| UniProt: | P0AFI7 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG11487 | ||
| Length: | 218 (210) | ||
| Sequences: | 1201 | ||
| Seq/Len: | 5.72 |
| PDXH
Paralog alert: 0.07 [within 20: 0.01] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 127_M | 174_L | 3.84 | 1.00 | |
| 99_V | 118_A | 3.161 | 1.00 | |
| 151_S | 155_I | 3.148 | 1.00 | |
| 54_V | 66_Q | 3.065 | 1.00 | |
| 93_I | 99_V | 2.917 | 1.00 | |
| 28_P | 34_L | 2.821 | 1.00 | |
| 135_R | 138_Q | 2.782 | 1.00 | |
| 101_L | 183_V | 2.516 | 1.00 | |
| 145_K | 217_A | 2.493 | 1.00 | |
| 119_E | 184_S | 2.414 | 1.00 | |
| 56_A | 66_Q | 2.277 | 1.00 | |
| 65_Y | 92_Q | 2.24 | 1.00 | |
| 63_Q | 98_R | 2.206 | 1.00 | |
| 53_M | 101_L | 2.187 | 1.00 | |
| 135_R | 172_V | 2.072 | 1.00 | |
| 65_Y | 88_R | 2.048 | 1.00 | |
| 65_Y | 115_I | 2.022 | 1.00 | |
| 66_Q | 102_L | 2 | 1.00 | |
| 99_V | 183_V | 1.997 | 1.00 | |
| 63_Q | 186_E | 1.98 | 1.00 | |
| 85_L | 120_R | 1.966 | 1.00 | |
| 149_R | 214_D | 1.93 | 1.00 | |
| 123_T | 174_L | 1.908 | 1.00 | |
| 187_Q | 203_L | 1.817 | 1.00 | |
| 115_I | 187_Q | 1.791 | 1.00 | |
| 85_L | 126_V | 1.777 | 1.00 | |
| 139_I | 160_F | 1.777 | 1.00 | |
| 93_I | 118_A | 1.765 | 1.00 | |
| 54_V | 68_I | 1.722 | 1.00 | |
| 159_K | 162_E | 1.702 | 1.00 | |
| 24_R | 202_F | 1.692 | 1.00 | |
| 60_E | 95_N | 1.686 | 1.00 | |
| 85_L | 179_G | 1.681 | 1.00 | |
| 35_F | 79_M | 1.679 | 1.00 | |
| 88_R | 115_I | 1.669 | 1.00 | |
| 27_L | 202_F | 1.658 | 1.00 | |
| 205_Q | 214_D | 1.643 | 1.00 | |
| 94_E | 181_F | 1.642 | 1.00 | |
| 86_G | 148_S | 1.623 | 0.99 | |
| 36_E | 74_Y | 1.622 | 0.99 | |
| 55_V | 99_V | 1.573 | 0.99 | |
| 203_L | 214_D | 1.562 | 0.99 | |
| 36_E | 40_S | 1.544 | 0.99 | |
| 123_T | 127_M | 1.518 | 0.99 | |
| 200_D | 215_R | 1.49 | 0.99 | |
| 88_R | 92_Q | 1.479 | 0.99 | |
| 117_K | 186_E | 1.471 | 0.99 | |
| 40_S | 44_E | 1.457 | 0.99 | |
| 205_Q | 212_K | 1.433 | 0.98 | |
| 63_Q | 115_I | 1.431 | 0.98 | |
| 202_F | 213_I | 1.423 | 0.98 | |
| 75_D | 182_R | 1.42 | 0.98 | |
| 9_Q | 12_H | 1.412 | 0.98 | |
| 75_D | 78_G | 1.4 | 0.98 | |
| 125_E | 182_R | 1.375 | 0.98 | |
| 142_W | 167_F | 1.37 | 0.98 | |
| 84_N | 177_F | 1.358 | 0.97 | |
| 39_L | 51_T | 1.315 | 0.97 | |
| 118_A | 183_V | 1.288 | 0.96 | |
| 122_S | 125_E | 1.285 | 0.96 | |
