| UniProt: | P10908 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11050 | ||
| Length: | 247 (237) | ||
| Sequences: | 3803 | ||
| Seq/Len: | 16.05 |
| UGPQ
Paralog alert: 0.70 [within 20: 0.03] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 204_K | 230_D | 3.327 | 1.00 | |
| 25_A | 92_E | 2.906 | 1.00 | |
| 216_N | 235_D | 2.849 | 1.00 | |
| 77_L | 99_Q | 2.721 | 1.00 | |
| 72_N | 75_D | 2.686 | 1.00 | |
| 27_I | 40_F | 2.673 | 1.00 | |
| 17_K | 236_A | 2.582 | 1.00 | |
| 29_V | 32_K | 2.545 | 1.00 | |
| 98_S | 135_E | 2.404 | 1.00 | |
| 73_W | 96_L | 2.396 | 1.00 | |
| 11_A | 26_S | 2.382 | 1.00 | |
| 53_L | 68_A | 2.333 | 1.00 | |
| 18_L | 238_D | 2.331 | 1.00 | |
| 73_W | 77_L | 2.258 | 1.00 | |
| 67_V | 70_E | 2.203 | 1.00 | |
| 58_L | 79_V | 2.192 | 1.00 | |
| 112_N | 146_S | 2.13 | 1.00 | |
| 28_D | 103_R | 2.114 | 1.00 | |
| 52_L | 100_V | 2.093 | 1.00 | |
| 62_S | 81_A | 2.043 | 1.00 | |
| 102_E | 136_L | 2 | 1.00 | |
| 46_K | 72_N | 1.999 | 1.00 | |
| 45_S | 51_F | 1.997 | 1.00 | |
| 28_D | 32_K | 1.99 | 1.00 | |
| 23_T | 81_A | 1.965 | 1.00 | |
| 98_S | 132_A | 1.954 | 1.00 | |
| 221_A | 240_I | 1.905 | 1.00 | |
| 49_E | 73_W | 1.888 | 1.00 | |
| 40_F | 52_L | 1.855 | 1.00 | |
| 24_L | 95_P | 1.806 | 1.00 | |
| 40_F | 100_V | 1.744 | 1.00 | |
| 53_L | 61_T | 1.735 | 1.00 | |
| 217_K | 220_R | 1.708 | 1.00 | |
| 96_L | 99_Q | 1.693 | 1.00 | |
| 10_V | 37_M | 1.69 | 1.00 | |
| 59_E | 66_G | 1.684 | 1.00 | |
| 97_L | 113_I | 1.658 | 1.00 | |
| 13_R | 21_E | 1.651 | 1.00 | |
| 145_L | 156_A | 1.649 | 1.00 | |
| 166_G | 187_S | 1.626 | 1.00 | |
| 29_V | 33_Y | 1.625 | 1.00 | |
| 31_A | 109_M | 1.624 | 1.00 | |
| 49_E | 96_L | 1.623 | 1.00 | |
| 16_G | 26_S | 1.55 | 1.00 | |
| 59_E | 65_W | 1.548 | 1.00 | |
| 76_L | 94_L | 1.535 | 1.00 | |
| 146_S | 189_H | 1.53 | 1.00 | |
| 51_F | 73_W | 1.515 | 1.00 | |
| 58_L | 71_L | 1.511 | 1.00 | |
| 15_G | 18_L | 1.49 | 1.00 | |
| 190_L | 212_V | 1.463 | 1.00 | |
| 64_G | 79_V | 1.445 | 1.00 | |
| 44_L | 128_M | 1.439 | 1.00 | |
| 236_A | 239_V | 1.439 | 1.00 | |
| 11_A | 15_G | 1.437 | 1.00 | |
| 211_L | 231_C | 1.424 | 1.00 | |
| 146_S | 233_C | 1.417 | 1.00 | |
| 98_S | 136_L | 1.416 | 1.00 | |
| 128_M | 131_L | 1.409 | 1.00 | |
| 157_Q | 165_R | 1.393 | 0.99 | |
| 203_L | 210_I | 1.389 | 0.99 | |
| 48_G | 128_M | 1.382 | 0.99 | |
| 66_G | 71_L | 1.372 | 0.99 | |
| 155_A | 159_A | 1.367 | 0.99 | |
| 127_K | 131_L | 1.357 | 0.99 | |
| 80_D | 91_G | 1.35 | 0.99 | |
| 132_A | 136_L | 1.349 | 0.99 | |
| 37_M | 110_M | 1.345 | 0.99 | |
| 62_S | 66_G | 1.336 | 0.99 | |
| 44_L | 50_I | 1.333 | 0.99 | |
| 19_A | 29_V | 1.316 | 0.99 | |
| 127_K | 159_A | 1.312 | 0.99 | |
| 197_K | 201_M | 1.309 | 0.99 | |
| 212_V | 229_V | 1.29 | 0.99 | |
| 133_A | 145_L | 1.284 | 0.99 | |
