| UniProt: | P0AF24 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG10634 | ||
| Length: | 250 (246) | ||
| Sequences: | 2042 | ||
| Seq/Len: | 8.30 |
| NAGD
Paralog alert: 0.22 [within 20: 0.01] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 210_G | 217_T | 5.916 | 1.00 | |
| 4_K | 195_E | 4.827 | 1.00 | |
| 32_M | 67_V | 3.076 | 1.00 | |
| 197_V | 218_I | 2.949 | 1.00 | |
| 142_A | 160_C | 2.566 | 1.00 | |
| 208_L | 212_Q | 2.547 | 1.00 | |
| 164_E | 171_P | 2.537 | 1.00 | |
| 216_E | 238_S | 2.524 | 1.00 | |
| 50_Q | 65_D | 2.377 | 1.00 | |
| 5_N | 189_M | 2.259 | 1.00 | |
| 179_P | 183_R | 2.254 | 1.00 | |
| 164_E | 170_K | 2.239 | 1.00 | |
| 140_F | 171_P | 2.04 | 1.00 | |
| 3_I | 216_E | 1.997 | 1.00 | |
| 207_I | 217_T | 1.988 | 1.00 | |
| 14_L | 40_L | 1.942 | 1.00 | |
| 50_Q | 54_N | 1.937 | 1.00 | |
| 8_C | 199_V | 1.921 | 1.00 | |
| 6_V | 197_V | 1.904 | 1.00 | |
| 242_P | 246_E | 1.83 | 1.00 | |
| 7_I | 41_L | 1.807 | 1.00 | |
| 92_E | 120_R | 1.755 | 1.00 | |
| 86_K | 105_T | 1.715 | 1.00 | |
| 30_G | 34_K | 1.709 | 1.00 | |
| 51_D | 54_N | 1.671 | 1.00 | |
| 243_S | 246_E | 1.667 | 1.00 | |
| 147_T | 165_K | 1.665 | 1.00 | |
| 191_A | 196_T | 1.631 | 1.00 | |
| 211_F | 238_S | 1.626 | 1.00 | |
| 20_A | 25_A | 1.62 | 1.00 | |
| 21_V | 243_S | 1.603 | 1.00 | |
| 30_G | 33_D | 1.588 | 1.00 | |
| 198_I | 215_L | 1.587 | 1.00 | |
| 75_T | 141_I | 1.577 | 1.00 | |
| 10_I | 40_L | 1.567 | 1.00 | |
| 29_H | 33_D | 1.538 | 1.00 | |
| 5_N | 191_A | 1.527 | 1.00 | |
| 31_I | 36_L | 1.525 | 1.00 | |
| 49_G | 73_M | 1.519 | 1.00 | |
| 225_S | 229_D | 1.508 | 1.00 | |
| 182_I | 209_A | 1.487 | 1.00 | |
| 221_L | 242_P | 1.459 | 0.99 | |
| 39_V | 188_K | 1.452 | 0.99 | |
| 225_S | 230_I | 1.451 | 0.99 | |
| 226_S | 229_D | 1.429 | 0.99 | |
| 53_A | 57_A | 1.42 | 0.99 | |
| 80_R | 104_F | 1.397 | 0.99 | |
| 119_T | 126_M | 1.383 | 0.99 | |
| 128_H | 154_P | 1.383 | 0.99 | |
| 10_I | 13_V | 1.37 | 0.99 | |
| 54_N | 58_T | 1.363 | 0.99 | |
| 75_T | 115_I | 1.354 | 0.99 | |
| 218_I | 241_Y | 1.344 | 0.99 | |
| 134_V | 137_G | 1.337 | 0.99 | |
| 49_G | 98_E | 1.33 | 0.99 | |
| 138_A | 169_R | 1.321 | 0.99 | |
| 182_I | 198_I | 1.319 | 0.99 | |
| 161_A | 165_K | 1.319 | 0.99 | |
| 221_L | 225_S | 1.318 | 0.99 | |
| 4_K | 36_L | 1.316 | 0.99 | |
| 14_L | 28_L | 1.314 | 0.99 | |
| 8_C | 244_V | 1.305 | 0.98 | |
| 6_V | 31_I | 1.305 | 0.98 | |
| 54_N | 57_A | 1.303 | 0.98 | |
| 29_H | 62_D | 1.301 | 0.98 | |
| 14_L | 61_V | 1.295 | 0.98 | |
| 10_I | 15_M | 1.28 | 0.98 | |
