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OPENSEQ.org
PNUC - Nicotinamide riboside transporter PnuC
UniProt: P0AFK2 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11700
Length: 239 (212)
Sequences: 641
Seq/Len: 3.02
PNUC
Paralog alert: 0.10 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
43_E 180_K 2.87 1.00
70_S 202_Q 2.76 1.00
58_F 207_M 2.697 1.00
52_L 78_F 1.989 1.00
65_I 204_V 1.973 1.00
186_L 222_S 1.934 0.99
124_T 161_F 1.928 0.99
61_I 65_I 1.854 0.99
30_T 206_A 1.74 0.99
192_N 218_A 1.724 0.99
182_V 229_A 1.715 0.98
40_A 47_N 1.712 0.98
37_I 214_L 1.671 0.98
83_Y 178_T 1.662 0.98
223_R 227_N 1.615 0.98
200_A 208_S 1.604 0.97
25_I 57_L 1.588 0.97
216_F 219_L 1.544 0.97
36_C 47_N 1.536 0.96
212_I 216_F 1.529 0.96
82_I 86_Y 1.512 0.96
69_A 164_S 1.497 0.96
150_V 154_L 1.476 0.95
104_L 108_K 1.467 0.95
33_G 54_N 1.421 0.94
170_S 191_I 1.411 0.93
32_A 54_N 1.406 0.93
69_A 151_M 1.396 0.93
192_N 215_T 1.395 0.93
219_L 223_R 1.387 0.93
188_W 192_N 1.386 0.93
126_F 129_P 1.38 0.92
32_A 36_C 1.376 0.92
33_G 36_C 1.348 0.91
46_S 49_F 1.347 0.91
49_F 85_W 1.342 0.91
166_M 195_S 1.315 0.90
149_V 153_E 1.302 0.89
105_P 108_K 1.285 0.88
36_C 214_L 1.279 0.88
189_V 218_A 1.278 0.88
159_F 198_I 1.27 0.88
149_V 154_L 1.269 0.88
51_G 81_N 1.256 0.87
33_G 177_M 1.255 0.87
157_D 160_P 1.248 0.86
39_L 50_F 1.243 0.86
69_A 72_L 1.243 0.86
206_A 210_E 1.24 0.86
70_S 199_F 1.234 0.86
36_C 51_G 1.224 0.85
30_T 54_N 1.212 0.84
156_P 204_V 1.197 0.83
43_E 99_L 1.196 0.83
52_L 85_W 1.192 0.83
68_Y 156_P 1.187 0.82
43_E 101_I 1.18 0.82
104_L 109_A 1.171 0.81
158_A 202_Q 1.167 0.81
47_N 187_L 1.162 0.81
176_L 218_A 1.151 0.80
86_Y 89_S 1.149 0.79
87_A 90_R 1.14 0.79
99_L 180_K 1.135 0.78
48_Y 174_M 1.129 0.78
173_A 187_L 1.128 0.78
192_N 195_S 1.128 0.78
106_L 110_L 1.123 0.77
134_L 146_G 1.115 0.77
61_I 180_K 1.108 0.76
40_A 184_N 1.107 0.76
75_V 192_N 1.107 0.76
36_C 54_N 1.105 0.76
55_V 74_Q 1.103 0.76
73_L 167_M 1.101 0.75
15_I 134_L 1.097 0.75
54_N 80_A 1.088 0.74
36_C 77_F 1.087 0.74
105_P 118_V 1.086 0.74
55_V 81_N 1.079 0.73
17_A 133_F 1.077 0.73
56_T 78_F 1.077 0.73
172_V 176_L 1.075 0.73
196_V 212_I 1.07 0.72
32_A 192_N 1.065 0.72
102_R 229_A 1.059 0.71
101_I 228_S 1.056 0.71
66_Q 158_A 1.056 0.71
36_C 81_N 1.055 0.71
121_G 124_T 1.051 0.70
107_P 111_S 1.048 0.70
69_A 157_D 1.045 0.70
51_G 177_M 1.044 0.70
159_F 201_L 1.042 0.69
209_L 212_I 1.03 0.68
151_M 155_Q 1.028 0.68
60_I 64_Q 1.027 0.68
189_V 222_S 1.027 0.68
120_I 124_T 1.025 0.68
192_N 201_L 1.022 0.67
144_A 148_Q 1.019 0.67
208_S 212_I 1.019 0.67
150_V 153_E 1.015 0.67
37_I 171_I 1.014 0.66
51_G 54_N 1.004 0.65
77_F 166_M 1.003 0.65
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results:
PDB Chains Cov P(%) HHΔ   Acc
2qtsA60.2512.60.972Contact Map0.268
1rzhM10.3181.60.975Contact Map0.119
4cadC40.2511.30.976Contact Map0.186
2l5bA10.133910.977Contact Map0.411
4b1yM10.05860.90.979Contact Map
3bz1y10.15060.80.979Contact Map0.89
2m7gA10.17150.80.979Contact Map0.129
2l8sA10.19670.70.979Contact Map0.238
3l1lA10.43930.70.979Contact Map0.183
3dinD20.25940.70.98Contact Map0.087
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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