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OPENSEQ.org
YJBB - Uncharacterized protein YjbB
UniProt: P0AF43 Sequence
 Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11919
Length: 543 (532)
Sequences: 838
Seq/Len: 1.58
YJBB
Paralog alert: 0.10 [within 20: 0.01] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
98_R 277_Y 3.933 1.00
98_R 273_E 2.964 1.00
343_G 459_M 2.751 1.00
341_R 377_L 2.484 1.00
412_E 416_D 2.476 1.00
62_N 220_S 2.409 1.00
217_N 283_N 2.368 1.00
273_E 277_Y 2.286 0.99
477_K 481_R 2.273 0.99
90_D 246_K 2.197 0.99
335_A 385_L 2.156 0.99
220_S 223_L 2.115 0.99
477_K 517_Q 2.086 0.99
48_F 91_V 2.035 0.98
45_P 291_L 2.017 0.98
175_A 254_L 1.993 0.98
375_N 416_D 1.975 0.98
375_N 412_E 1.969 0.98
98_R 280_V 1.909 0.97
12_A 113_F 1.907 0.97
12_A 116_V 1.887 0.97
222_L 225_M 1.877 0.97
91_V 284_L 1.857 0.97
102_F 273_E 1.854 0.97
43_K 46_L 1.841 0.97
225_M 243_L 1.831 0.96
83_L 298_A 1.812 0.96
443_E 494_R 1.802 0.96
374_I 415_S 1.801 0.96
319_H 338_E 1.797 0.96
83_L 241_G 1.788 0.96
279_H 283_N 1.781 0.96
296_P 300_F 1.769 0.95
477_K 521_S 1.756 0.95
214_I 250_S 1.712 0.94
48_F 287_C 1.696 0.94
67_L 71_F 1.679 0.94
440_G 494_R 1.657 0.93
371_A 416_D 1.651 0.93
86_V 242_S 1.633 0.92
83_L 99_I 1.626 0.92
491_H 494_R 1.623 0.92
371_A 412_E 1.611 0.92
440_G 509_H 1.601 0.91
96_M 189_L 1.599 0.91
55_T 64_T 1.57 0.90
518_R 522_L 1.566 0.90
220_S 242_S 1.564 0.90
48_F 291_L 1.547 0.89
412_E 415_S 1.547 0.89
321_D 328_P 1.516 0.88
16_W 20_I 1.515 0.88
91_V 287_C 1.511 0.88
517_Q 521_S 1.51 0.88
112_I 142_L 1.505 0.87
158_N 162_V 1.493 0.87
377_L 381_I 1.485 0.86
237_R 302_K 1.483 0.86
10_A 143_A 1.479 0.86
87_L 290_M 1.479 0.86
371_A 375_N 1.477 0.86
98_R 101_T 1.477 0.86
437_S 494_R 1.476 0.86
470_A 531_L 1.473 0.86
182_A 282_Y 1.466 0.85
8_L 113_F 1.443 0.84
249_G 286_R 1.44 0.84
48_F 64_T 1.432 0.84
94_A 280_V 1.431 0.84
481_R 521_S 1.422 0.83
87_L 287_C 1.422 0.83
42_E 46_L 1.412 0.82
62_N 222_L 1.409 0.82
103_D 222_L 1.398 0.82
288_L 291_L 1.396 0.81
517_Q 520_N 1.388 0.81
10_A 14_L 1.384 0.81
62_N 224_A 1.382 0.81
37_L 375_N 1.38 0.80
65_T 86_V 1.38 0.80
248_V 293_F 1.371 0.80
112_I 138_G 1.364 0.79
454_N 520_N 1.363 0.79
346_M 411_L 1.362 0.79
296_P 299_R 1.357 0.79
375_N 428_K 1.352 0.79
24_G 33_L 1.347 0.78
410_N 417_I 1.338 0.78
195_T 212_L 1.337 0.77
196_A 276_I 1.334 0.77
346_M 374_I 1.331 0.77
440_G 491_H 1.331 0.77
317_P 377_L 1.329 0.77
217_N 279_H 1.321 0.76
220_S 283_N 1.319 0.76
33_L 511_G 1.308 0.75
214_I 249_G 1.301 0.75
18_T 280_V 1.301 0.75
94_A 220_S 1.301 0.75
481_R 517_Q 1.297 0.74
443_E 490_A 1.297 0.74
79_L 82_A 1.293 0.74
298_A 302_K 1.284 0.73
506_S 509_H 1.265 0.72
37_L 181_F 1.265 0.72
216_A 257_V 1.263 0.72
242_S 282_Y 1.26 0.71
299_R 303_T 1.259 0.71
317_P 380_A 1.258 0.71
54_V 64_T 1.256 0.71
9_S 235_A 1.256 0.71
109_P 243_L 1.255 0.71
427_D 431_A 1.249 0.70
76_L 227_N 1.249 0.70
335_A 404_I 1.248 0.70
115_G 131_G 1.246 0.70
336_A 400_R 1.237 0.69
461_V 473_L 1.233 0.69
118_F 124_Q 1.228 0.68
217_N 245_F 1.226 0.68
181_F 214_I 1.22 0.68
280_V 284_L 1.217 0.67
319_H 341_R 1.214 0.67
213_V 253_I 1.212 0.67
451_L 516_M 1.209 0.67
14_L 186_Y 1.208 0.67
422_G 512_L 1.205 0.66
371_A 521_S 1.204 0.66
19_H 23_T 1.2 0.66
319_H 377_L 1.198 0.66
288_L 292_P 1.196 0.66
93_T 189_L 1.195 0.65
65_T 242_S 1.194 0.65
83_L 294_V 1.194 0.65
4_L 332_L 1.192 0.65
86_V 238_V 1.189 0.65
