753 | 1.00 | |
| 73_H | 78_S | 1.736 | 1.00 | |
| 183_L | 202_H | 1.682 | 1.00 | |
| 162_L | 202_H | 1.679 | 1.00 | |
| 68_G | 131_G | 1.671 | 1.00 | |
| 43_D | 46_N | 1.668 | 1.00 | |
| 98_N | 201_N | 1.661 | 1.00 | |
| 6_T | 54_G | 1.643 | 1.00 | |
| 23_T | 139_L | 1.635 | 1.00 | |
| 56_V | 152_I | 1.63 | 1.00 | |
| 97_E | 105_R | 1.58 | 1.00 | |
| 181_H | 213_R | 1.579 | 1.00 | |
| 85_I | 93_Y | 1.572 | 1.00 | |
| 134_H | 167_H | 1.541 | 0.99 | |
| 158_G | 209_W | 1.508 | 0.99 | |
| 153_N | 176_D | 1.508 | 0.99 | |
| 139_L | 142_E | 1.503 | 0.99 | |
| 73_H | 110_Y | 1.492 | 0.99 | |
| 52_E | 56_V | 1.49 | 0.99 | |
| 160_V | 206_A | 1.462 | 0.99 | |
| 31_R | 44_V | 1.457 | 0.99 | |
| 191_L | 195_R | 1.453 | 0.99 | |
| 57_K | 216_T | 1.449 | 0.99 | |
| 150_S | 174_I | 1.446 | 0.99 | |
| 208_Q | 212_Q | 1.41 | 0.99 | |
| 44_V | 127_T | 1.4 | 0.99 | |
| 36_T | 130_A | 1.394 | 0.99 | |
| 193_A | 198_F | 1.382 | 0.99 | |
| 108_H | 113_S | 1.37 | 0.98 | |
| 81_P | 108_H | 1.369 | 0.98 | |
| 103_F | 106_P | 1.361 | 0.98 | |
| 208_Q | 211_E | 1.357 | 0.98 | |
| 97_E | 104_T | 1.321 | 0.98 | |
| 53_L | 152_I | 1.316 | 0.98 | |
| 100_I | 204_V | 1.306 | 0.98 | |
| 67_H | 87_P | 1.293 | 0.97 | |
| 26_T | 30_E | 1.292 | 0.97 | |
| 92_M | 203_F | 1.291 | 0.97 | |
| 67_H | 71_Q | 1.289 | 0.97 | |
| 137_A | 167_H | 1.276 | 0.97 | |
| 29_S | 33_S | 1.254 | 0.97 | |
| 177_K | 184_K | 1.254 | 0.97 | |
| 30_E | 35_V | 1.253 | 0.97 | |
| 10_V | 151_L | 1.243 | 0.97 | |
| 150_S | 154_Q | 1.219 | 0.96 | |
| 38_Y | 68_G | 1.206 | 0.96 | |
| 183_L | 200_C | 1.199 | 0.96 | |
| 205_L | 208_Q | 1.196 | 0.95 | |
| 191_L | 194_H | 1.194 | 0.95 | |
| 129_R | 135_S | 1.193 | 0.95 | |
| 153_N | 174_I | 1.172 | 0.95 | |
| 125_V | 137_A | 1.17 | 0.95 | |
| 46_N | 50_F | 1.165 | 0.95 | |
| 177_K | 182_V | 1.143 | 0.94 | |
| 46_N | 73_H | 1.14 | 0.94 | |
| 128_V | 135_S | 1.134 | 0.94 | |
| 67_H | 133_A | 1.13 | 0.93 | |
| 147_K | 151_L | 1.128 | 0.93 | |
| 24_L | 27_V | 1.124 | 0.93 | |
| 113_S | 223_V | 1.12 | 0.93 | |
| 50_F | 112_E | 1.116 | 0.93 | |
| 53_L | 156_R | 1.111 | 0.93 | |
| 172_G | 182_V | 1.108 | 0.92 | |
| 125_V | 167_H | 1.106 | 0.92 | |
| 194_H | 198_F | 1.104 | 0.92 | |
| 27_V | 31_R | 1.098 | 0.92 | |
| 125_V | 134_H | 1.09 | 0.92 | |
| 71_Q | 87_P | 1.079 | 0.91 | |
| 113_S | 219_D | 1.053 | 0.90 | |
| 28_A | 41_Q | 1.053 | 0.90 | |
| 24_L | 28_A | 1.044 | 0.89 | |
| 59_V | 161_F | 1.032 | 0.88 | |
| 98_N | 198_F | 1.024 | 0.88 | |
| 87_P | 190_P | 1.023 | 0.88 | |
| 186_P | 196_G | 1.021 | 0.88 | |
| 125_V | 142_E | 1.02 | 0.88 | |
| 46_N | 49_R | 1.018 | 0.88 | |
| 96_L | 103_F | 1.004 | 0.87 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3uf7A | 1 | 1 | 100 | 0.034 | Contact Map | 0.79 |
| 3tr7A | 1 | 0.9869 | 100 | 0.052 | Contact Map | 0.752 |
| 3zoqA | 1 | 0.9738 | 100 | 0.061 | Contact Map | 0.795 |
| 3cxmA | 1 | 1 | 100 | 0.062 | Contact Map | 0.736 |
| 2booA | 1 | 0.9913 | 100 | 0.065 | Contact Map | 0.763 |
| 3fciA | 1 | 0.9694 | 100 | 0.07 | Contact Map | 0.72 |
| 3a7nA | 1 | 0.9563 | 100 | 0.073 | Contact Map | 0.691 |
| 2j8xA | 2 | 0.9607 | 100 | 0.074 | Contact Map | 0.647 |
| 1udgA | 1 | 0.9563 | 100 | 0.086 | Contact Map | 0.68 |
| 2owrA | 8 | 0.8996 | 100 | 0.181 | Contact Map | 0.568 |
Sequence Conservation (Image Generated using WebLogo v3)