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YHBY - RNA-binding protein YhbY
UniProt: P0AGK4 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12794
Length: 97 (97)
Sequences: 679
Seq/Len: 7.00

YHBY
Paralog alert: 0.00 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
15_A 83_V 4.29 1.00
38_E 86_R 3.61 1.00
10_H 14_L 2.816 1.00
5_T 8_K 2.564 1.00
93_I 96_P 2.259 1.00
21_V 40_A 2.082 1.00
60_T 64_E 2.015 1.00
5_T 9_Q 1.867 1.00
59_K 80_K 1.712 1.00
65_A 69_E 1.692 1.00
22_V 33_V 1.66 1.00
37_I 66_I 1.638 1.00
67_V 84_L 1.586 1.00
12_K 76_Q 1.526 0.99
10_H 96_P 1.453 0.99
76_Q 83_V 1.401 0.99
42_E 88_T 1.394 0.99
78_I 83_V 1.386 0.99
9_Q 12_K 1.321 0.98
92_K 96_P 1.321 0.98
28_G 57_E 1.238 0.97
21_V 44_H 1.235 0.97
50_K 81_T 1.217 0.96
67_V 74_N 1.184 0.95
38_E 42_E 1.16 0.95
14_L 93_I 1.142 0.94
21_V 47_I 1.142 0.94
16_H 59_K 1.099 0.92
42_E 89_K 1.09 0.92
57_E 62_I 1.081 0.91
55_D 58_T 1.042 0.89
41_L 86_R 1.04 0.89
30_T 33_V 1.036 0.89
88_T 91_R 1.021 0.88
67_V 72_A 1.019 0.88
18_L 44_H 1.011 0.87
36_E 80_K 1.005 0.87
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1jo0A211000.097Contact Map0.72
1rq8A10.98971000.14Contact Map0.512
3sbxA80.628928.30.911Contact Map0.32
3quaA20.639219.40.918Contact Map0.237
3u5iq10.969115.80.921Contact Map0.149
1hsjA20.855712.30.925Contact Map0.394
1t35A80.762911.60.925Contact Map0.328
4j80A40.340210.30.927Contact Map0.782
4kix510.92788.40.93Contact Map0.125
4hubG10.95887.80.931Contact Map0.238

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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