| UniProt: | P0AGL7 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12366 | ||
| Length: | 243 (240) | ||
| Sequences: | 1972 | ||
| Seq/Len: | 8.22 |
| RSME
Paralog alert: 0.06 [within 20: 0.00] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 135_A | 150_I | 4.229 | 1.00 | |
| 113_E | 202_D | 3.242 | 1.00 | |
| 113_E | 200_S | 3.15 | 1.00 | |
| 106_L | 151_R | 3.101 | 1.00 | |
| 96_I | 135_A | 2.986 | 1.00 | |
| 106_L | 149_E | 2.811 | 1.00 | |
| 81_H | 108_T | 2.714 | 1.00 | |
| 53_E | 67_L | 2.708 | 1.00 | |
| 53_E | 65_K | 2.68 | 1.00 | |
| 87_S | 224_T | 2.572 | 1.00 | |
| 99_S | 107_I | 2.555 | 1.00 | |
| 26_N | 30_R | 2.508 | 1.00 | |
| 83_G | 159_W | 2.436 | 1.00 | |
| 51_D | 68_E | 2.333 | 1.00 | |
| 55_T | 65_K | 2.32 | 1.00 | |
| 168_K | 212_F | 2.203 | 1.00 | |
| 83_G | 190_R | 2.167 | 1.00 | |
| 39_A | 53_E | 2.091 | 1.00 | |
| 170_N | 204_I | 2.056 | 1.00 | |
| 114_R | 200_S | 1.959 | 1.00 | |
| 52_A | 64_V | 1.948 | 1.00 | |
| 25_A | 62_V | 1.929 | 1.00 | |
| 39_A | 51_D | 1.886 | 1.00 | |
| 205_A | 209_R | 1.875 | 1.00 | |
| 24_A | 140_E | 1.873 | 1.00 | |
| 112_S | 115_C | 1.818 | 1.00 | |
| 79_H | 188_R | 1.764 | 1.00 | |
| 48_Q | 69_G | 1.744 | 1.00 | |
| 94_F | 98_K | 1.741 | 1.00 | |
| 155_D | 158_A | 1.736 | 1.00 | |
| 80_I | 232_I | 1.687 | 1.00 | |
| 83_G | 110_L | 1.684 | 1.00 | |
| 191_L | 231_A | 1.665 | 1.00 | |
| 85_V | 112_S | 1.646 | 1.00 | |
| 87_S | 95_T | 1.643 | 1.00 | |
| 156_L | 207_T | 1.637 | 1.00 | |
| 108_T | 151_R | 1.618 | 1.00 | |
| 56_S | 63_E | 1.616 | 1.00 | |
| 94_F | 229_L | 1.615 | 1.00 | |
| 109_P | 152_P | 1.603 | 1.00 | |
| 111_F | 153_A | 1.574 | 1.00 | |
| 96_I | 131_W | 1.564 | 1.00 | |
| 17_H | 63_E | 1.526 | 1.00 | |
| 28_I | 40_L | 1.525 | 1.00 | |
| 201_A | 205_A | 1.517 | 1.00 | |
| 170_N | 207_T | 1.51 | 1.00 | |
| 192_L | 212_F | 1.506 | 1.00 | |
| 28_I | 34_M | 1.495 | 1.00 | |
| 91_K | 95_T | 1.492 | 1.00 | |
| 128_L | 132_Q | 1.472 | 0.99 | |
| 96_I | 150_I | 1.444 | 0.99 | |
| 94_F | 97_Q | 1.443 | 0.99 | |
| 84_Q | 228_A | 1.441 | 0.99 | |
| 49_V | 145_N | 1.441 | 0.99 | |
| 79_H | 106_L | 1.429 | 0.99 | |
| 98_K | 225_E | 1.425 | 0.99 | |
| 82_L | 99_S | 1.424 | 0.99 | |
| 92_M | 131_W | 1.419 | 0.99 | |
| 44_D | 47_N | 1.415 | 0.99 | |
| 170_N | 199_L | 1.412 | 0.99 | |
| 172_H | 204_I | 1.411 | 0.99 | |
| 6_I | 28_I | 1.405 | 0.99 | |
| 79_H | 105_S | 1.39 | 0.99 | |
| 230_T | 233_T | 1.374 | 0.99 | |
| 110_L | 159_W | 1.342 | 0.99 | |
| 84_Q | 224_T | 1.341 | 0.99 | |
| 234_A | 237_V | 1.336 | 0.99 | |
| 192_L | 207_T | 1.331 | 0.99 | |
| 97_Q | 101_E | 1.328 | 0.99 | |
