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OPENSEQ.org

RL21 - 50S ribosomal protein L21
UniProt: P0AG48 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG50001
Length: 103 (103)
Sequences: 1409
Seq/Len: 13.68

RL21
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
62_E 99_T 3.737 1.00
28_A 31_E 3.575 1.00
16_E 100_G 3.448 1.00
6_Q 37_E 3.354 1.00
68_R 92_W 3.27 1.00
27_I 63_V 3.218 1.00
73_K 86_Q 2.797 1.00
15_S 18_Q 2.597 1.00
34_E 58_V 2.552 1.00
61_A 98_I 2.458 1.00
62_E 97_K 2.414 1.00
21_R 95_D 2.274 1.00
32_T 60_K 2.079 1.00
78_R 83_Y 2.031 1.00
22_L 96_V 2.005 1.00
35_F 96_V 1.94 1.00
40_M 47_V 1.884 1.00
19_T 95_D 1.871 1.00
58_V 102_S 1.828 1.00
7_S 22_L 1.815 1.00
10_K 23_E 1.809 1.00
77_F 80_R 1.794 1.00
61_A 96_V 1.723 1.00
65_A 95_D 1.538 1.00
6_Q 53_F 1.533 1.00
34_E 60_K 1.5 1.00
5_F 35_F 1.449 1.00
7_S 23_E 1.405 0.99
40_M 49_I 1.394 0.99
67_G 93_F 1.352 0.99
21_R 69_G 1.319 0.99
64_V 97_K 1.314 0.99
19_T 97_K 1.304 0.99
74_I 87_Q 1.291 0.99
76_K 83_Y 1.256 0.99
74_I 83_Y 1.235 0.98
49_I 52_P 1.232 0.98
75_V 86_Q 1.231 0.98
27_I 31_E 1.228 0.98
43_N 46_E 1.209 0.98
35_F 61_A 1.191 0.98
52_P 56_G 1.178 0.98
60_K 100_G 1.175 0.98
32_T 99_T 1.175 0.98
54_V 57_G 1.162 0.97
20_V 96_V 1.154 0.97
75_V 84_R 1.141 0.97
7_S 12_H 1.123 0.97
37_E 53_F 1.048 0.94
29_T 65_A 1.024 0.93
5_F 59_I 1.008 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3bboT111000.02Contact Map0.608
4kixR111000.036Contact Map0.773
3j3wR10.99031000.049Contact Map0.797
3v2dV10.98061000.056Contact Map0.792
2zjrO10.97091000.082Contact Map0.305
2xhaA20.815568.50.888Contact Map0.036
2y4xA20.543723.50.916Contact Map0.354
4av2M120.679612.90.925Contact Map0.433
2ivwA10.679611.60.927Contact Map0.43
3ossC10.456310.80.928Contact Map0.384

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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