| 167_F | 173_P | 1.279 | 0.96 | |
| 158_S | 162_E | 1.276 | 0.96 | |
| 79_M | 188_I | 1.274 | 0.96 | |
| 145_K | 159_K | 1.242 | 0.95 | |
| 142_W | 177_F | 1.24 | 0.95 | |
| 149_R | 217_A | 1.239 | 0.95 | |
| 126_V | 179_G | 1.219 | 0.94 | |
| 142_W | 176_S | 1.213 | 0.94 | |
| 162_E | 166_K | 1.208 | 0.94 | |
| 58_V | 98_R | 1.195 | 0.94 | |
| 80_V | 121_L | 1.194 | 0.94 | |
| 19_K | 109_E | 1.19 | 0.93 | |
| 117_K | 184_S | 1.185 | 0.93 | |
| 30_D | 33_T | 1.184 | 0.93 | |
| 82_Y | 121_L | 1.184 | 0.93 | |
| 32_L | 188_I | 1.18 | 0.93 | |
| 80_V | 182_R | 1.179 | 0.93 | |
| 131_H | 138_Q | 1.179 | 0.93 | |
| 38_W | 110_R | 1.178 | 0.93 | |
| 27_L | 213_I | 1.177 | 0.93 | |
| 163_L | 167_F | 1.174 | 0.93 | |
| 145_K | 148_S | 1.166 | 0.93 | |
| 98_R | 186_E | 1.128 | 0.91 | |
| 142_W | 163_L | 1.109 | 0.90 | |
| 78_G | 182_R | 1.083 | 0.88 | |
| 77_K | 125_E | 1.077 | 0.88 | |
| 35_F | 39_L | 1.074 | 0.88 | |
| 14_R | 17_Y | 1.071 | 0.88 | |
| 18_T | 21_G | 1.071 | 0.88 | |
| 100_S | 113_M | 1.068 | 0.87 | |
| 161_L | 165_Q | 1.063 | 0.87 | |
| 130_F | 138_Q | 1.061 | 0.87 | |
| 35_F | 112_V | 1.055 | 0.87 | |
| 55_V | 183_V | 1.054 | 0.87 | |
| 154_G | 158_S | 1.052 | 0.86 | |
| 157_E | 194_G | 1.051 | 0.86 | |
| 136_D | 196_H | 1.048 | 0.86 | |
| 31_P | 38_W | 1.044 | 0.86 | |
| 71_L | 79_M | 1.037 | 0.85 | |
| 136_D | 164_K | 1.033 | 0.85 | |
| 58_V | 95_N | 1.024 | 0.84 | |
| 68_I | 113_M | 1.016 | 0.84 | |
| 161_L | 164_K | 1.014 | 0.84 | |
| 165_Q | 168_Q | 1.01 | 0.83 | |
| 58_V | 96_N | 1.008 | 0.83 | |
| 94_E | 120_R | 1.003 | 0.83 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1nrgA | 1 | 1 | 100 | 0.249 | Contact Map | 0.671 |
| 1ci0A | 2 | 1 | 100 | 0.249 | Contact Map | 0.786 |
| 2a2jA | 2 | 0.9771 | 100 | 0.256 | Contact Map | 0.705 |
| 4hmsA | 2 | 0.9908 | 100 | 0.29 | Contact Map | 0.654 |
| 1ty9A | 2 | 0.9908 | 100 | 0.294 | Contact Map | 0.646 |
| 4hmwA | 2 | 0.9862 | 100 | 0.302 | Contact Map | 0.721 |
| 1dnlA | 1 | 0.9128 | 100 | 0.329 | Contact Map | 0.67 |
| 2i51A | 2 | 0.8303 | 100 | 0.465 | Contact Map | 0.451 |
| 2ou5A | 2 | 0.7844 | 100 | 0.59 | Contact Map | 0.625 |
| 3u35A | 4 | 0.7752 | 99.8 | 0.751 | Contact Map | 0.542 |
Sequence Conservation (Image Generated using WebLogo v3)