| 45_S | 76_L | 1.283 | 0.99 | |
| 27_I | 52_L | 1.266 | 0.99 | |
| 9_I | 240_I | 1.265 | 0.99 | |
| 155_A | 158_Q | 1.265 | 0.99 | |
| 15_G | 29_V | 1.265 | 0.99 | |
| 24_L | 103_R | 1.259 | 0.99 | |
| 71_L | 76_L | 1.244 | 0.98 | |
| 145_L | 163_L | 1.244 | 0.98 | |
| 131_L | 135_E | 1.223 | 0.98 | |
| 51_F | 68_A | 1.223 | 0.98 | |
| 200_V | 204_K | 1.219 | 0.98 | |
| 55_D | 60_R | 1.219 | 0.98 | |
| 215_V | 221_A | 1.205 | 0.98 | |
| 45_S | 73_W | 1.194 | 0.98 | |
| 200_V | 210_I | 1.192 | 0.98 | |
| 130_A | 156_A | 1.176 | 0.98 | |
| 115_I | 152_A | 1.172 | 0.98 | |
| 21_E | 60_R | 1.169 | 0.97 | |
| 213_Y | 233_C | 1.168 | 0.97 | |
| 134_R | 160_A | 1.168 | 0.97 | |
| 220_R | 223_E | 1.161 | 0.97 | |
| 126_G | 155_A | 1.159 | 0.97 | |
| 10_V | 112_N | 1.152 | 0.97 | |
| 45_S | 49_E | 1.146 | 0.97 | |
| 192_H | 220_R | 1.139 | 0.97 | |
| 24_L | 28_D | 1.138 | 0.97 | |
| 204_K | 210_I | 1.136 | 0.97 | |
| 39_E | 54_H | 1.135 | 0.97 | |
| 57_N | 67_V | 1.134 | 0.97 | |
| 223_E | 227_W | 1.134 | 0.97 | |
| 112_N | 233_C | 1.13 | 0.97 | |
| 50_I | 129_V | 1.12 | 0.96 | |
| 157_Q | 186_V | 1.119 | 0.96 | |
| 222_A | 226_R | 1.115 | 0.96 | |
| 42_A | 113_I | 1.114 | 0.96 | |
| 203_L | 208_L | 1.114 | 0.96 | |
| 49_E | 98_S | 1.114 | 0.96 | |
| 11_A | 16_G | 1.112 | 0.96 | |
| 112_N | 189_H | 1.111 | 0.96 | |
| 42_A | 97_L | 1.11 | 0.96 | |
| 27_I | 38_I | 1.105 | 0.96 | |
| 153_L | 165_R | 1.097 | 0.96 | |
| 126_G | 152_A | 1.086 | 0.96 | |
| 71_L | 75_D | 1.086 | 0.96 | |
| 75_D | 78_R | 1.076 | 0.95 | |
| 27_I | 100_V | 1.068 | 0.95 | |
| 98_S | 102_E | 1.066 | 0.95 | |
| 81_A | 95_P | 1.062 | 0.95 | |
| 101_A | 111_A | 1.061 | 0.95 | |
| 51_F | 76_L | 1.059 | 0.95 | |
| 189_H | 211_L | 1.044 | 0.94 | |
| 146_S | 166_G | 1.037 | 0.94 | |
| 53_L | 94_L | 1.035 | 0.94 | |
| 221_A | 232_I | 1.03 | 0.94 | |
| 22_N | 95_P | 1.028 | 0.94 | |
| 105_R | 140_M | 1.023 | 0.93 | |
| 156_A | 165_R | 1.02 | 0.93 | |
| 15_G | 33_Y | 1.018 | 0.93 | |
| 16_G | 235_D | 1.009 | 0.93 | |
| 42_A | 50_I | 1.007 | 0.93 | |
| 104_C | 111_A | 1 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 2otdA | 4 | 1 | 100 | 0.038 | Contact Map | 0.799 |
| 3qvqA | 4 | 0.9919 | 100 | 0.063 | Contact Map | 0.845 |
| 2pz0A | 2 | 0.9919 | 100 | 0.072 | Contact Map | 0.885 |
| 1zccA | 6 | 0.9393 | 100 | 0.114 | Contact Map | 0.796 |
| 3ch0A | 1 | 0.9717 | 100 | 0.119 | Contact Map | 0.797 |
| 3l12A | 2 | 0.9919 | 100 | 0.123 | Contact Map | 0.784 |
| 2o55A | 1 | 0.9636 | 100 | 0.123 | Contact Map | 0.703 |
| 3ks6A | 4 | 0.9555 | 100 | 0.123 | Contact Map | 0.721 |
| 2oogA | 6 | 0.9838 | 100 | 0.128 | Contact Map | 0.88 |
| 1ydyA | 2 | 0.9838 | 100 | 0.163 | Contact Map | 0.816 |
Sequence Conservation (Image Generated using WebLogo v3)