206_F 274_L 1.188 0.65
71_F 142_L 1.187 0.65
18_T 71_F 1.177 0.64
410_N 525_S 1.176 0.64
114_I 118_F 1.175 0.63
34_R 144_L 1.172 0.63
338_E 341_R 1.167 0.63
94_A 276_I 1.166 0.63
72_V 82_A 1.163 0.62
113_F 116_V 1.161 0.62
174_D 195_T 1.158 0.62
101_T 277_Y 1.157 0.62
195_T 216_A 1.153 0.61
223_L 242_S 1.15 0.61
290_M 297_M 1.148 0.61
352_G 370_L 1.145 0.61
87_L 286_R 1.144 0.60
25_V 29_F 1.142 0.60
55_T 61_S 1.14 0.60
320_L 331_A 1.138 0.60
78_A 81_P 1.129 0.59
188_S 217_N 1.128 0.59
74_Q 100_L 1.127 0.59
242_S 283_N 1.126 0.59
182_A 191_A 1.125 0.59
224_A 242_S 1.118 0.58
180_M 228_N 1.118 0.58
44_K 211_C 1.118 0.58
24_G 28_V 1.117 0.58
27_R 132_R 1.116 0.58
150_A 184_I 1.115 0.57
183_I 221_G 1.114 0.57
62_N 186_Y 1.113 0.57
491_H 509_H 1.112 0.57
440_G 500_V 1.108 0.57
183_I 222_L 1.107 0.57
300_F 304_I 1.107 0.57
104_L 221_G 1.106 0.57
17_G 143_A 1.105 0.56
186_Y 189_L 1.1 0.56
359_G 430_L 1.095 0.55
328_P 331_A 1.095 0.55
413_Q 522_L 1.094 0.55
225_M 228_N 1.093 0.55
284_L 288_L 1.093 0.55
321_D 331_A 1.093 0.55
436_F 491_H 1.091 0.55
5_L 144_L 1.089 0.55
291_L 294_V 1.088 0.55
93_T 371_A 1.087 0.55
116_V 121_G 1.085 0.54
204_I 209_A 1.085 0.54
242_S 246_K 1.082 0.54
63_A 71_F 1.082 0.54
443_E 491_H 1.081 0.54
342_I 381_I 1.077 0.54
24_G 136_G 1.076 0.53
147_I 174_D 1.07 0.53
407_M 526_V 1.069 0.53
49_C 52_I 1.068 0.53
72_V 178_G 1.068 0.53
288_L 295_D 1.066 0.52
188_S 283_N 1.062 0.52
77_V 81_P 1.062 0.52
94_A 242_S 1.061 0.52
174_D 212_L 1.059 0.52
140_I 147_I 1.058 0.52
230_A 357_M 1.056 0.51
437_S 440_G 1.055 0.51
90_D 242_S 1.053 0.51
461_V 470_A 1.051 0.51
64_T 71_F 1.051 0.51
355_K 363_Q 1.05 0.51
184_I 361_P 1.05 0.51
77_V 177_I 1.05 0.51
521_S 525_S 1.049 0.51
49_C 53_G 1.048 0.51
56_A 82_A 1.045 0.50
7_L 151_V 1.045 0.50
206_F 210_L 1.045 0.50
177_I 289_V 1.045 0.50
421_M 424_E 1.042 0.50
68_V 238_V 1.04 0.50
90_D 96_M 1.038 0.49
39_R 42_E 1.038 0.49
349_M 374_I 1.036 0.49
191_A 216_A 1.036 0.49
45_P 296_P 1.035 0.49
98_R 276_I 1.034 0.49
14_L 62_N 1.034 0.49
71_F 98_R 1.034 0.49
58_V 133_V 1.031 0.49
195_T 253_I 1.031 0.49
349_M 418_V 1.03 0.49
223_L 246_K 1.03 0.49
217_N 282_Y 1.027 0.48
240_L 305_I 1.025 0.48
295_D 299_R 1.025 0.48
338_E 381_I 1.024 0.48
457_L 472_R 1.023 0.48
85_I 113_F 1.023 0.48
375_N 415_S 1.023 0.48
288_L 366_E 1.022 0.48
55_T 96_M 1.021 0.48
65_T 235_A 1.021 0.48
241_G 301_C 1.019 0.47
342_I 416_D 1.019 0.47
142_L 146_L 1.019 0.47
58_V 189_L 1.019 0.47
507_S 510_L 1.019 0.47
194_L 320_L 1.018 0.47
126_R 288_L 1.018 0.47
85_I 140_I 1.017 0.47
55_T 90_D 1.016 0.47
15_V 85_I 1.016 0.47
144_L 197_T 1.012 0.47
213_V 216_A 1.011 0.47
68_V 71_F 1.009 0.46
421_M 477_K 1.008 0.46
100_L 109_P 1.008 0.46
58_V 62_N 1.006 0.46
293_F 296_P 1.005 0.46
112_I 181_F 1.004 0.46
371_A 415_S 1.002 0.46
57_L 189_L 1.002 0.46
41_V 97_A 1.001 0.46
50_A 375_N 1 0.45
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1sumB10.39591000.821Contact Map0.702
1xwmA10.39411000.822Contact Map0.552
2i0mA10.39041000.822Contact Map0.699
1t72A60.403399.90.828Contact Map0.723
2oltA30.379499.70.883Contact Map0.401
3l39A10.40799.10.919Contact Map0.453
1vctA10.211866.20.973Contact Map0.58
4f35D40.412554.20.975Contact Map0.27
2ld6A10.237629.20.979Contact Map0.364
3kyjA10.246829.10.979Contact Map0.267
Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.
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