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OPENSEQ.org

RL14 - 50S ribosomal protein L14
UniProt: P0ADY3 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG10875
Length: 123 (122)
Sequences: 1052
Seq/Len: 8.62

RL14
Paralog alert: 0.04 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
19_V 84_C 3.965 1.00
41_I 58_L 3.827 1.00
21_C 39_I 3.651 1.00
7_M 18_R 3.524 1.00
5_Q 20_M 3.152 1.00
19_V 41_I 3.091 1.00
2_I 21_C 2.332 1.00
34_G 68_G 2.163 1.00
33_A 62_V 2.094 1.00
20_M 44_K 2.057 1.00
9_N 81_G 1.874 1.00
3_Q 6_T 1.787 1.00
10_V 19_V 1.787 1.00
40_K 59_K 1.723 1.00
18_R 45_E 1.716 1.00
7_M 20_M 1.696 1.00
59_K 89_N 1.691 1.00
51_K 95_I 1.68 1.00
88_N 92_E 1.625 1.00
70_R 76_V 1.613 1.00
60_A 84_C 1.576 1.00
20_M 42_T 1.55 1.00
42_T 55_G 1.491 1.00
19_V 43_I 1.487 1.00
91_S 111_K 1.467 1.00
9_N 18_R 1.466 1.00
34_G 69_V 1.457 0.99
95_I 109_S 1.448 0.99
52_V 56_D 1.442 0.99
103_V 107_L 1.427 0.99
38_I 112_F 1.426 0.99
2_I 6_T 1.388 0.99
35_V 69_V 1.362 0.99
71_R 106_E 1.304 0.99
38_I 87_L 1.26 0.98
77_I 123_L 1.246 0.98
25_L 40_K 1.239 0.98
4_E 20_M 1.237 0.98
2_I 8_L 1.227 0.98
63_V 103_V 1.178 0.97
4_E 23_K 1.165 0.96
86_L 95_I 1.118 0.95
113_M 116_I 1.108 0.95
91_S 112_F 1.105 0.95
68_G 76_V 1.092 0.94
61_V 115_I 1.058 0.93
107_L 116_I 1.054 0.93
58_L 86_L 1.053 0.93
8_L 39_I 1.021 0.91
47_I 51_K 1.02 0.91
7_M 44_K 1.01 0.91
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
1whiA10.9919100-0.008Contact Map0.89
3v2dO10.9919100-0.007Contact Map0.87
4kixK10.9919100-0.002Contact Map0.84
3bboM10.98371000.005Contact Map0.662
3j21J10.95931000.053Contact Map0.675
3zf7W10.95931000.054Contact Map0.581
1vq8K10.95931000.057Contact Map0.733
3u5eV10.95931000.066Contact Map0.798
1pxfA10.74818.90.937Contact Map0.008
3g48A20.66678.40.946Contact Map0.003

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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