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OPENSEQ.org

YAJC - UPF0092 membrane protein YajC
UniProt: P0ADZ7 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11096
Length: 110 (108)
Sequences: 1086
Seq/Len: 10.06

YAJC
Paralog alert: 0.01 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
85_L 91_V 3.084 1.00
24_I 28_V 2.995 1.00
51_K 55_S 2.652 1.00
68_L 91_V 2.58 1.00
48_E 51_K 2.549 1.00
34_F 38_I 2.447 1.00
49_H 53_M 2.397 1.00
44_K 48_E 2.181 1.00
68_L 85_L 1.906 1.00
31_G 39_L 1.799 1.00
51_K 54_D 1.771 1.00
69_V 94_K 1.762 1.00
50_K 54_D 1.719 1.00
56_I 72_V 1.715 1.00
45_R 48_E 1.642 1.00
62_V 83_I 1.637 1.00
43_Q 47_K 1.613 1.00
33_I 37_M 1.567 1.00
86_N 89_T 1.562 1.00
65_N 97_F 1.557 1.00
5_I 8_A 1.527 1.00
75_V 95_R 1.52 1.00
27_L 31_G 1.49 1.00
39_L 43_Q 1.488 1.00
29_V 32_L 1.485 1.00
27_L 30_F 1.458 1.00
56_I 98_V 1.454 1.00
21_M 26_M 1.44 1.00
82_A 90_E 1.436 1.00
40_R 44_K 1.417 1.00
30_F 34_F 1.359 0.99
52_L 101_V 1.355 0.99
26_M 29_V 1.346 0.99
4_F 8_A 1.303 0.99
38_I 43_Q 1.3 0.99
46_T 50_K 1.264 0.99
94_K 97_F 1.243 0.98
85_L 89_T 1.223 0.98
69_V 80_Y 1.218 0.98
23_L 27_L 1.192 0.98
4_F 7_D 1.176 0.98
85_L 93_I 1.174 0.98
6_S 9_V 1.172 0.98
84_A 88_T 1.166 0.97
52_L 55_S 1.09 0.96
82_A 92_V 1.089 0.96
73_T 90_E 1.081 0.95
81_I 98_V 1.063 0.95
23_L 29_V 1.059 0.95
43_Q 46_T 1.05 0.94
5_I 9_V 1.03 0.94
4_F 9_V 1.017 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
2rddB10.336499.30.626Contact Map0.201
4hczA20.481862.30.892Contact Map0.672
4l5gA20.536452.20.898Contact Map0.357
4hw9A70.847.50.901Contact Map0.738
3udcA70.827346.70.902Contact Map0.477
2vv5A70.842.20.904Contact Map0.682
1vq8T10.663638.80.906Contact Map0.427
2k4kA10.472737.50.907Contact Map0.227
2jwaA20.363629.60.912Contact Map0.323
3lrxA60.490929.50.912Contact Map0.06

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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