| 130_Q | 134_I | 1.318 | 0.99 | |
| 93_E | 130_Q | 1.307 | 0.98 | |
| 157_E | 206_M | 1.291 | 0.98 | |
| 37_G | 53_E | 1.264 | 0.98 | |
| 23_D | 133_K | 1.256 | 0.98 | |
| 91_K | 97_Q | 1.236 | 0.98 | |
| 22_E | 25_A | 1.234 | 0.98 | |
| 84_Q | 95_T | 1.208 | 0.97 | |
| 36_P | 56_S | 1.208 | 0.97 | |
| 102_L | 230_T | 1.19 | 0.97 | |
| 98_K | 101_E | 1.186 | 0.97 | |
| 76_S | 236_Q | 1.185 | 0.97 | |
| 51_D | 67_L | 1.185 | 0.97 | |
| 40_L | 64_V | 1.173 | 0.96 | |
| 104_V | 107_I | 1.17 | 0.96 | |
| 208_A | 214_D | 1.167 | 0.96 | |
| 34_M | 54_I | 1.144 | 0.96 | |
| 75_E | 144_R | 1.143 | 0.96 | |
| 6_I | 32_L | 1.137 | 0.95 | |
| 20_L | 28_I | 1.135 | 0.95 | |
| 26_N | 31_V | 1.129 | 0.95 | |
| 75_E | 146_R | 1.129 | 0.95 | |
| 41_Q | 49_V | 1.124 | 0.95 | |
| 54_I | 57_A | 1.119 | 0.95 | |
| 81_H | 106_L | 1.115 | 0.95 | |
| 101_E | 226_T | 1.114 | 0.95 | |
| 17_H | 65_K | 1.112 | 0.95 | |
| 39_A | 67_L | 1.11 | 0.95 | |
| 236_Q | 241_D | 1.105 | 0.94 | |
| 193_I | 224_T | 1.098 | 0.94 | |
| 139_C | 147_V | 1.097 | 0.94 | |
| 206_M | 210_Y | 1.088 | 0.94 | |
| 169_L | 215_I | 1.086 | 0.94 | |
| 92_M | 109_P | 1.084 | 0.94 | |
| 88_R | 116_G | 1.083 | 0.94 | |
| 100_I | 148_P | 1.077 | 0.93 | |
| 54_I | 62_V | 1.063 | 0.93 | |
| 160_C | 206_M | 1.059 | 0.93 | |
| 54_I | 64_V | 1.056 | 0.92 | |
| 104_V | 232_I | 1.055 | 0.92 | |
| 156_L | 160_C | 1.051 | 0.92 | |
| 20_L | 25_A | 1.041 | 0.92 | |
| 133_K | 137_A | 1.04 | 0.92 | |
| 76_S | 241_D | 1.039 | 0.92 | |
| 34_M | 38_Q | 1.032 | 0.91 | |
| 102_L | 233_T | 1.03 | 0.91 | |
| 24_A | 27_H | 1.029 | 0.91 | |
| 17_H | 55_T | 1.027 | 0.91 | |
| 42_L | 64_V | 1.026 | 0.91 | |
| 52_A | 66_V | 1.018 | 0.91 | |
| 236_Q | 240_G | 1.018 | 0.91 | |
| 189_V | 235_L | 1.016 | 0.90 | |
| 28_I | 62_V | 1.016 | 0.90 | |
| 206_M | 209_R | 1.014 | 0.90 | |
| 97_Q | 137_A | 1.009 | 0.90 | |
| 82_L | 104_V | 1.006 | 0.90 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 4e8bA | 1 | 1 | 100 | -0.008 | Contact Map | 0.746 |
| 1vhyA | 2 | 1 | 100 | -0.008 | Contact Map | 0.817 |
| 1vhkA | 4 | 1 | 100 | 0.008 | Contact Map | 0.88 |
| 4j3cA | 2 | 0.9712 | 100 | 0.039 | Contact Map | 0.785 |
| 1v6zA | 2 | 0.9383 | 100 | 0.061 | Contact Map | 0.801 |
| 3kw2A | 2 | 0.963 | 100 | 0.063 | Contact Map | 0.86 |
| 2egvA | 2 | 0.9342 | 100 | 0.076 | Contact Map | 0.694 |
| 1z85A | 2 | 0.9177 | 100 | 0.117 | Contact Map | 0.743 |
| 2qmmA | 2 | 0.7284 | 99.9 | 0.669 | Contact Map | 0.549 |
| 3aiaA | 2 | 0.7695 | 99.2 | 0.799 | Contact Map | 0.665 |
Sequence Conservation (Image Generated using WebLogo v3)