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OPENSEQ.org

YFAE - Uncharacterized ferredoxin-like protein YfaE
UniProt: P0ABW3 Sequence
Download Alignment
We filter this alignment to remove sites that have > 75% gaps before running GREMLIN.
EcoGene: EG12360
Length: 84 (82)
Sequences: 3253
Seq/Len: 39.67

YFAE
Paralog alert: 0.79 [within 20: 0.06] - ratio of genomes with paralogs
GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Scaled Score Prob
20_P 28_S 3.683 1.00
53_Q 77_K 3.126 1.00
47_T 71_P 2.742 1.00
23_L 35_Y 2.706 1.00
51_A 81_E 2.541 1.00
27_E 38_R 2.44 1.00
3_R 14_L 2.431 1.00
17_D 20_P 2.179 1.00
49_L 69_I 2.128 1.00
61_L 65_Q 1.891 1.00
55_D 77_K 1.757 1.00
48_R 68_E 1.732 1.00
27_E 35_Y 1.671 1.00
3_R 12_Q 1.596 1.00
26_L 33_V 1.576 1.00
5_T 12_Q 1.511 1.00
50_V 83_E 1.44 1.00
53_Q 78_G 1.391 0.99
24_A 38_R 1.368 0.99
22_L 69_I 1.363 0.99
46_R 68_E 1.318 0.99
46_R 70_L 1.304 0.99
57_I 75_R 1.297 0.99
5_T 81_E 1.28 0.99
49_L 54_V 1.262 0.99
5_T 10_G 1.231 0.98
20_P 25_A 1.181 0.98
7_R 81_E 1.178 0.98
22_L 71_P 1.137 0.97
55_D 75_R 1.136 0.97
50_V 81_E 1.135 0.97
35_Y 38_R 1.13 0.97
4_V 22_L 1.119 0.96
13_L 25_A 1.102 0.96
33_V 71_P 1.096 0.96
56_W 74_C 1.093 0.96
8_I 83_E 1.09 0.96
46_R 63_F 1.067 0.95
25_A 29_H 1.06 0.95
54_V 74_C 1.035 0.94
48_R 83_E 1.033 0.94
36_Q 44_S 1.026 0.94
36_Q 39_E 1.021 0.93
54_V 80_I 1.011 0.93
3_R 79_D 1.004 0.93
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Scaled Score = (raw_score/average(raw_scores)) > 1 are listed. For all 3L/2 predictions, click on one of the links below.
HHsearch Results: GREMLIN results overlayed on top 10 PDB hits:
Legend: Blue filled circles are GREMLIN results (Scaled_score >1). The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on 10 HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov P(%) HHΔ   Acc
3zyyX20.988199.80.176Contact Map0.636
2piaA10.976299.80.204Contact Map0.898
1iueA20.988199.80.239Contact Map0.872
1jq4A10.988199.80.239Contact Map0.466
1frrA20.988199.80.24Contact Map0.907
3wcqA10.988199.80.241Contact Map0.866
1qoaA20.988199.80.244Contact Map0.889
1wriA10.976299.80.246Contact Map0.767
1frdA10.988199.80.246Contact Map0.857
1a70A10.988199.70.248Contact Map0.841

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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