May 4, 2021 - We are working on upgrading the webserver, some pages may not work.
OPENSEQ.org

SODC - Superoxide dismutase [Cu-Zn]
UniProt: P0AGD1 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG13419
Length: 173 (156)
Sequences: 868
Seq/Len: 5.56

SODC
Paralog alert: 0.18 [within 20: 0.02] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
101_H 104_P 2.961 1.00
60_P 167_Y 2.745 1.00
119_N 123_K 2.379 1.00
54_P 126_D 2.356 1.00
55_D 125_T 2.283 1.00
64_H 118_V 2.052 1.00
50_L 134_K 1.927 1.00
43_I 144_L 1.923 1.00
43_I 139_I 1.902 1.00
139_I 142_K 1.892 1.00
148_V 165_E 1.805 1.00
70_A 97_N 1.746 1.00
54_P 127_A 1.722 1.00
155_D 158_K 1.698 1.00
14_A 20_A 1.61 0.99
49_G 129_I 1.58 0.99
41_V 54_P 1.579 0.99
72_G 171_V 1.522 0.99
68_I 172_I 1.503 0.99
51_E 129_I 1.49 0.99
67_H 92_H 1.477 0.99
41_V 144_L 1.468 0.99
66_F 124_A 1.453 0.98
95_P 109_H 1.453 0.98
56_L 65_G 1.451 0.98
51_E 127_A 1.429 0.98
43_I 172_I 1.412 0.98
65_G 116_L 1.408 0.98
63_E 117_V 1.408 0.98
78_T 83_A 1.385 0.98
43_I 52_F 1.377 0.98
89_A 143_A 1.373 0.98
93_L 110_L 1.366 0.97
113_L 130_A 1.333 0.97
116_L 124_A 1.331 0.97
161_G 164_G 1.329 0.97
136_L 139_I 1.311 0.97
98_T 107_A 1.288 0.96
68_I 144_L 1.277 0.96
65_G 163_G 1.274 0.96
100_K 104_P 1.253 0.95
46_T 51_E 1.25 0.95
115_A 153_M 1.249 0.95
160_L 163_G 1.248 0.95
14_A 21_S 1.225 0.94
74_C 143_A 1.219 0.94
151_D 161_G 1.201 0.94
118_V 123_K 1.197 0.93
45_E 135_S 1.184 0.93
50_L 133_L 1.183 0.93
115_A 152_N 1.174 0.93
93_L 142_K 1.164 0.92
74_C 169_C 1.158 0.92
156_Q 159_P 1.158 0.92
62_G 118_V 1.153 0.92
15_T 21_S 1.136 0.91
48_K 156_Q 1.125 0.90
74_C 159_P 1.109 0.89
99_G 107_A 1.105 0.89
29_V 86_A 1.1 0.89
15_T 22_E 1.096 0.89
56_L 116_L 1.07 0.87
77_A 83_A 1.066 0.87
86_A 142_K 1.063 0.87
62_G 156_Q 1.034 0.84
45_E 50_L 1.022 0.84
94_D 98_T 1.012 0.83
14_A 22_E 1.006 0.82
38_I 168_A 1 0.82
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1z9nA40.98271000.17Contact Map0.682
1esoA10.88441000.195Contact Map0.64
1eqwA40.88441000.198Contact Map0.65
2aqmA10.88441000.201Contact Map0.627
1oalA10.86711000.206Contact Map0.667
2aqpA20.93641000.213Contact Map0.691
1pzsA10.9481000.246Contact Map0.604
3pu7A20.80921000.25Contact Map0.676
1to4A40.8151000.253Contact Map0.64
2q2lA20.80351000.253Contact Map0.67

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0227 seconds.