| UniProt: | P0AEH3 | Sequence |
Download Alignment We filter this alignment to remove sites that have > 75% gaps before running GREMLIN. |
| EcoGene: | EG13184 | ||
| Length: | 153 (149) | ||
| Sequences: | 1535 | ||
| Seq/Len: | 10.30 |
| ELAA
Paralog alert: 0.52 [within 20: 0.01] - ratio of genomes with paralogs |
Legend: The darker and larger the blue dots, the higher coevolution strength.
Residue pairs sorted by coevolution strength:
| i | j | Scaled Score | Prob | |
| 100_L | 129_F | 3.706 | 1.00 | |
| 63_A | 99_T | 2.809 | 1.00 | |
| 121_Q | 131_P | 2.464 | 1.00 | |
| 115_G | 136_Y | 2.421 | 1.00 | |
| 25_C | 38_D | 2.337 | 1.00 | |
| 96_M | 127_F | 2.3 | 1.00 | |
| 23_L | 83_S | 2.256 | 1.00 | |
| 100_L | 112_V | 2.243 | 1.00 | |
| 77_I | 96_M | 2.218 | 1.00 | |
| 53_G | 91_V | 2.196 | 1.00 | |
| 66_L | 78_G | 2.143 | 1.00 | |
| 23_L | 81_I | 2.092 | 1.00 | |
| 61_A | 82_V | 2.089 | 1.00 | |
| 118_A | 135_V | 2.049 | 1.00 | |
| 13_S | 16_Q | 1.919 | 1.00 | |
| 121_Q | 144_I | 1.906 | 1.00 | |
| 100_L | 148_R | 1.887 | 1.00 | |
| 137_E | 140_G | 1.87 | 1.00 | |
| 19_A | 54_W | 1.757 | 1.00 | |
| 135_V | 142_P | 1.757 | 1.00 | |
| 98_K | 101_E | 1.731 | 1.00 | |
| 93_Q | 127_F | 1.648 | 1.00 | |
| 34_C | 139_D | 1.561 | 1.00 | |
| 53_G | 61_A | 1.56 | 1.00 | |
| 7_L | 16_Q | 1.541 | 1.00 | |
| 62_Y | 81_I | 1.533 | 1.00 | |
| 80_V | 96_M | 1.531 | 1.00 | |
| 136_Y | 145_G | 1.517 | 1.00 | |
| 51_I | 99_T | 1.516 | 1.00 | |
| 60_V | 86_L | 1.514 | 1.00 | |
| 121_Q | 125_Q | 1.482 | 1.00 | |
| 17_L | 21_L | 1.48 | 1.00 | |
| 32_Q | 117_Q | 1.467 | 1.00 | |
| 52_L | 59_L | 1.451 | 1.00 | |
| 111_P | 147_A | 1.44 | 1.00 | |
| 54_W | 59_L | 1.411 | 1.00 | |
| 26_A | 30_V | 1.41 | 1.00 | |
| 26_A | 83_S | 1.403 | 0.99 | |
| 77_I | 80_V | 1.395 | 0.99 | |
| 93_Q | 126_S | 1.378 | 0.99 | |
| 122_N | 125_Q | 1.349 | 0.99 | |
| 117_Q | 143_H | 1.344 | 0.99 | |
| 115_G | 138_E | 1.335 | 0.99 | |
| 93_Q | 97_S | 1.328 | 0.99 | |
| 35_P | 38_D | 1.323 | 0.99 | |
| 20_L | 62_Y | 1.313 | 0.99 | |
| 63_A | 80_V | 1.297 | 0.99 | |
| 125_Q | 131_P | 1.294 | 0.99 | |
| 92_G | 123_F | 1.255 | 0.99 | |
| 26_A | 37_Q | 1.255 | 0.99 | |
| 133_T | 145_G | 1.254 | 0.99 | |
| 132_V | 147_A | 1.246 | 0.98 | |
| 102_T | 105_H | 1.245 | 0.98 | |
| 68_S | 76_V | 1.23 | 0.98 | |
| 34_C | 141_I | 1.228 | 0.98 | |
| 21_L | 39_I | 1.189 | 0.98 | |
| 66_L | 76_V | 1.167 | 0.97 | |
| 131_P | 144_I | 1.149 | 0.97 | |
| 20_L | 52_L | 1.145 | 0.97 | |
| 28_F | 117_Q | 1.127 | 0.97 | |
| 58_E | 85_A | 1.125 | 0.97 | |
| 76_V | 115_G | 1.12 | 0.96 | |
| 132_V | 145_G | 1.106 | 0.96 | |
| 115_G | 145_G | 1.099 | 0.96 | |
| 32_Q | 143_H | 1.094 | 0.96 | |
| 76_V | 113_Y | 1.093 | 0.96 | |
| 25_C | 29_V | 1.084 | 0.96 | |
| 25_C | 36_Y | 1.06 | 0.95 | |
| 51_I | 102_T | 1.051 | 0.94 | |
| 22_Q | 26_A | 1.042 | 0.94 | |
| 65_I | 103_C | 1.04 | 0.94 | |
| 113_Y | 145_G | 1.032 | 0.94 | |
| 55_K | 60_V | 1.015 | 0.93 | |
| 31_E | 87_R | 1.009 | 0.93 | |
| 69_D | 74_P | 1.004 | 0.93 | |
| 34_C | 138_E | 1.001 | 0.92 |
- Text file of predictions (all 3L/2 predictions)
- Generate restraints for ROSETTA Structure Modeling
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
| PDB | Chains | Cov | P(%) | HHΔ | Acc | |
| 1xebA | 8 | 0.9739 | 100 | 0.4 | Contact Map | 0.863 |
| 1kzfA | 1 | 0.9869 | 99.9 | 0.41 | Contact Map | 0.597 |
| 3p2hA | 1 | 0.9739 | 99.9 | 0.423 | Contact Map | 0.679 |
| 1ro5A | 1 | 0.9804 | 99.9 | 0.425 | Contact Map | 0.562 |
| 2g0bA | 8 | 0.9804 | 99.9 | 0.45 | Contact Map | 0.629 |
| 1q2yA | 1 | 0.902 | 99.9 | 0.476 | Contact Map | 0.819 |
| 2jdcA | 1 | 0.915 | 99.9 | 0.482 | Contact Map | 0.686 |
| 3efaA | 1 | 0.9281 | 99.9 | 0.486 | Contact Map | 0.669 |
| 1y9wA | 2 | 0.8954 | 99.7 | 0.593 | Contact Map | 0.632 |
| 1yvkA | 4 | 0.9085 | 99.7 | 0.613 | Contact Map | 0.551 |
Sequence Conservation (Image Generated using WebLogo v3)