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OPENSEQ.org

GLCG - Protein GlcG
UniProt: P0AEQ1 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12952
Length: 134 (133)
Sequences: 1019
Seq/Len: 7.66

GLCG
Paralog alert: 0.30 [within 20: 0.01] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
22_E 25_K 3.592 1.00
16_I 43_A 3.383 1.00
33_A 58_S 3.157 1.00
13_S 45_S 2.553 1.00
33_A 41_L 2.409 1.00
30_V 124_V 2.193 1.00
22_E 123_Q 2.166 1.00
31_S 44_L 2.138 1.00
15_I 111_V 1.962 1.00
13_S 20_Q 1.932 1.00
7_L 42_L 1.867 1.00
73_K 122_A 1.855 1.00
33_A 44_L 1.757 1.00
22_E 26_N 1.675 1.00
126_K 130_A 1.631 1.00
116_L 120_Q 1.608 1.00
41_L 44_L 1.591 1.00
71_E 100_P 1.568 1.00
15_I 128_A 1.565 1.00
35_A 110_A 1.543 1.00
41_L 59_Q 1.513 1.00
113_V 125_A 1.51 0.99
95_L 118_G 1.503 0.99
19_G 111_V 1.473 0.99
31_S 54_A 1.438 0.99
33_A 59_Q 1.413 0.99
57_I 114_S 1.394 0.99
101_V 129_A 1.392 0.99
60_E 91_L 1.391 0.99
99_V 122_A 1.389 0.99
26_N 123_Q 1.385 0.99
19_G 128_A 1.382 0.99
15_I 132_L 1.355 0.99
53_I 68_G 1.311 0.98
24_Q 47_M 1.304 0.98
20_Q 32_I 1.299 0.98
63_R 67_L 1.297 0.98
49_D 106_Q 1.291 0.98
15_I 101_V 1.286 0.98
31_S 50_C 1.276 0.98
17_A 21_E 1.27 0.98
19_G 32_I 1.264 0.98
72_T 98_G 1.257 0.98
102_V 107_I 1.256 0.97
20_Q 45_S 1.255 0.97
96_E 122_A 1.253 0.97
53_I 67_L 1.24 0.97
44_L 55_A 1.22 0.97
56_Y 59_Q 1.219 0.97
18_A 131_V 1.185 0.96
9_Q 12_A 1.173 0.96
68_G 75_Y 1.166 0.96
9_Q 45_S 1.121 0.94
28_W 116_L 1.079 0.93
36_D 46_R 1.076 0.92
23_A 30_V 1.075 0.92
12_A 43_A 1.074 0.92
16_I 45_S 1.071 0.92
50_C 54_A 1.07 0.92
30_V 115_G 1.06 0.92
23_A 124_V 1.051 0.91
38_G 46_R 1.048 0.91
122_A 126_K 1.045 0.91
17_A 45_S 1.039 0.91
21_E 25_K 1.031 0.90
20_Q 24_Q 1.029 0.90
12_A 34_V 1.017 0.89
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2a2lA411000.126Contact Map0.868
3fpwA10.99251000.132Contact Map0.706
3mq0A20.977677.40.886Contact Map0.246
2o0yA40.977676.40.887Contact Map0.29
1yspA10.90372.50.891Contact Map0.286
3obfA20.903690.893Contact Map0.273
2g7uA40.955266.80.895Contact Map0.249
2o99A40.917963.30.897Contact Map0.343
2ia2A40.955263.20.897Contact Map0.309
1iruM20.358257.90.901Contact Map0.166

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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