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OPENSEQ.org
YHID - Uncharacterized protein YhiD
UniProt: P0AFV2 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11400
Length: 215 (213)
Sequences: 692
Seq/Len: 3.25
YHID
Paralog alert: 0.19 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
12_A 43_A 3.835 1.00
45_F 106_A 3.106 1.00
73_V 109_M 2.781 1.00
16_C 39_G 2.65 1.00
72_Q 75_T 2.261 1.00
44_L 122_G 2.052 1.00
111_I 119_G 1.99 1.00
15_A 111_I 1.955 1.00
17_G 32_L 1.874 0.99
17_G 36_V 1.79 0.99
35_H 100_D 1.787 0.99
70_A 106_A 1.77 0.99
13_A 36_V 1.711 0.99
41_G 72_Q 1.709 0.99
64_L 67_S 1.69 0.99
6_I 121_Y 1.678 0.98
128_L 132_V 1.661 0.98
71_A 75_T 1.637 0.98
37_L 41_G 1.634 0.98
103_V 126_T 1.584 0.98
46_M 109_M 1.542 0.97
15_A 123_S 1.489 0.96
70_A 74_V 1.464 0.96
44_L 49_S 1.458 0.95
69_I 115_M 1.414 0.94
49_S 70_A 1.403 0.94
19_I 107_I 1.397 0.94
36_V 129_V 1.387 0.94
209_V 212_V 1.385 0.94
35_H 130_L 1.368 0.93
69_I 74_V 1.364 0.93
170_T 173_V 1.362 0.93
41_G 103_V 1.352 0.92
84_N 109_M 1.352 0.92
6_I 10_I 1.344 0.92
45_F 111_I 1.319 0.91
50_K 55_D 1.317 0.91
18_A 212_V 1.315 0.91
15_A 119_G 1.291 0.90
100_D 104_T 1.268 0.89
37_L 93_V 1.267 0.89
9_L 121_Y 1.265 0.89
67_S 87_V 1.26 0.88
48_V 126_T 1.26 0.88
82_A 86_L 1.257 0.88
111_I 116_Y 1.249 0.88
21_M 127_L 1.226 0.87
92_I 129_V 1.226 0.87
74_V 106_A 1.226 0.87
42_S 66_P 1.218 0.86
8_R 114_G 1.205 0.85
30_A 100_D 1.197 0.85
89_N 100_D 1.194 0.85
75_T 105_A 1.19 0.84
96_T 130_L 1.19 0.84
38_I 100_D 1.189 0.84
45_F 69_I 1.187 0.84
96_T 109_M 1.182 0.84
49_S 72_Q 1.18 0.84
152_V 210_K 1.172 0.83
46_M 113_S 1.154 0.82
37_L 130_L 1.153 0.82
30_A 38_I 1.151 0.81
76_G 105_A 1.148 0.81
129_V 136_L 1.143 0.81
42_S 105_A 1.129 0.80
84_N 101_I 1.119 0.79
18_A 54_A 1.118 0.79
8_R 38_I 1.117 0.79
35_H 104_T 1.115 0.79
28_K 64_L 1.113 0.78
52_G 70_A 1.103 0.77
48_V 113_S 1.097 0.77
7_I 154_G 1.091 0.76
195_S 204_K 1.091 0.76
45_F 75_T 1.084 0.76
95_L 105_A 1.083 0.76
40_M 75_T 1.074 0.75
107_I 123_S 1.071 0.74
72_Q 105_A 1.066 0.74
8_R 84_N 1.066 0.74
71_A 74_V 1.066 0.74
49_S 66_P 1.065 0.74
45_F 74_V 1.052 0.73
65_D 68_R 1.049 0.72
33_R 123_S 1.046 0.72
124_V 178_N 1.039 0.71
18_A 127_L 1.038 0.71
49_S 113_S 1.033 0.71
88_R 93_V 1.029 0.70
35_H 38_I 1.028 0.70
37_L 101_I 1.024 0.70
52_G 55_D 1.017 0.69
26_R 88_R 1.015 0.69
28_K 48_V 1.013 0.69
30_A 41_G 1.006 0.68
86_L 104_T 1.005 0.68
24_Q 134_H 1.004 0.68
67_S 115_M 1.004 0.68
163_F 168_I 1.003 0.67
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2lqjA10.367494.20.913Contact Map0.818
2ko1A20.348892.60.918Contact Map0.625
1y7pA30.3349910.921Contact Map1
1zpvA30.353590.40.923Contact Map0.43
2lvwA20.353586.90.927Contact Map0.639
2pc6A40.344284.30.93Contact Map0.815
2f1fA20.339582.70.931Contact Map0.815
2fgcA10.395341.60.948Contact Map0.762
3n0vA40.367439.50.949Contact Map0.726
3obiA40.358138.10.949Contact Map0.653
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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