| UniProt: | P0AEW4 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG12187 | ||
| Length: | 275 (256) | ||
| Sequences: | 1892 | ||
| Seq/Len: | 7.39 |
| CPDA
Paralog alert: 0.26 [within 20: 0.01] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 148_E | 192_K | 3.97 | 1.00 | |
| 17_I | 58_L | 3.63 | 1.00 | |
| 16_R | 247_E | 3.556 | 1.00 | |
| 162_L | 200_L | 2.97 | 1.00 | |
| 140_S | 182_N | 2.711 | 1.00 | |
| 129_S | 163_L | 2.7 | 1.00 | |
| 19_Q | 62_T | 2.689 | 1.00 | |
| 60_V | 162_L | 2.597 | 1.00 | |
| 18_L | 49_I | 2.54 | 1.00 | |
| 48_A | 243_W | 2.403 | 1.00 | |
| 62_T | 162_L | 2.401 | 1.00 | |
| 117_F | 123_Q | 2.363 | 1.00 | |
| 115_R | 150_K | 2.344 | 1.00 | |
| 123_Q | 150_K | 2.317 | 1.00 | |
| 66_A | 73_A | 2.261 | 1.00 | |
| 190_L | 215_R | 2.229 | 1.00 | |
| 148_E | 193_F | 2.163 | 1.00 | |
| 50_R | 85_R | 2.116 | 1.00 | |
| 125_L | 147_L | 2.094 | 1.00 | |
| 91_L | 126_L | 2.076 | 1.00 | |
| 117_F | 157_R | 1.991 | 1.00 | |
| 129_S | 165_H | 1.989 | 1.00 | |
| 46_L | 50_R | 1.985 | 1.00 | |
| 200_L | 246_L | 1.975 | 1.00 | |
| 138_E | 181_R | 1.96 | 1.00 | |
| 46_L | 84_F | 1.951 | 1.00 | |
| 58_L | 89_V | 1.938 | 1.00 | |
| 182_N | 185_E | 1.937 | 1.00 | |
| 17_I | 246_L | 1.932 | 1.00 | |
| 163_L | 199_L | 1.884 | 1.00 | |
| 65_L | 77_F | 1.868 | 1.00 | |
| 141_E | 145_E | 1.843 | 1.00 | |
| 146_W | 150_K | 1.83 | 1.00 | |
| 125_L | 150_K | 1.804 | 1.00 | |
| 116_V | 124_I | 1.797 | 1.00 | |
| 18_L | 245_T | 1.795 | 1.00 | |
| 211_D | 214_G | 1.776 | 1.00 | |
| 160_L | 198_Y | 1.76 | 1.00 | |
| 43_Q | 83_S | 1.742 | 1.00 | |
| 124_I | 160_L | 1.72 | 1.00 | |
| 77_F | 81_I | 1.684 | 1.00 | |
| 122_W | 248_L | 1.684 | 1.00 | |
| 141_E | 185_E | 1.684 | 1.00 | |
| 144_L | 185_E | 1.682 | 1.00 | |
| 150_K | 153_D | 1.682 | 1.00 | |
| 61_A | 90_W | 1.65 | 1.00 | |
| 144_L | 189_V | 1.64 | 1.00 | |
| 61_A | 77_F | 1.638 | 1.00 | |
| 115_R | 123_Q | 1.636 | 1.00 | |
| 148_E | 189_V | 1.628 | 1.00 | |
| 114_K | 126_L | 1.618 | 1.00 | |
| 78_A | 82_A | 1.609 | 1.00 | |
| 117_F | 150_K | 1.545 | 1.00 | |
| 43_Q | 80_G | 1.542 | 1.00 | |
| 140_S | 143_Q | 1.534 | 1.00 | |
| 113_A | 143_Q | 1.489 | 0.99 | |
| 147_L | 151_L | 1.479 | 0.99 | |
| 52_H | 56_F | 1.465 | 0.99 | |
| 15_V | 124_I | 1.457 | 0.99 | |
| 209_D | 216_R | 1.43 | 0.99 | |
| 186_L | 190_L | 1.427 | 0.99 | |
