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OPENSEQ.org

RL23 - 50S ribosomal protein L23
UniProt: P0ADZ0 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10883
Length: 100 (95)
Sequences: 1580
Seq/Len: 16.63

RL23
Paralog alert: 0.02 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
43_I 60_T 3.776 1.00
60_T 81_K 2.656 1.00
13_A 33_K 2.654 1.00
36_K 62_V 2.652 1.00
65_G 79_D 2.457 1.00
56_E 88_K 2.357 1.00
61_L 84_Y 2.285 1.00
29_T 84_Y 2.221 1.00
63_V 82_K 2.201 1.00
54_E 88_K 2.137 1.00
11_L 50_L 2.078 1.00
63_V 80_W 2.03 1.00
48_Q 54_E 2.008 1.00
26_K 29_T 2.001 1.00
67_V 76_R 1.917 1.00
12_R 35_A 1.906 1.00
42_E 45_A 1.768 1.00
67_V 74_I 1.714 1.00
54_E 91_Q 1.644 1.00
39_T 42_E 1.603 1.00
15_H 33_K 1.602 1.00
30_I 93_L 1.595 1.00
33_K 80_W 1.579 1.00
45_A 49_K 1.575 1.00
59_N 86_T 1.569 1.00
70_H 73_R 1.55 1.00
76_R 79_D 1.534 1.00
34_V 43_I 1.433 1.00
41_A 45_A 1.414 1.00
56_E 86_T 1.361 0.99
36_K 79_D 1.333 0.99
41_A 44_K 1.298 0.99
20_A 31_V 1.287 0.99
7_L 49_K 1.268 0.99
47_V 55_V 1.251 0.99
5_E 42_E 1.193 0.98
56_E 59_N 1.128 0.97
31_V 84_Y 1.113 0.96
47_V 85_V 1.112 0.96
29_T 59_N 1.108 0.96
15_H 31_V 1.055 0.95
47_V 50_L 1.035 0.94
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
4kixT111000.032Contact Map0.636
2zjrQ10.951000.085Contact Map0.617
3j3wT10.941000.088Contact Map0.707
4btdX10.951000.089Contact Map0.721
3tveT10.921000.09Contact Map0.801
3j39X10.871000.206Contact Map0.754
3zf7X10.8799.90.229Contact Map0.754
2go5410.8799.90.229Contact Map0.731
3j3bX10.8799.90.234Contact Map0.702
3u5eX10.8799.90.237Contact Map0.838

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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