| 186_L | 196_T | 1.278 | 0.98 | |
| 185_A | 189_M | 1.256 | 0.98 | |
| 134_V | 163_I | 1.249 | 0.98 | |
| 202_N | 224_V | 1.249 | 0.98 | |
| 75_T | 174_V | 1.242 | 0.98 | |
| 116_V | 160_C | 1.241 | 0.98 | |
| 97_H | 101_K | 1.232 | 0.98 | |
| 24_A | 244_V | 1.228 | 0.97 | |
| 141_I | 174_V | 1.225 | 0.97 | |
| 219_L | 225_S | 1.215 | 0.97 | |
| 6_V | 36_L | 1.211 | 0.97 | |
| 48_T | 51_D | 1.209 | 0.97 | |
| 89_V | 99_L | 1.205 | 0.97 | |
| 221_L | 240_I | 1.184 | 0.97 | |
| 97_H | 100_Y | 1.184 | 0.97 | |
| 182_I | 215_L | 1.182 | 0.97 | |
| 16_H | 19_V | 1.169 | 0.96 | |
| 74_A | 181_I | 1.167 | 0.96 | |
| 45_P | 71_S | 1.161 | 0.96 | |
| 76_A | 102_A | 1.158 | 0.96 | |
| 25_A | 29_H | 1.157 | 0.96 | |
| 26_E | 245_A | 1.151 | 0.96 | |
| 53_A | 65_D | 1.149 | 0.96 | |
| 227_L | 231_D | 1.149 | 0.96 | |
| 86_K | 112_D | 1.148 | 0.96 | |
| 161_A | 164_E | 1.145 | 0.96 | |
| 3_I | 197_V | 1.127 | 0.95 | |
| 192_H | 195_E | 1.123 | 0.95 | |
| 53_A | 68_F | 1.12 | 0.95 | |
| 57_A | 62_D | 1.113 | 0.95 | |
| 26_E | 29_H | 1.109 | 0.95 | |
| 24_A | 61_V | 1.108 | 0.95 | |
| 90_V | 130_A | 1.107 | 0.95 | |
| 21_V | 24_A | 1.102 | 0.94 | |
| 123_N | 126_M | 1.101 | 0.94 | |
| 23_G | 26_E | 1.093 | 0.94 | |
| 145_P | 173_Y | 1.09 | 0.94 | |
| 132_Y | 135_A | 1.081 | 0.94 | |
| 8_C | 27_F | 1.081 | 0.94 | |
| 202_N | 205_T | 1.076 | 0.93 | |
| 86_K | 107_T | 1.068 | 0.93 | |
| 82_Q | 139_R | 1.065 | 0.93 | |
| 72_A | 76_A | 1.064 | 0.93 | |
| 9_D | 12_G | 1.06 | 0.93 | |
| 139_R | 172_F | 1.058 | 0.93 | |
| 40_L | 63_V | 1.058 | 0.93 | |
| 50_Q | 97_H | 1.052 | 0.92 | |
| 178_S | 212_Q | 1.041 | 0.92 | |
| 76_A | 80_R | 1.038 | 0.92 | |
| 128_H | 153_Y | 1.035 | 0.92 | |
| 77_D | 184_A | 1.035 | 0.92 | |
| 132_Y | 150_R | 1.03 | 0.91 | |
| 7_I | 185_A | 1.028 | 0.91 | |
| 5_N | 37_P | 1.012 | 0.90 | |
| 208_L | 235_F | 1.001 | 0.90 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3kc2A | 2 | 0.988 | 100 | 0.376 | Contact Map | 0.73 |
| 2ho4A | 2 | 0.98 | 100 | 0.403 | Contact Map | 0.805 |
| 1zjjA | 2 | 0.984 | 100 | 0.445 | Contact Map | 0.828 |
| 4i9fA | 2 | 0.98 | 100 | 0.472 | Contact Map | 0.716 |
| 4jdpA | 2 | 1 | 100 | 0.476 | Contact Map | 0.816 |
| 2oycA | 1 | 1 | 100 | 0.481 | Contact Map | 0.699 |
| 3eprA | 1 | 1 | 100 | 0.492 | Contact Map | 0.787 |
| 2c4nA | 1 | 1 | 100 | 0.495 | Contact Map | 0.777 |
| 1vjrA | 1 | 1 | 100 | 0.5 | Contact Map | 0.773 |
| 3pdwA | 1 | 1 | 100 | 0.508 | Contact Map | 0.76 |
Sequence Conservation (Image Generated using WebLogo v3)