| 21_T | 62_T | 1.425 | 0.99 | |
| 220_T | 244_R | 1.375 | 0.99 | |
| 70_S | 73_A | 1.362 | 0.99 | |
| 123_Q | 157_R | 1.353 | 0.99 | |
| 201_C | 219_A | 1.337 | 0.98 | |
| 160_L | 200_L | 1.3 | 0.98 | |
| 148_E | 152_A | 1.291 | 0.98 | |
| 20_I | 61_A | 1.287 | 0.98 | |
| 21_T | 220_T | 1.244 | 0.97 | |
| 126_L | 162_L | 1.244 | 0.97 | |
| 23_T | 61_A | 1.238 | 0.97 | |
| 249_H | 255_T | 1.22 | 0.97 | |
| 127_L | 147_L | 1.215 | 0.97 | |
| 161_L | 190_L | 1.207 | 0.96 | |
| 137_G | 165_H | 1.19 | 0.96 | |
| 123_Q | 159_T | 1.183 | 0.96 | |
| 151_L | 161_L | 1.177 | 0.96 | |
| 114_K | 146_W | 1.176 | 0.96 | |
| 89_V | 114_K | 1.154 | 0.95 | |
| 186_L | 199_L | 1.152 | 0.95 | |
| 167_P | 201_C | 1.147 | 0.95 | |
| 21_T | 24_H | 1.141 | 0.95 | |
| 145_E | 149_R | 1.14 | 0.95 | |
| 51_P | 149_R | 1.137 | 0.94 | |
| 62_T | 91_L | 1.135 | 0.94 | |
| 19_Q | 200_L | 1.135 | 0.94 | |
| 115_R | 125_L | 1.129 | 0.94 | |
| 152_A | 193_F | 1.125 | 0.94 | |
| 204_I | 219_A | 1.125 | 0.94 | |
| 23_T | 81_I | 1.109 | 0.93 | |
| 20_I | 45_V | 1.098 | 0.93 | |
| 18_L | 56_F | 1.075 | 0.92 | |
| 20_I | 49_I | 1.072 | 0.92 | |
| 14_R | 249_H | 1.071 | 0.92 | |
| 121_Q | 157_R | 1.07 | 0.92 | |
| 66_A | 69_Q | 1.066 | 0.92 | |
| 80_G | 83_S | 1.065 | 0.91 | |
| 56_F | 86_A | 1.058 | 0.91 | |
| 147_L | 189_V | 1.057 | 0.91 | |
| 207_E | 221_P | 1.052 | 0.91 | |
| 160_L | 248_L | 1.044 | 0.90 | |
| 21_T | 61_A | 1.041 | 0.90 | |
| 71_S | 75_Q | 1.035 | 0.90 | |
| 39_W | 76_H | 1.033 | 0.90 | |
| 75_Q | 79_E | 1.031 | 0.90 | |
| 121_Q | 158_H | 1.021 | 0.89 | |
| 167_P | 186_L | 1.015 | 0.89 | |
| 125_L | 151_L | 1.01 | 0.88 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 3d03A | 6 | 0.9236 | 100 | 0.383 | Contact Map | 0.852 |
| 3ib7A | 1 | 0.9855 | 100 | 0.402 | Contact Map | 0.725 |
| 2nxfA | 1 | 0.8873 | 100 | 0.436 | Contact Map | 0.798 |
| 3tghA | 1 | 0.8982 | 100 | 0.494 | Contact Map | 0.67 |
| 1uteA | 1 | 0.9309 | 100 | 0.499 | Contact Map | 0.672 |
| 2xmoA | 2 | 0.9382 | 100 | 0.528 | Contact Map | 0.716 |
| 1xzwA | 2 | 0.9127 | 100 | 0.539 | Contact Map | 0.724 |
| 2qfpA | 4 | 0.9127 | 100 | 0.549 | Contact Map | 0.76 |
| 2yeqA | 2 | 0.9345 | 100 | 0.55 | Contact Map | 0.682 |
| 2yvtA | 1 | 0.7891 | 100 | 0.561 | Contact Map | 0.534 |
Sequence Conservation (Image Generated using WebLogo v3)