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YFHB - Uncharacterized protein YfhB
UniProt: P0AD42 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG11371
Length: 211 (201)
Sequences: 2133
Seq/Len: 10.61

YFHB
Paralog alert: 0.61 [within 20: 0.00] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
147_Q 153_W 4.109 1.00
169_E 194_F 2.761 1.00
123_Q 145_Q 2.649 1.00
114_D 140_N 2.548 1.00
162_H 166_A 2.342 1.00
101_Q 132_D 2.286 1.00
51_A 55_K 2.263 1.00
108_L 115_I 2.211 1.00
64_S 160_L 2.077 1.00
119_T 126_V 2.065 1.00
32_R 36_L 2.041 1.00
108_L 139_V 2.035 1.00
106_T 110_S 2.023 1.00
123_Q 127_E 2.014 1.00
80_Q 84_A 1.986 1.00
147_Q 155_L 1.971 1.00
107_Y 112_D 1.94 1.00
189_N 207_L 1.877 1.00
105_T 109_L 1.856 1.00
117_L 136_L 1.799 1.00
7_R 112_D 1.791 1.00
116_W 171_K 1.783 1.00
54_I 58_A 1.72 1.00
76_E 80_Q 1.703 1.00
31_L 36_L 1.702 1.00
11_F 182_Y 1.635 1.00
101_Q 105_T 1.628 1.00
126_V 141_L 1.61 1.00
127_E 131_F 1.608 1.00
192_L 198_R 1.606 1.00
83_Q 128_A 1.605 1.00
55_K 60_R 1.579 1.00
18_H 22_M 1.575 1.00
75_S 78_R 1.557 1.00
176_L 179_Y 1.55 1.00
142_I 170_R 1.548 1.00
116_W 140_N 1.541 1.00
161_G 190_P 1.539 1.00
181_G 191_L 1.52 1.00
62_P 65_L 1.51 1.00
117_L 130_Y 1.505 1.00
163_E 167_Q 1.489 1.00
145_Q 155_L 1.483 1.00
105_T 108_L 1.48 1.00
10_F 116_W 1.478 1.00
172_I 176_L 1.463 1.00
74_H 78_R 1.453 1.00
61_W 65_L 1.438 1.00
13_L 117_L 1.428 1.00
130_Y 141_L 1.427 1.00
207_L 210_L 1.424 1.00
29_Y 85_D 1.413 1.00
181_G 195_C 1.405 0.99
168_L 191_L 1.402 0.99
81_T 85_D 1.401 0.99
76_E 148_R 1.386 0.99
189_N 210_L 1.382 0.99
163_E 166_A 1.381 0.99
118_I 168_L 1.349 0.99
179_Y 195_C 1.34 0.99
142_I 167_Q 1.335 0.99
107_Y 182_Y 1.322 0.99
104_L 136_L 1.314 0.99
144_S 159_C 1.293 0.99
33_R 36_L 1.292 0.99
104_L 115_I 1.264 0.99
97_F 201_V 1.263 0.99
142_I 159_C 1.25 0.99
79_L 124_P 1.249 0.99
144_S 154_V 1.249 0.99
147_Q 151_G 1.24 0.98
200_R 203_P 1.232 0.98
108_L 134_P 1.221 0.98
181_G 192_L 1.218 0.98
77_A 81_T 1.21 0.98
13_L 129_V 1.192 0.98
165_V 169_E 1.189 0.98
13_L 126_V 1.182 0.98
19_Q 97_F 1.162 0.97
11_F 17_L 1.149 0.97
195_C 198_R 1.144 0.97
9_V 107_Y 1.142 0.97
91_R 132_D 1.142 0.97
56_G 59_A 1.138 0.97
59_A 62_P 1.127 0.97
193_Y 210_L 1.103 0.96
166_A 170_R 1.1 0.96
10_F 195_C 1.086 0.96
32_R 35_P 1.071 0.95
68_W 153_W 1.055 0.95
53_L 57_R 1.054 0.95
26_F 74_H 1.039 0.94
115_I 136_L 1.033 0.94
115_I 118_I 1.032 0.94
114_D 139_V 1.026 0.94
9_V 180_S 1.019 0.93
78_R 81_T 1.016 0.93
107_Y 180_S 1.016 0.93
17_L 100_V 1.015 0.93
33_R 85_D 1.004 0.93
165_V 194_F 1.002 0.92
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3fvvA20.94311000.443Contact Map0.748
4as2A40.98199.90.474Contact Map0.694
4gxtA10.98199.90.49Contact Map0.729
1l7mA20.876899.90.529Contact Map0.855
3m1yA40.87299.90.538Contact Map0.806
1y8aA10.9199.90.564Contact Map0.676
3p96A10.881599.90.569Contact Map0.742
1rkuA20.810499.80.583Contact Map0.67
1nnlA20.900599.80.613Contact Map0.702
4ap9A40.848399.80.613Contact Map0.629

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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