OPENSEQ.org - YJCH - ECOLI GREMLIN

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YJCH - Inner membrane protein YjcH

UniProt:	P0AF54	Sequence MNGTIYQRIEDNAHFRELVEKRQRFATILSIIMLAVYIGFILLIAFAPGWLGTPLNPNTSVTRGIPIGVGVIVISFVLTGIYIWRANGEFDRLNNEVLHEVQAS	Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene:	EG11943
Length:	104 (103)
Sequences:	517
Seq/Len:	5.02

YJCH
Paralog alert: 0.08 [within 20: 0.01] - ratio of genomes with paralogs

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Scaled Score	Prob
14_H	96_E	2.52	1.00
36_V	71_V	2.493	1.00
36_V	74_I	2.47	1.00
17_E	21_K	2.348	1.00
56_N	59_T	2.175	1.00
14_H	100_E	1.827	1.00
25_F	85_R	1.613	0.99
95_N	99_H	1.6	0.99
64_G	87_N	1.566	0.99
47_A	50_W	1.55	0.99
11_D	16_R	1.528	0.99
23_Q	27_T	1.524	0.99
85_R	90_F	1.519	0.99
92_R	96_E	1.513	0.99
27_T	31_I	1.511	0.99
55_L	63_R	1.508	0.99
21_K	89_E	1.461	0.98
72_I	75_S	1.366	0.97
88_G	92_R	1.325	0.96
95_N	98_L	1.314	0.96
20_E	24_R	1.312	0.96
72_I	80_G	1.295	0.95
17_E	93_L	1.281	0.95
68_G	76_F	1.278	0.95
43_L	67_I	1.247	0.94
35_A	53_T	1.225	0.93
35_A	39_G	1.21	0.93
77_V	80_G	1.196	0.92
6_Y	15_F	1.196	0.92
9_I	101_V	1.195	0.92
66_P	70_G	1.193	0.92
29_L	87_N	1.176	0.91
58_N	61_V	1.153	0.90
73_V	77_V	1.138	0.89
79_T	83_I	1.133	0.89
96_E	99_H	1.105	0.87
9_I	32_I	1.089	0.86
7_Q	11_D	1.088	0.86
13_A	16_R	1.057	0.84
46_F	97_V	1.054	0.84
85_R	89_E	1.049	0.83
22_R	26_A	1.047	0.83
43_L	50_W	1.037	0.82
31_I	35_A	1.036	0.82

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling

HHsearch Results:

PDB	Chains	Cov	P(%)	HHΔ		Acc
4hkrA	2	0.9423	26.1	0.907	Contact Map	0.313
2z73A	2	1	13.9	0.918	Contact Map	0.24
2m20A	2	0.4615	13	0.919	Contact Map	0.367
3kkeA	4	0.4231	8.6	0.925	Contact Map	0.434
2dlrA	1	0.3365	7.1	0.928	Contact Map	0.471
4i0uA	10	0.8269	7.1	0.928	Contact Map	0.453
4djkA	2	0.9135	6.7	0.929	Contact Map	0.228
4jrbA	1	0.3846	6.5	0.929	Contact Map	0.426
3tb6A	2	0.4231	6.5	0.929	Contact Map	0.45
4gycB	1	0.9135	6.3	0.93	Contact Map	0.41

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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